BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 9045629)

  • 1. Interaction of alcohols and anesthetics with protein kinase Calpha.
    Slater SJ; Kelly MB; Larkin JD; Ho C; Mazurek A; Taddeo FJ; Yeager MD; Stubbs CD
    J Biol Chem; 1997 Mar; 272(10):6167-73. PubMed ID: 9045629
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The nature of the hydrophobic n-alkanol binding site within the C1 domains of protein kinase Calpha.
    Slater SJ; Malinowski SA; Stubbs CD
    Biochemistry; 2004 Jun; 43(23):7601-9. PubMed ID: 15182202
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of membrane lipid-independent protein kinase Calpha activity by phorbol esters, diacylglycerols, and bryostatin-1.
    Slater SJ; Taddeo FJ; Mazurek A; Stagliano BA; Milano SK; Kelly MB; Ho C; Stubbs CD
    J Biol Chem; 1998 Sep; 273(36):23160-8. PubMed ID: 9722545
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein kinase Calpha contains two activator binding sites that bind phorbol esters and diacylglycerols with opposite affinities.
    Slater SJ; Ho C; Kelly MB; Larkin JD; Taddeo FJ; Yeager MD; Stubbs CD
    J Biol Chem; 1996 Mar; 271(9):4627-31. PubMed ID: 8617724
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification, characterization, and comparison of n-alkanols and anesthetics binding to the C1b subdomain of protein kinase cα: similar function with different binding sites.
    Lian F; Wang Z; Zhou Z; Xu G
    J Recept Signal Transduct Res; 2020 Apr; 40(2):109-116. PubMed ID: 32054382
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synergistic activation of protein kinase Calpha, -betaI, and -gamma isoforms induced by diacylglycerol and phorbol ester: roles of membrane association and activating conformational changes.
    Slater SJ; Milano SK; Stagliano BA; Gergich KJ; Ho C; Mazurek A; Taddeo FJ; Kelly MB; Yeager MD; Stubbs CD
    Biochemistry; 1999 Mar; 38(12):3804-15. PubMed ID: 10090770
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Low- and high-affinity phorbol ester and diglyceride interactions with protein kinase C: 1-O-alkyl-2-acyl-sn-glycerol enhances phorbol ester- and diacylglycerol-induced activity but alone does not induce activity.
    Slater SJ; Seiz JL; Stagliano BA; Cook AC; Milano SK; Ho C; Stubbs CD
    Biochemistry; 2001 May; 40(20):6085-92. PubMed ID: 11352745
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of ethanol on protein kinase C alpha activity induced by association with Rho GTPases.
    Slater SJ; Cook AC; Seiz JL; Malinowski SA; Stagliano BA; Stubbs CD
    Biochemistry; 2003 Oct; 42(41):12105-14. PubMed ID: 14556642
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lipid-dependent activation of protein kinase C-alpha by normal alcohols.
    Shen YM; Chertihin OI; Biltonen RL; Sando JJ
    J Biol Chem; 1999 Nov; 274(48):34036-44. PubMed ID: 10567370
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains.
    Ananthanarayanan B; Stahelin RV; Digman MA; Cho W
    J Biol Chem; 2003 Nov; 278(47):46886-94. PubMed ID: 12954613
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phorbol esters and related analogs regulate the subcellular localization of beta 2-chimaerin, a non-protein kinase C phorbol ester receptor.
    Caloca MJ; Wang H; Delemos A; Wang S; Kazanietz MG
    J Biol Chem; 2001 May; 276(21):18303-12. PubMed ID: 11278894
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of ethanol on protein kinase C activity induced by filamentous actin.
    Slater SJ; Stagliano BA; Seiz JL; Curry JP; Milano SK; Gergich KJ; Stubbs CD
    Biochim Biophys Acta; 2001 Jan; 1544(1-2):207-16. PubMed ID: 11341930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ligand structure-activity requirements and phospholipid dependence for the binding of phorbol esters to protein kinase D.
    Wang QJ; Fang TW; Yang D; Lewin NE; Van Lint J; Marquez VE; Blumberg PM
    Mol Pharmacol; 2003 Dec; 64(6):1342-8. PubMed ID: 14645664
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein kinase C ligands based on tetrahydrofuran templates containing a new set of phorbol ester pharmacophores.
    Lee J; Kang JH; Lee SY; Han KC; Torres CM; Bhattacharyya DK; Blumberg PM; Marquez VE
    J Med Chem; 1999 Oct; 42(20):4129-39. PubMed ID: 10514283
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of protein kinase C catalytic activity by additional regions within the human protein kinase Calpha-regulatory domain lying outside of the pseudosubstrate sequence.
    Kirwan AF; Bibby AC; Mvilongo T; Riedel H; Burke T; Millis SZ; Parissenti AM
    Biochem J; 2003 Jul; 373(Pt 2):571-81. PubMed ID: 12710889
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kinetic analysis of the interaction of the C1 domain of protein kinase C with lipid membranes by stopped-flow spectroscopy.
    Dries DR; Newton AC
    J Biol Chem; 2008 Mar; 283(12):7885-93. PubMed ID: 18187412
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A phorbol ester binding domain of protein kinase C gamma. High affinity binding to a glutathione-S-transferase/Cys2 fusion protein.
    Quest AF; Bardes ES; Bell RM
    J Biol Chem; 1994 Jan; 269(4):2953-60. PubMed ID: 8300627
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interplay of C1 and C2 domains of protein kinase C-alpha in its membrane binding and activation.
    Medkova M; Cho W
    J Biol Chem; 1999 Jul; 274(28):19852-61. PubMed ID: 10391930
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Scanning mutagenesis studies reveal multiple distinct regions within the human protein kinase C alpha regulatory domain important for phorbol ester-dependent activation of the enzyme.
    Guo B; Reed K; Parissenti AM
    J Mol Biol; 2006 Mar; 357(3):820-32. PubMed ID: 16460753
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis of binding of high-affinity ligands to protein kinase C: prediction of the binding modes through a new molecular dynamics method and evaluation by site-directed mutagenesis.
    Pak Y; Enyedy IJ; Varady J; Kung JW; Lorenzo PS; Blumberg PM; Wang S
    J Med Chem; 2001 May; 44(11):1690-701. PubMed ID: 11356104
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.