These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 9020517)

  • 1. Prediction of teratogenic potency of valproate analogues using cerebellar aggregation cultures.
    Maar TE; Ellerbeck U; Bock E; Nau H; Schousboe A; Berezin V
    Toxicology; 1997 Jan; 116(1-3):159-68. PubMed ID: 9020517
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction of embryotoxic effects of valproic acid-derivatives with molecular in vitro methods.
    Lampen A; Göttlicher M; Nau H
    ALTEX; 2001; 18(2):123-6. PubMed ID: 11378687
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Valproic acid-induced neural tube defects in mouse and human: aspects of chirality, alternative drug development, pharmacokinetics and possible mechanisms.
    Nau H; Hauck RS; Ehlers K
    Pharmacol Toxicol; 1991 Nov; 69(5):310-21. PubMed ID: 1803343
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Validation of an in vitro teratology system using chiral substances: stereoselective teratogenicity of 4-yn-valproic acid in cultured mouse embryos.
    Andrews JE; Ebron-McCoy M; Bojic U; Nau H; Kavlock RJ
    Toxicol Appl Pharmacol; 1995 Jun; 132(2):310-6. PubMed ID: 7785058
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multiple effects of pentyl-4-yn-VPA enantiomers: from toxicity to short-term memory enhancement.
    Gotfryd K; Owczarek S; Hoffmann K; Klementiev B; Nau H; Berezin V; Bock E; Walmod PS
    Neuropharmacology; 2007 Mar; 52(3):764-78. PubMed ID: 17095022
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hydroxamic acid and fluorinated derivatives of valproic acid: anticonvulsant activity, neurotoxicity and teratogenicity.
    Gravemann U; Volland J; Nau H
    Neurotoxicol Teratol; 2008; 30(5):390-4. PubMed ID: 18455366
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cell proliferation, migration and CAM-dependent neurite outgrowth as developmental in vitro endpoints for screening teratogenic potential: Application to valproic acid and related analogues of varying potency.
    Bacon CL; Berezin V; Bode G; Bock E; Bojic U; Doherty P; Ehlers K; Ellerbeck U; Julien P; Kawa A; Maar TE; Nau H; Pirovano R; Regan CM; Schousboe A; Spezia F; Walsh FS; Williams EJ
    Toxicol In Vitro; 1998 Apr; 12(2):101-9. PubMed ID: 20654391
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Teratogenic potency of valproate analogues evaluated by quantitative estimation of cellular morphology in vitro.
    Berezin V; Kawa A; Bojic U; Foley A; Nau H; Regan C; Edvardsen K; Bock E
    Toxicol In Vitro; 1996 Oct; 10(5):585-94. PubMed ID: 20650240
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Asymmetric synthesis and enantioselective teratogenicity of 2-n-propyl-4-pentenoic acid (4-en-VPA), an active metabolite of the anticonvulsant drug, valproic acid.
    Hauck RS; Nau H
    Toxicol Lett; 1989 Oct; 49(1):41-8. PubMed ID: 2510370
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereoselective dysmorphogenicity of the enantiomers of the valproic acid analogue 2-N-propyl-4-pentynoic acid (4-yn-VPA): cross-species evaluation in whole embryo culture.
    Andrews JE; Ebron-McCoy MT; Bojic U; Nau H; Kavlock RJ
    Teratology; 1997 May; 55(5):314-8. PubMed ID: 9261925
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The enantiomers of the valproic acid analogue 2-n-propyl-4-pentynoic acid (4-yn-VPA): asymmetric synthesis and highly stereoselective teratogenicity in mice.
    Hauck RS; Nau H
    Pharm Res; 1992 Jul; 9(7):850-5. PubMed ID: 1437995
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New molecular bioassays for the estimation of the teratogenic potency of valproic acid derivatives in vitro: activation of the peroxisomal proliferator-activated receptor (PPARdelta).
    Lampen A; Siehler S; Ellerbeck U; Göttlicher M; Nau H
    Toxicol Appl Pharmacol; 1999 Nov; 160(3):238-49. PubMed ID: 10544058
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacologic evaluation of various metabolites and analogs of valproic acid: teratogenic potencies in mice.
    Nau H; Löscher W
    Fundam Appl Toxicol; 1986 May; 6(4):669-76. PubMed ID: 3086174
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice.
    Okada A; Noyori H; Yagen B; Shimshoni JA; Bialer M; Fujiwara M
    Birth Defects Res B Dev Reprod Toxicol; 2009 Oct; 86(5):394-401. PubMed ID: 19830722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Short-time gene expression response to valproic acid and valproic acid analogs in mouse embryonic stem cells.
    Jergil M; Forsberg M; Salter H; Stockling K; Gustafson AL; Dencker L; Stigson M
    Toxicol Sci; 2011 Jun; 121(2):328-42. PubMed ID: 21427059
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Valproic acid-induced deregulation in vitro of genes associated in vivo with neural tube defects.
    Jergil M; Kultima K; Gustafson AL; Dencker L; Stigson M
    Toxicol Sci; 2009 Mar; 108(1):132-48. PubMed ID: 19136453
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Valnoctamide, valpromide and valnoctic acid are much less teratogenic in mice than valproic acid.
    Radatz M; Ehlers K; Yagen B; Bialer M; Nau H
    Epilepsy Res; 1998 Mar; 30(1):41-8. PubMed ID: 9551843
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Further branching of valproate-related carboxylic acids reduces the teratogenic activity, but not the anticonvulsant effect.
    Bojic U; Elmazar MM; Hauck RS; Nau H
    Chem Res Toxicol; 1996; 9(5):866-70. PubMed ID: 8828922
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The teratogenic potencies of valproic acid derivatives and their effects on biological end-points are related to changes in histone deacetylase and Erk1/2 activities.
    Gotfryd K; Hansen M; Kawa A; Ellerbeck U; Nau H; Berezin V; Bock E; Walmod PS
    Basic Clin Pharmacol Toxicol; 2011 Sep; 109(3):164-74. PubMed ID: 21439023
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core structure.
    Eickholt BJ; Towers GJ; Ryves WJ; Eikel D; Adley K; Ylinen LM; Chadborn NH; Harwood AJ; Nau H; Williams RS
    Mol Pharmacol; 2005 May; 67(5):1426-33. PubMed ID: 15687223
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.