103 related articles for article (PubMed ID: 9029055)
1. Metabolic inactivation of cytochrome P4502B1 by phencyclidine: immunochemical and radiochemical analyses of the protective effects of glutathione.
Sharma U; Roberts ES; Kent UM; Owens SM; Hollenberg PF
Drug Metab Dispos; 1997 Feb; 25(2):243-50. PubMed ID: 9029055
[TBL] [Abstract][Full Text] [Related]
2. Mechanism-based inactivation of rat liver cytochrome P4502B1 by phencyclidine and its oxidative product, the iminium ion.
Crowley JR; Hollenberg PF
Drug Metab Dispos; 1995 Aug; 23(8):786-93. PubMed ID: 7493543
[TBL] [Abstract][Full Text] [Related]
3. Inactivation of cytochrome P4502B1 by the monoamine oxidase inhibitors R-(-)-deprenyl and clorgyline.
Sharma U; Roberts ES; Hollenberg PF
Drug Metab Dispos; 1996 Jun; 24(6):669-75. PubMed ID: 8781784
[TBL] [Abstract][Full Text] [Related]
4. Bioactivation of phencyclidine in rat and human liver microsomes and recombinant P450 2B enzymes: evidence for the formation of a novel quinone methide intermediate.
Driscoll JP; Kornecki K; Wolkowski JP; Chupak L; Kalgutkar AS; O'Donnell JP
Chem Res Toxicol; 2007 Oct; 20(10):1488-97. PubMed ID: 17892269
[TBL] [Abstract][Full Text] [Related]
5. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2-phenyl-2-(1-piperidinyl)propane.
Chun J; Kent UM; Moss RM; Sayre LM; Hollenberg PF
Drug Metab Dispos; 2000 Aug; 28(8):905-11. PubMed ID: 10901699
[TBL] [Abstract][Full Text] [Related]
6. Mutation of a single residue (K262R) in P450 2B6 leads to loss of mechanism-based inactivation by phencyclidine.
Shebley M; Hollenberg PF
Drug Metab Dispos; 2007 Aug; 35(8):1365-71. PubMed ID: 17460030
[TBL] [Abstract][Full Text] [Related]
7. Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1-aminobenzotriazole.
Kent UM; Bend JR; Chamberlin BA; Gage DA; Hollenberg PF
Chem Res Toxicol; 1997 May; 10(5):600-8. PubMed ID: 9168259
[TBL] [Abstract][Full Text] [Related]
8. Selective pathways for the metabolism of phencyclidine by cytochrome p450 2b enzymes: identification of electrophilic metabolites, glutathione, and N-acetyl cysteine adducts.
Shebley M; Jushchyshyn MI; Hollenberg PF
Drug Metab Dispos; 2006 Mar; 34(3):375-83. PubMed ID: 16326815
[TBL] [Abstract][Full Text] [Related]
9. The mechanism-based inactivation of human cytochrome P450 2B6 by phencyclidine.
Jushchyshyn MI; Kent UM; Hollenberg PF
Drug Metab Dispos; 2003 Jan; 31(1):46-52. PubMed ID: 12485952
[TBL] [Abstract][Full Text] [Related]
10. Peroxynitrite-mediated nitration of tyrosine and inactivation of the catalytic activity of cytochrome P450 2B1.
Roberts ES; Lin Hl; Crowley JR; Vuletich JL; Osawa Y; Hollenberg PF
Chem Res Toxicol; 1998 Sep; 11(9):1067-74. PubMed ID: 9760281
[TBL] [Abstract][Full Text] [Related]
11. Mechanistic studies of cytochrome P450 2B1 inactivation by xanthates.
Yanev SG; Kent UM; Roberts ES; Ballou DP; Hollenberg PF
Arch Biochem Biophys; 2000 Jun; 378(1):157-66. PubMed ID: 10871056
[TBL] [Abstract][Full Text] [Related]
12. Phencyclidine iminium ion. NADPH-dependent metabolism, covalent binding to macromolecules, and inactivation of cytochrome(s) P-450.
Hoag MK; Trevor AJ; Kalir A; Castagnoli N
Drug Metab Dispos; 1987; 15(4):485-90. PubMed ID: 2888621
[TBL] [Abstract][Full Text] [Related]
13. Formation of a metabolic intermediate complex of cytochrome P4502B1 by clorgyline.
Sharma U; Roberts ES; Hollenberg PF
Drug Metab Dispos; 1996 Nov; 24(11):1247-53. PubMed ID: 8937860
[TBL] [Abstract][Full Text] [Related]
14. Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1.
Goosen TC; Mills DE; Hollenberg PF
J Pharmacol Exp Ther; 2001 Jan; 296(1):198-206. PubMed ID: 11123381
[TBL] [Abstract][Full Text] [Related]
15. Mechanism-based inactivation of cytochrome P450 2B1 by 8-methoxypsoralen and several other furanocoumarins.
Koenigs LL; Trager WF
Biochemistry; 1998 Sep; 37(38):13184-93. PubMed ID: 9748325
[TBL] [Abstract][Full Text] [Related]
16. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.
Zhao SX; Dalvie DK; Kelly JM; Soglia JR; Frederick KS; Smith EB; Obach RS; Kalgutkar AS
Chem Res Toxicol; 2007 Nov; 20(11):1649-57. PubMed ID: 17907785
[TBL] [Abstract][Full Text] [Related]
17. Influence of glutathione on the catalytic activity of reconstituted cytochrome P450 3A4.
Kim BR; Kim DH
Biochem Biophys Res Commun; 1998 Jan; 242(1):209-12. PubMed ID: 9439637
[TBL] [Abstract][Full Text] [Related]
18. Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes.
Ferrara R; Tolando R; King LJ; Manno M
Toxicol Appl Pharmacol; 1997 Apr; 143(2):420-8. PubMed ID: 9144458
[TBL] [Abstract][Full Text] [Related]
19. Mechanism-based inactivation of cytochrome P450 3A4 by 4-ipomeanol.
Alvarez-Diez TM; Zheng J
Chem Res Toxicol; 2004 Feb; 17(2):150-7. PubMed ID: 14967002
[TBL] [Abstract][Full Text] [Related]
20. Mechanism-based inactivation of rat liver cytochrome P-450 2B1 by 2-methoxy-5-nitrobenzyl bromide.
Armstrong AP; Hollenberg PF
Drug Metab Dispos; 1999 Jun; 27(6):741-5. PubMed ID: 10348806
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
