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4. Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene. Bali D; Svetlanov A; Lee HW; Fusco-DeMane D; Leiser M; Li B; Barzilai N; Surana M; Hou H; Fleischer N J Biol Chem; 1995 Sep; 270(37):21464-7. PubMed ID: 7665557 [TBL] [Abstract][Full Text] [Related]
5. Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose. Terauchi Y; Sakura H; Yasuda K; Iwamoto K; Takahashi N; Ito K; Kasai H; Suzuki H; Ueda O; Kamada N J Biol Chem; 1995 Dec; 270(51):30253-6. PubMed ID: 8530440 [TBL] [Abstract][Full Text] [Related]
6. Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis. Grupe A; Hultgren B; Ryan A; Ma YH; Bauer M; Stewart TA Cell; 1995 Oct; 83(1):69-78. PubMed ID: 7553875 [TBL] [Abstract][Full Text] [Related]
7. Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities. Matschinsky FM; Glaser B; Magnuson MA Diabetes; 1998 Mar; 47(3):307-15. PubMed ID: 9519733 [TBL] [Abstract][Full Text] [Related]
8. [Diabetes caused by glucokinase mutation]. Eto K; Kadowaki T Nihon Rinsho; 1998 Jan; 56 Suppl 3():554-65. PubMed ID: 9513478 [No Abstract] [Full Text] [Related]
9. Effect of high-fat diet on glucose homeostasis and gene expression in glucokinase knockout mice. Gorman T; Hope DC; Brownlie R; Yu A; Gill D; Löfvenmark J; Wedin M; Mayers RM; Snaith MR; Smith DM Diabetes Obes Metab; 2008 Sep; 10(10):885-97. PubMed ID: 18034843 [TBL] [Abstract][Full Text] [Related]
10. Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease. Terauchi Y; Iwamoto K; Tamemoto H; Komeda K; Ishii C; Kanazawa Y; Asanuma N; Aizawa T; Akanuma Y; Yasuda K; Kodama T; Tobe K; Yazaki Y; Kadowaki T J Clin Invest; 1997 Mar; 99(5):861-6. PubMed ID: 9062343 [TBL] [Abstract][Full Text] [Related]
11. Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships. Gidh-Jain M; Takeda J; Xu LZ; Lange AJ; Vionnet N; Stoffel M; Froguel P; Velho G; Sun F; Cohen D Proc Natl Acad Sci U S A; 1993 Mar; 90(5):1932-6. PubMed ID: 8446612 [TBL] [Abstract][Full Text] [Related]
12. Glucokinase and glucose transporter expression in liver and islets: implications for control of glucose homoeostasis. Newgard CB; Quaade C; Hughes SD; Milburn JL Biochem Soc Trans; 1990 Oct; 18(5):851-3. PubMed ID: 2083694 [No Abstract] [Full Text] [Related]
13. Effects of glucose on insulin secretion, glucokinase activity, and transgene expression in transgenic mouse islets containing an upstream glucokinase promoter-human growth hormone fusion gene. Liang Y; Jetton TL; Zimmerman EC; Najafi H; Berner DK; Matschinsky FM; Magnuson MA Diabetes; 1994 Sep; 43(9):1138-45. PubMed ID: 8070614 [TBL] [Abstract][Full Text] [Related]
14. Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism. Niswender KD; Shiota M; Postic C; Cherrington AD; Magnuson MA J Biol Chem; 1997 Sep; 272(36):22570-5. PubMed ID: 9278411 [TBL] [Abstract][Full Text] [Related]
15. Establishment of liver specific glucokinase gene knockout mice: a new animal model for screening anti-diabetic drugs. Zhang YL; Tan XH; Xiao MF; Li H; Mao YQ; Yang X; Tan HR Acta Pharmacol Sin; 2004 Dec; 25(12):1659-65. PubMed ID: 15569412 [TBL] [Abstract][Full Text] [Related]
16. Characterization of glucokinase mutations associated with maturity-onset diabetes of the young type 2 (MODY-2): different glucokinase defects lead to a common phenotype. Miller SP; Anand GR; Karschnia EJ; Bell GI; LaPorte DC; Lange AJ Diabetes; 1999 Aug; 48(8):1645-51. PubMed ID: 10426385 [TBL] [Abstract][Full Text] [Related]
17. Human glucokinase gene: isolation, structural characterization, and identification of a microsatellite repeat polymorphism. Tanizawa Y; Matsutani A; Chiu KC; Permutt MA Mol Endocrinol; 1992 Jul; 6(7):1070-81. PubMed ID: 1354840 [TBL] [Abstract][Full Text] [Related]
18. Structural instability of mutant beta-cell glucokinase: implications for the molecular pathogenesis of maturity-onset diabetes of the young (type-2). Kesavan P; Wang L; Davis E; Cuesta A; Sweet I; Niswender K; Magnuson MA; Matschinsky FM Biochem J; 1997 Feb; 322 ( Pt 1)(Pt 1):57-63. PubMed ID: 9078243 [TBL] [Abstract][Full Text] [Related]