These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 9057869)

  • 1. Nonsteroidal anti-inflammatory drugs as scaffolds for the design of 5-lipoxygenase inhibitors.
    Kolasa T; Brooks CD; Rodriques KE; Summers JB; Dellaria JF; Hulkower KI; Bouska J; Bell RL; Carter GW
    J Med Chem; 1997 Feb; 40(5):819-24. PubMed ID: 9057869
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dibenzoxepinone hydroxylamines and hydroxamic acids: dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity.
    Hamer RR; Tegeler JJ; Kurtz ES; Allen RC; Bailey SC; Elliott ME; Hellyer L; Helsley GC; Przekop P; Freed BS; White J; Martin LL
    J Med Chem; 1996 Jan; 39(1):246-52. PubMed ID: 8568814
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile.
    Argentieri DC; Ritchie DM; Ferro MP; Kirchner T; Wachter MP; Anderson DW; Rosenthale ME; Capetola RJ
    J Pharmacol Exp Ther; 1994 Dec; 271(3):1399-408. PubMed ID: 7996452
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of celecoxib analogues possessing a N-difluoromethyl-1,2-dihydropyrid-2-one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
    J Med Chem; 2009 Mar; 52(6):1525-9. PubMed ID: 19296694
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6138-41. PubMed ID: 18945614
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats.
    Lesch CA; Gilbertsen RB; Song Y; Dyer RD; Schrier D; Kraus ER; Sanchez B; Guglietta A
    J Pharmacol Exp Ther; 1998 Oct; 287(1):301-6. PubMed ID: 9765350
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conversion of a cyclooxygenase (CO) inhibitor into a 5-lipoxygenase (LO) inhibitor: a general route to novel orally active anti-inflammatory and anti-allergy drugs.
    Kreft AF; Failli AA; Musser JH; Kubrak DM; Banker AL; Steffan R; Demerson CA; Nelson JA; Shah US; Gray W
    Drugs Exp Clin Res; 1991; 17(8):381-7. PubMed ID: 1822830
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [2-Aryl-pyrrolo[2,1-b]benzothiazoles as a selective or dual inhibitors of cyclo-oxygenases and 5-lipoxygenases. 21. Non-steroidal anti-inflammatory agents].
    Dannhardt G; Kreher M; Nowe U; Schmitt S
    Pharmazie; 1997 Jun; 52(6):428-36. PubMed ID: 9324689
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
    Velázquez C; Praveen Rao PN; Knaus EE
    J Med Chem; 2005 Jun; 48(12):4061-7. PubMed ID: 15943479
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones.
    Bhatia PA; Brooks CD; Basha A; Ratajczyk JD; Gunn BP; Bouska JB; Lanni C; Young PR; Bell RL; Carter GW
    J Med Chem; 1996 Sep; 39(20):3938-50. PubMed ID: 8831760
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Adamantane derivatives of thiazolyl-N-substituted amide, as possible non-steroidal anti-inflammatory agents.
    Kouatly O; Geronikaki A; Kamoutsis C; Hadjipavlou-Litina D; Eleftheriou P
    Eur J Med Chem; 2009 Mar; 44(3):1198-204. PubMed ID: 18603333
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation.
    Kirchner T; Argentieri DC; Barbone AG; Singer M; Steber M; Ansell J; Beers SA; Wachter MP; Wu W; Malloy E; Stewart A; Ritchie DM
    J Pharmacol Exp Ther; 1997 Aug; 282(2):1094-101. PubMed ID: 9262379
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of (2-fluoro-benzyl)-(2-methyl-2-phenethyl-2H-chromen-6-yl)-amine (KRH-102140) as an orally active 5-lipoxygenase inhibitor with activity in murine inflammation models.
    Cho YS; Song JS; Huh JY; Kim CH; Gong YD; Cheon HG
    Pharmacology; 2011; 87(1-2):49-55. PubMed ID: 21212714
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Non-steroidal antiinflammatory agents. Synthesis and enzyme inhibition of 2-[4-(heteroarylmethyl)phenyl] propanoic acids and analogues.
    Silvestri R; Pagnozzi E; Valoti M; Fusi F
    Farmaco; 1994 Oct; 49(10):625-32. PubMed ID: 7826468
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modified acidic nonsteroidal anti-inflammatory drugs as dual inhibitors of mPGES-1 and 5-LOX.
    Elkady M; Nieß R; Schaible AM; Bauer J; Luderer S; Ambrosi G; Werz O; Laufer SA
    J Med Chem; 2012 Oct; 55(20):8958-62. PubMed ID: 22992107
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and biological evaluation of substituted 2-alkylthio-1,5-diarylimidazoles as selective COX-2 inhibitors.
    Navidpour L; Shadnia H; Shafaroodi H; Amini M; Dehpour AR; Shafiee A
    Bioorg Med Chem; 2007 Mar; 15(5):1976-82. PubMed ID: 17258905
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities.
    Jahng Y; Zhao LX; Moon YS; Basnet A; Kim EK; Chang HW; Ju HK; Jeong TC; Lee ES
    Bioorg Med Chem Lett; 2004 May; 14(10):2559-62. PubMed ID: 15109651
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and anti-inflammatory activity of chalcone derivatives.
    Herencia F; Ferrándiz ML; Ubeda A; Domínguez JN; Charris JE; Lobo GM; Alcaraz MJ
    Bioorg Med Chem Lett; 1998 May; 8(10):1169-74. PubMed ID: 9871729
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of 1-(methanesulfonyl- and aminosulfonylphenyl)acetylenes that possess a 2-(N-difluoromethyl-1,2-dihydropyridin-2-one) pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Rahman M; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2009 Feb; 19(3):584-8. PubMed ID: 19136259
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of potential anti-inflammatory drugs: diaryl-1,2,4-triazoles bearing N-hydroxyurea moiety as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.
    Jiang B; Huang X; Yao H; Jiang J; Wu X; Jiang S; Wang Q; Lu T; Xu J
    Org Biomol Chem; 2014 Apr; 12(13):2114-27. PubMed ID: 24562695
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.