These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 9016326)

  • 1. Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]- 1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity.
    Dutta AK; Coffey LL; Reith ME
    J Med Chem; 1997 Jan; 40(1):35-43. PubMed ID: 9016326
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.
    Dutta AK; Xu C; Reith ME
    J Med Chem; 1998 Aug; 41(17):3293-7. PubMed ID: 9703474
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potent and selective ligands for the dopamine transporter (DAT): structure-activity relationship studies of novel 4-[2-(diphenylmethoxy)ethyl]-1-(3-phenylpropyl)piperidine analogues.
    Dutta AK; Coffey LL; Reith ME
    J Med Chem; 1998 Feb; 41(5):699-705. PubMed ID: 9513598
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
    Kolhatkar RB; Ghorai SK; George C; Reith ME; Dutta AK
    J Med Chem; 2003 May; 46(11):2205-15. PubMed ID: 12747792
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-activity relationship studies of novel 4-[2-[bis(4-fluorophenyl)methoxy]ethyl]-1-(3-phenylpropyl)piperidine analogs: synthesis and biological evaluation at the dopamine and serotonin transporter sites.
    Dutta AK; Xu C; Reith ME
    J Med Chem; 1996 Feb; 39(3):749-56. PubMed ID: 8576918
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Heteroaromatic analogs of 1-[2-(diphenylmethoxy)ethyl]- and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as high-affinity dopamine reuptake inhibitors.
    Matecka D; Lewis D; Rothman RB; Dersch CM; Wojnicki FH; Glowa JR; DeVries AC; Pert A; Rice KC
    J Med Chem; 1997 Feb; 40(5):705-16. PubMed ID: 9057857
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.
    Kline RH; Izenwasser S; Katz JL; Joseph DB; Bowen WD; Newman AH
    J Med Chem; 1997 Mar; 40(6):851-7. PubMed ID: 9083473
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.
    Zhou J; Zhang A; Kläss T; Johnson KM; Wang CZ; Ye YP; Kozikowski AP
    J Med Chem; 2003 May; 46(10):1997-2007. PubMed ID: 12723962
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.
    Kulkarni SS; Grundt P; Kopajtic T; Katz JL; Newman AH
    J Med Chem; 2004 Jun; 47(13):3388-98. PubMed ID: 15189035
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and preliminary characterization of a high-affinity novel radioligand for the dopamine transporter.
    Dutta AK; Reith ME; Madras BK
    Synapse; 2001 Feb; 39(2):175-81. PubMed ID: 11180505
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton.
    Kozikowski AP; Araldi GL; Boja J; Meil WM; Johnson KM; Flippen-Anderson JL; George C; Saiah E
    J Med Chem; 1998 May; 41(11):1962-9. PubMed ID: 9599245
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine.
    Greiner E; Prisinzano T; Johnson EM; Dersch CM; Marcus J; Partilla JS; Rothman RB; Jacobson AE; Rice KC
    J Med Chem; 2003 Apr; 46(8):1465-9. PubMed ID: 12672246
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues: selective ligands for the dopamine transporter.
    Agoston GE; Wu JH; Izenwasser S; George C; Katz J; Kline RH; Newman AH
    J Med Chem; 1997 Dec; 40(26):4329-39. PubMed ID: 9435902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.
    Dutta AK; Fei XS; Beardsley PM; Newman JL; Reith ME
    J Med Chem; 2001 Mar; 44(6):937-48. PubMed ID: 11300876
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 2-Carbomethoxy-3-(diarylmethoxy)-1 alpha H, 5 alpha H-tropane analogs: synthesis and inhibition of binding at the dopamine transporter and comparison with piperazines of the GBR series.
    Meltzer PC; Liang AY; Madras BK
    J Med Chem; 1996 Jan; 39(2):371-9. PubMed ID: 8558504
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.
    Ghorai SK; Cook C; Davis M; Venkataraman SK; George C; Beardsley PM; Reith ME; Dutta AK
    J Med Chem; 2003 Mar; 46(7):1220-8. PubMed ID: 12646032
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, structure, dopamine transporter affinity, and dopamine uptake inhibition of 6-alkyl-3-benzyl-2-[(methoxycarbonyl)methyl]tropane derivatives.
    Lomenzo SA; Izenwasser S; Katz JL; Terry PD; Zhu N; Klein CL; Trudell ML
    J Med Chem; 1997 Dec; 40(26):4406-14. PubMed ID: 9435910
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.
    Cao J; Kulkarni SS; Husbands SM; Bowen WD; Williams W; Kopajtic T; Katz JL; George C; Newman AH
    J Med Chem; 2003 Jun; 46(13):2589-98. PubMed ID: 12801223
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.
    Houlihan WJ; Boja JW; Parrino VA; Kopajtic TA; Kuhar MJ
    J Med Chem; 1996 Dec; 39(25):4935-41. PubMed ID: 8960553
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and transporter binding properties of bridged piperazine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909).
    Zhang Y; Rothman RB; Dersch CM; de Costa BR; Jacobson AE; Rice KC
    J Med Chem; 2000 Dec; 43(25):4840-9. PubMed ID: 11123994
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.