BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 9038241)

  • 1. Activation of CGS 12094 (prinomide metabolite) to 1,4-benzoquinone by myeloperoxidase: implications for human idiosyncratic agranulocytosis.
    Parrish DD; Schlosser MJ; Kapeghian JC; Traina VM
    Fundam Appl Toxicol; 1997 Feb; 35(2):197-204. PubMed ID: 9038241
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prinomide tromethamine pharmacokinetics: mutually dependent saturable and competitive protein binding between prinomide and its own metabolite.
    Kochak GM; Pai S; Iannucci R; Honc F; Kachmar D; Perrino P; Egger H
    Pharm Res; 1993 Jan; 10(1):49-55. PubMed ID: 8430060
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxidation of propylthiouracil to reactive metabolites by activated neutrophils. Implications for agranulocytosis.
    Waldhauser L; Uetrecht J
    Drug Metab Dispos; 1991; 19(2):354-9. PubMed ID: 1676636
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neutrophil Myeloperoxidase-Mediated N-Demethylation of Quetiapine Leads to
    Rashid MH; Babu D; Tran N; Reiz B; Siraki AG
    Chem Res Toxicol; 2022 Jun; 35(6):1001-1010. PubMed ID: 35575633
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oxidation of a metabolite of indomethacin (Desmethyldeschlorobenzoylindomethacin) to reactive intermediates by activated neutrophils, hypochlorous acid, and the myeloperoxidase system.
    Ju C; Uetrecht JP
    Drug Metab Dispos; 1998 Jul; 26(7):676-80. PubMed ID: 9660850
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N-chlorination of phenytoin by myeloperoxidase to a reactive metabolite.
    Uetrecht J; Zahid N
    Chem Res Toxicol; 1988; 1(3):148-51. PubMed ID: 2856515
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Involvement of myeloperoxidase and NADPH oxidase in the covalent binding of amodiaquine and clozapine to neutrophils: implications for drug-induced agranulocytosis.
    Lobach AR; Uetrecht J
    Chem Res Toxicol; 2014 Apr; 27(4):699-709. PubMed ID: 24588327
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Disposition and metabolism of prinomide in laboratory animals.
    Egger H; Itterly W; John V; Rodebaugh R; Shimanskas C; Stancato F; Kapoor A
    Drug Metab Dispos; 1988; 16(4):568-75. PubMed ID: 2903025
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neutrophil- and myeloperoxidase-mediated metabolism of reduced nimesulide: evidence for bioactivation.
    Yang M; Chordia MD; Li F; Huang T; Linden J; Macdonald TL
    Chem Res Toxicol; 2010 Nov; 23(11):1691-700. PubMed ID: 20939553
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Peroxidase-mediated bioactivation of hydroxylated metabolites of carbamazepine and phenytoin.
    Lu W; Uetrecht JP
    Drug Metab Dispos; 2008 Aug; 36(8):1624-36. PubMed ID: 18463199
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolism of ticlopidine by activated neutrophils: implications for ticlopidine-induced agranulocytosis.
    Liu ZC; Uetrecht JP
    Drug Metab Dispos; 2000 Jul; 28(7):726-30. PubMed ID: 10859143
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigating the mechanisms of aromatic amine-induced protein free radical formation by quantitative structure-activity relationships: implications for drug-induced agranulocytosis.
    Siraki AG; Jiang J; Mason RP
    Chem Res Toxicol; 2010 May; 23(5):880-7. PubMed ID: 20199096
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Myeloperoxidase-mediated activation of xenobiotics by human leukocytes.
    Hofstra AH; Uetrecht JP
    Toxicology; 1993 Oct; 82(1-3):221-42. PubMed ID: 8236277
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolism of vesnarinone by activated neutrophils: implications for vesnarinone-induced agranulocytosis.
    Uetrecht JP; Zahid N; Whitfield D
    J Pharmacol Exp Ther; 1994 Sep; 270(3):865-72. PubMed ID: 7932198
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Predicting drug-induced agranulocytosis: characterizing neutrophil-generated metabolites of a model compound, DMP 406, and assessing the relevance of an in vitro apoptosis assay for identifying drugs that may cause agranulocytosis.
    Iverson S; Zahid N; Uetrecht JP
    Chem Biol Interact; 2002 Nov; 142(1-2):175-99. PubMed ID: 12399162
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Carbamazepine metabolism to a reactive intermediate by the myeloperoxidase system of activated neutrophils.
    Furst SM; Uetrecht JP
    Biochem Pharmacol; 1993 Mar; 45(6):1267-75. PubMed ID: 8385460
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolic activation of hydroquinone by macrophage peroxidase.
    Schlosser MJ; Kalf GF
    Chem Biol Interact; 1989; 72(1-2):191-207. PubMed ID: 2555072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Possible role of free radical formation in clozapine (clozaril)-induced agranulocytosis.
    Fischer V; Haar JA; Greiner L; Lloyd RV; Mason RP
    Mol Pharmacol; 1991 Nov; 40(5):846-53. PubMed ID: 1658615
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-Chlorination and oxidation of procainamide by myeloperoxidase: toxicological implications.
    Uetrecht JP; Zahid N
    Chem Res Toxicol; 1991; 4(2):218-22. PubMed ID: 1664258
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neutrophil cytotoxicity of the chemically reactive metabolite(s) of clozapine: possible role in agranulocytosis.
    Williams DP; Pirmohamed M; Naisbitt DJ; Maggs JL; Park BK
    J Pharmacol Exp Ther; 1997 Dec; 283(3):1375-82. PubMed ID: 9400013
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.