BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 9054540)

  • 1. Biologically important conformations of aminoglycoside antibiotics bound to an aminoglycoside 3'-phosphotransferase as determined by transferred nuclear Overhauser effect spectroscopy.
    Cox JR; Serpersu EH
    Biochemistry; 1997 Mar; 36(9):2353-9. PubMed ID: 9054540
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regiospecificity of aminoglycoside phosphotransferase from Enterococci and Staphylococci (APH(3')-IIIa).
    Thompson PR; Hughes DW; Wright GD
    Biochemistry; 1996 Jul; 35(26):8686-95. PubMed ID: 8679631
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Solution studies of isepamicin and conformational comparisons between isepamicin and butirosin A when bound to an aminoglycoside 6'-N-acetyltransferase determined by NMR spectroscopy.
    DiGiammarino EL; Draker KA; Wright GD; Serpersu EH
    Biochemistry; 1998 Mar; 37(11):3638-44. PubMed ID: 9521682
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis of APH(3')-IIIa-mediated resistance to N1-substituted aminoglycoside antibiotics.
    Fong DH; Berghuis AM
    Antimicrob Agents Chemother; 2009 Jul; 53(7):3049-55. PubMed ID: 19433564
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aminoglycoside antibiotics bound to aminoglycoside-detoxifying enzymes and RNA adopt similar conformations.
    Cox JR; Ekman DR; DiGiammarino EL; Akal-Strader A; Serpersu EH
    Cell Biochem Biophys; 2000; 33(3):297-308. PubMed ID: 11325047
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The complete 1H NMR assignments of aminoglycoside antibiotics and conformational studies of butirosin A through the use of 2D NMR spectroscopy.
    Cox JR; Serpersu EH
    Carbohydr Res; 1995 Jul; 271(1):55-63. PubMed ID: 7544237
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thermodynamics of aminoglycoside binding to aminoglycoside-3'-phosphotransferase IIIa studied by isothermal titration calorimetry.
    Ozen C; Serpersu EH
    Biochemistry; 2004 Nov; 43(46):14667-75. PubMed ID: 15544337
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NMR detected hydrogen-deuterium exchange reveals differential dynamics of antibiotic- and nucleotide-bound aminoglycoside phosphotransferase 3'-IIIa.
    Norris AL; Serpersu EH
    J Am Chem Soc; 2009 Jun; 131(24):8587-94. PubMed ID: 19463004
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dissection of aminoglycoside-enzyme interactions: a calorimetric and NMR study of neomycin B binding to the aminoglycoside phosphotransferase(3')-IIIa.
    Ozen C; Malek JM; Serpersu EH
    J Am Chem Soc; 2006 Nov; 128(47):15248-54. PubMed ID: 17117877
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ATP binding enables broad antibiotic selectivity of aminoglycoside phosphotransferase(3')-IIIa: an elastic network analysis.
    Wieninger SA; Serpersu EH; Ullmann GM
    J Mol Biol; 2011 Jun; 409(3):450-65. PubMed ID: 21477597
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structures of antibiotic-bound complexes of aminoglycoside 2''-phosphotransferase IVa highlight the diversity in substrate binding modes among aminoglycoside kinases.
    Shi K; Houston DR; Berghuis AM
    Biochemistry; 2011 Jul; 50(28):6237-44. PubMed ID: 21678960
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Catalytic mechanism of enterococcal kanamycin kinase (APH(3')-IIIa): viscosity, thio, and solvent isotope effects support a Theorell-Chance mechanism.
    McKay GA; Wright GD
    Biochemistry; 1996 Jul; 35(26):8680-5. PubMed ID: 8679630
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prodigious substrate specificity of AAC(6')-APH(2"), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci.
    Daigle DM; Hughes DW; Wright GD
    Chem Biol; 1999 Feb; 6(2):99-110. PubMed ID: 10021417
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aminoglycoside antibiotic phosphotransferases are also serine protein kinases.
    Daigle DM; McKay GA; Thompson PR; Wright GD
    Chem Biol; 1999 Jan; 6(1):11-8. PubMed ID: 9889150
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The COOH terminus of aminoglycoside phosphotransferase (3')-IIIa is critical for antibiotic recognition and resistance.
    Thompson PR; Schwartzenhauer J; Hughes DW; Berghuis AM; Wright GD
    J Biol Chem; 1999 Oct; 274(43):30697-706. PubMed ID: 10521458
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Purification, characterization, and investigation of the mechanism of aminoglycoside 3'-phosphotransferase type Ia.
    Siregar JJ; Miroshnikov K; Mobashery S
    Biochemistry; 1995 Oct; 34(39):12681-8. PubMed ID: 7548020
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Detection of specific solvent rearrangement regions of an enzyme: NMR and ITC studies with aminoglycoside phosphotransferase(3')-IIIa.
    Ozen C; Norris AL; Land ML; Tjioe E; Serpersu EH
    Biochemistry; 2008 Jan; 47(1):40-9. PubMed ID: 18067326
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Broad spectrum aminoglycoside phosphotransferase type III from Enterococcus: overexpression, purification, and substrate specificity.
    McKay GA; Thompson PR; Wright GD
    Biochemistry; 1994 Jun; 33(22):6936-44. PubMed ID: 8204627
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Domain-domain interactions in the aminoglycoside antibiotic resistance enzyme AAC(6')-APH(2'').
    Boehr DD; Daigle DM; Wright GD
    Biochemistry; 2004 Aug; 43(30):9846-55. PubMed ID: 15274639
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Active-site labeling of an aminoglycoside antibiotic phosphotransferase (APH(3')-IIIa).
    McKay GA; Robinson RA; Lane WS; Wright GD
    Biochemistry; 1994 Nov; 33(47):14115-20. PubMed ID: 7947822
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.