BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 9036839)

  • 41. Sulfonyl-containing nucleoside phosphotriesters and phosphoramidates as novel anticancer prodrugs of 5-fluoro-2'-deoxyuridine 5'-monophosphate (FdUMP).
    Sun YW; Chen KM; Kwon CH
    Mol Pharm; 2006; 3(2):161-73. PubMed ID: 16579645
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Synthesis and evaluation of 6-(dibromomethyl)-5-nitropyrimidines as potential antitumor agents.
    Thompson MD; Cupps TL; Wise DS; Wotring LL; Townsend LB
    J Med Chem; 1997 Feb; 40(5):766-70. PubMed ID: 9057863
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Inactivation of S-adenosyl-L-homocysteine hydrolase by 6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine and 6'-chloro-6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine. Antiviral and cytotoxic effects.
    Guillerm G; Muzard M; Glapski C; Pilard S; De Clercq E
    J Med Chem; 2006 Feb; 49(4):1223-6. PubMed ID: 16480257
    [TBL] [Abstract][Full Text] [Related]  

  • 44. In vitro optimization of non-small cell lung cancer activity with troxacitabine, L-1,3-dioxolane-cytidine, prodrugs.
    Radi M; Adema AD; Daft JR; Cho JH; Hoebe EK; Alexander LE; Peters GJ; Chu CK
    J Med Chem; 2007 May; 50(9):2249-53. PubMed ID: 17419604
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Cyclopropanecarboxylic acid esters as potential prodrugs with enhanced hydrolytic stability.
    Bender DM; Peterson JA; McCarthy JR; Gunaydin H; Takano Y; Houk KN
    Org Lett; 2008 Feb; 10(3):509-11. PubMed ID: 18181639
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Synthesis and antiviral activity of certain 5'-modified analogs of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole.
    Gudmundsson KS; Drach JC; Wotring LL; Townsend LB
    J Med Chem; 1997 Feb; 40(5):785-93. PubMed ID: 9057865
    [TBL] [Abstract][Full Text] [Related]  

  • 47. An original pronucleotide strategy for the simultaneous delivery of two bioactive drugs.
    Villard AL; Aubertin AM; Peyrottes S; Périgaud C
    Eur J Med Chem; 2021 Apr; 216():113315. PubMed ID: 33711763
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Glycosidic prodrugs of highly potent bifunctional duocarmycin derivatives for selective treatment of cancer.
    Tietze LF; von Hof JM; Müller M; Krewer B; Schuberth I
    Angew Chem Int Ed Engl; 2010 Sep; 49(40):7336-9. PubMed ID: 20799305
    [No Abstract]   [Full Text] [Related]  

  • 49. Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: synthesis and evaluation of 6-substituted purine l-ribonucleosides.
    Hocek M; Silhár P; Shih IH; Mabery E; Mackman R
    Bioorg Med Chem Lett; 2006 Oct; 16(20):5290-3. PubMed ID: 16905315
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Synthesis and antitumor activity of CBI-bearing ester and carbamate prodrugs of CC-1065 analogue.
    Wang Y; Li L; Tian Z; Jiang W; Larrick JW
    Bioorg Med Chem; 2006 Dec; 14(23):7854-61. PubMed ID: 16908174
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Structure-activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs.
    Liu WQ; Vidal M; Olszowy C; Million E; Lenoir C; Dhôtel H; Garbay C
    J Med Chem; 2004 Feb; 47(5):1223-33. PubMed ID: 14971902
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Identification of KD5170: a novel mercaptoketone-based histone deacetylase inhibitor.
    Payne JE; Bonnefous C; Hassig CA; Symons KT; Guo X; Nguyen PM; Annable T; Wash PL; Hoffman TZ; Rao TS; Shiau AK; Malecha JW; Noble SA; Hager JH; Smith ND
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6093-6. PubMed ID: 18954983
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide.
    Karakuş S; Güniz Küçükgüzel S; Küçükgüzel I; De Clercq E; Pannecouque C; Andrei G; Snoeck R; Sahin F; Bayrak OF
    Eur J Med Chem; 2009 Sep; 44(9):3591-5. PubMed ID: 19324473
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Nucleoside/nucleobase transporters: drug targets of the future?
    Köse M; Schiedel AC
    Future Med Chem; 2009 May; 1(2):303-26. PubMed ID: 21425971
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Emerging targeting concepts membrane-associated protein thiol-disulfide interchange activity: a potential target for anti-viral and anti-tumor drug design.
    Shen WC
    J Drug Target; 1999; 6(6):387-9. PubMed ID: 10937284
    [No Abstract]   [Full Text] [Related]  

  • 56. A new homodimer of aciclovir as a prodrug with increased solubility and antiviral activity.
    Brandi G; Rossi L; Schiavano GF; Millo E; Magnani M
    Int J Antimicrob Agents; 2009 Aug; 34(2):177-80. PubMed ID: 19394201
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Modified nucleoside 5'-triphosphonates as a new type of antiviral agents.
    Shirokova EA; Shipitsin AV; Victorova LS; Dyatkina NB; Goryunova LE; Beabealashvilli RS; Hamilton CJ; Roberts SM; Krayevsky AA
    Nucleosides Nucleotides; 1999; 18(4-5):1027-8. PubMed ID: 10432736
    [No Abstract]   [Full Text] [Related]  

  • 58. Novel fluorinated prodrugs for activation by carboxypeptidase G2 showing good in vivo antitumor activity in gene-directed enzyme prodrug therapy.
    Davies LC; Friedlos F; Hedley D; Martin J; Ogilvie LM; Scanlon IJ; Springer CJ
    J Med Chem; 2005 Aug; 48(16):5321-8. PubMed ID: 16078849
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Studies on the mechanisms of activation of indolequinone phosphoramidate prodrugs.
    Hernick M; Borch RF
    J Med Chem; 2003 Jan; 46(1):148-54. PubMed ID: 12502368
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Medicinal chemistry of antiviral/anticancer prodrugs subjected to phosphate conjugation.
    Kalász H; Adem A; Hasan MY; Adeghate E; Ram N; Gulyás Z; Tekes K
    Mini Rev Med Chem; 2010 Aug; 10(9):822-45. PubMed ID: 20491651
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.