148 related articles for article (PubMed ID: 9014752)
1. Time course of methotrexate polyglutamate formation and degradation in the pre-B-leukaemia cell line Nalm6 and in lymphoblasts from children with leukaemia.
Buchholz B; Frei E; Eisenbarth J; Weigand M; Ludwig R
Eur J Cancer; 1996 Nov; 32A(12):2101-7. PubMed ID: 9014752
[TBL] [Abstract][Full Text] [Related]
2. Comparative analysis of methotrexate polyglutamates in lymphoblast preparations from bone marrow and blood, and the contribution of residual red blood cells.
Weigand M; Frei E; Graf N; Wiessler M
J Cancer Res Clin Oncol; 2000 Jul; 126(7):407-11. PubMed ID: 10929763
[TBL] [Abstract][Full Text] [Related]
3. Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity.
Galpin AJ; Schuetz JD; Masson E; Yanishevski Y; Synold TW; Barredo JC; Pui CH; Relling MV; Evans WE
Mol Pharmacol; 1997 Jul; 52(1):155-63. PubMed ID: 9224825
[TBL] [Abstract][Full Text] [Related]
4. Evidence for negative feedback of extracellular methotrexate on blasts of acute lymphoblastic leukemia in vitro.
Hum MC; Smith AK; Lark RH; Winick NJ; Kamen BA
Pharmacotherapy; 1997; 17(6):1260-6. PubMed ID: 9399609
[TBL] [Abstract][Full Text] [Related]
5. Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.
Masson E; Relling MV; Synold TW; Liu Q; Schuetz JD; Sandlund JT; Pui CH; Evans WE
J Clin Invest; 1996 Jan; 97(1):73-80. PubMed ID: 8550853
[TBL] [Abstract][Full Text] [Related]
6. Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy.
Nersting J; Nielsen SN; Grell K; Paerregaard M; Abrahamsson J; Lund B; Jonsson OG; Pruunsild K; Vaitkeviciene G; Kanerva J; Schmiegelow K;
Cancer Chemother Pharmacol; 2019 Jan; 83(1):53-60. PubMed ID: 30324220
[TBL] [Abstract][Full Text] [Related]
7. Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group study.
Whitehead VM; Vuchich MJ; Lauer SJ; Mahoney D; Carroll AJ; Shuster JJ; Esseltine DW; Payment C; Look AT; Akabutu J
Blood; 1992 Sep; 80(5):1316-23. PubMed ID: 1381244
[TBL] [Abstract][Full Text] [Related]
8. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
Panetta JC; Yanishevski Y; Pui CH; Sandlund JT; Rubnitz J; Rivera GK; Ribeiro R; Evans WE; Relling MV
Cancer Chemother Pharmacol; 2002 Nov; 50(5):419-28. PubMed ID: 12439601
[TBL] [Abstract][Full Text] [Related]
9. Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia.
Lin JT; Tong WP; Trippett TM; Niedzwiecki D; Tao Y; Tan C; Steinherz P; Schweitzer BI; Bertino JR
Leuk Res; 1991; 15(12):1191-6. PubMed ID: 1722550
[TBL] [Abstract][Full Text] [Related]
10. Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease.
Göker E; Lin JT; Trippett T; Elisseyeff Y; Tong WP; Niedzwiecki D; Tan C; Steinherz P; Schweitzer BI; Bertino JR
Leukemia; 1993 Jul; 7(7):1000-4. PubMed ID: 7686600
[TBL] [Abstract][Full Text] [Related]
11. Ex vivo resistance in childhood acute lymphoblastic leukemia: Correlations between BCRP, MRP1, MRP4 and MRP5 ABC transporter expression and intracellular methotrexate polyglutamate accumulation.
Jaramillo AC; Cloos J; Lemos C; Stam RW; Kaspers GJL; Jansen G; Peters GJ
Leuk Res; 2019 Apr; 79():45-51. PubMed ID: 30849662
[TBL] [Abstract][Full Text] [Related]
12. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.
Synold TW; Relling MV; Boyett JM; Rivera GK; Sandlund JT; Mahmoud H; Crist WM; Pui CH; Evans WE
J Clin Invest; 1994 Nov; 94(5):1996-2001. PubMed ID: 7525652
[TBL] [Abstract][Full Text] [Related]
13. gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
Longo GS; Gorlick R; Tong WP; Lin S; Steinherz P; Bertino JR
Oncol Res; 1997; 9(5):259-63. PubMed ID: 9306433
[TBL] [Abstract][Full Text] [Related]
14. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: a pilot prognostic factor analysis.
Whitehead VM; Rosenblatt DS; Vuchich MJ; Shuster JJ; Witte A; Beaulieu D
Blood; 1990 Jul; 76(1):44-9. PubMed ID: 1694703
[TBL] [Abstract][Full Text] [Related]
15. [Primary study on establishment of namalwa 12/MTX resistant cell strain and its mechanism].
Chen J; Gu LJ; Ying DM; Shen M; Wu HJ
Ai Zheng; 2002 Dec; 21(12):1335-40. PubMed ID: 12520743
[TBL] [Abstract][Full Text] [Related]
16. Methotrexate polyglutamation may lack prognostic significance in children with B-cell precursor acute lymphoblastic leukemia treated with intensive oral methotrexate.
Mantadakis E; Smith AK; Hynan L; Winick NJ; Kamen BA
J Pediatr Hematol Oncol; 2002 Nov; 24(8):636-42. PubMed ID: 12439035
[TBL] [Abstract][Full Text] [Related]
17. Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group Study.
Whitehead VM; Vuchich MJ; Cooley LD; Lauer SJ; Mahoney DH; Shuster JJ; Payment C; Koch PA; Akabutu JJ; Bowen T; Kamen BA; Ravindranath Y; Emami A; Look AT; Beardsley GP; Pullen DJ; Camitta B
Leuk Lymphoma; 1998 Nov; 31(5-6):507-19. PubMed ID: 9922041
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, retention, and biological activity of methotrexate polyglutamates in cultured human breast cancer cells.
Jolivet J; Schilsky RL; Bailey BD; Drake JC; Chabner BA
J Clin Invest; 1982 Aug; 70(2):351-60. PubMed ID: 6178756
[TBL] [Abstract][Full Text] [Related]
19. Methotrexate polyglutamate synthesis in lymphoblasts from children with acute lymphoblastic leukemia.
Whitehead VM; Rosenblatt DS; Vuchich MJ; Beaulieu D
Dev Pharmacol Ther; 1987; 10(6):443-8. PubMed ID: 2445535
[TBL] [Abstract][Full Text] [Related]
20. Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
Rots MG; Pieters R; Kaspers GJ; van Zantwijk CH; Noordhuis P; Mauritz R; Veerman AJ; Jansen G; Peters GJ
Blood; 1999 Feb; 93(3):1067-74. PubMed ID: 9920857
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
