BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 9083002)

  • 1. A familial amyotrophic lateral sclerosis-associated A4V Cu, Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value.
    Yim HS; Kang JH; Chock PB; Stadtman ER; Yim MB
    J Biol Chem; 1997 Apr; 272(14):8861-3. PubMed ID: 9083002
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide.
    Yim MB; Kang JH; Yim HS; Kwak HS; Chock PB; Stadtman ER
    Proc Natl Acad Sci U S A; 1996 Jun; 93(12):5709-14. PubMed ID: 8650157
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Release of copper ions from the familial amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutants.
    Eum WS; Kang JH
    Mol Cells; 1999 Feb; 9(1):110-4. PubMed ID: 10102580
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced free radical generation of FALS-associated Cu,Zn-SOD mutants.
    Yim MB; Yim HS; Chock PB; Stadtman ER
    Neurotox Res; 1999 Dec; 1(2):91-7. PubMed ID: 12835105
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression, purification, and characterization of a familial amyotrophic lateral sclerosis-associated D90A Cu,Zn-superoxide dismutase mutant.
    Kim SM; Eum WS; Kang JH
    Mol Cells; 1998 Aug; 8(4):478-82. PubMed ID: 9749537
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced oxidative damage by the familial amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutants.
    Kang JH; Eum WS
    Biochim Biophys Acta; 2000 Dec; 1524(2-3):162-70. PubMed ID: 11113563
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The free radical-generating function of a familial amyotrophic lateral sclerosis-associated D90A Cu,Zn-superoxide dismutase mutant.
    Kim SM; Eum WS; Kwon OB; Kang JH
    Biochem Mol Biol Int; 1998 Dec; 46(6):1191-200. PubMed ID: 9891852
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gain in functions of mutant Cu,Zn-superoxide dismutases as a causative factor in familial amyotrophic lateral sclerosis: less reactive oxidant formation but high spontaneous aggregation and precipitation.
    Okado-Matsumoto A; Myint T; Fujii J; Taniguchi N
    Free Radic Res; 2000 Jul; 33(1):65-73. PubMed ID: 10826922
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase.
    Cardoso RM; Thayer MM; DiDonato M; Lo TP; Bruns CK; Getzoff ED; Tainer JA
    J Mol Biol; 2002 Nov; 324(2):247-56. PubMed ID: 12441104
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo peroxidative activity of FALS-mutant human CuZnSODs expressed in yeast.
    Roe JA; Wiedau-Pazos M; Moy VN; Goto JJ; Gralla EB; Valentine JS
    Free Radic Biol Med; 2002 Jan; 32(2):169-74. PubMed ID: 11796206
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glycation proceeds faster in mutated Cu, Zn-superoxide dismutases related to familial amyotrophic lateral sclerosis.
    Takamiya R; Takahashi M; Myint T; Park YS; Miyazawa N; Endo T; Fujiwara N; Sakiyama H; Misonou Y; Miyamoto Y; Fujii J; Taniguchi N
    FASEB J; 2003 May; 17(8):938-40. PubMed ID: 12626432
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reexamination of the mechanism of hydroxyl radical adducts formed from the reaction between familial amyotrophic lateral sclerosis-associated Cu,Zn superoxide dismutase mutants and H2O2.
    Singh RJ; Karoui H; Gunther MR; Beckman JS; Mason RP; Kalyanaraman B
    Proc Natl Acad Sci U S A; 1998 Jun; 95(12):6675-80. PubMed ID: 9618471
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis.
    Wiedau-Pazos M; Goto JJ; Rabizadeh S; Gralla EB; Roe JA; Lee MK; Valentine JS; Bredesen DE
    Science; 1996 Jan; 271(5248):515-8. PubMed ID: 8560268
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stabilization of mutant Cu/Zn superoxide dismutase (SOD1) protein by coexpressed wild SOD1 protein accelerates the disease progression in familial amyotrophic lateral sclerosis mice.
    Fukada K; Nagano S; Satoh M; Tohyama C; Nakanishi T; Shimizu A; Yanagihara T; Sakoda S
    Eur J Neurosci; 2001 Dec; 14(12):2032-6. PubMed ID: 11860498
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis.
    Bowling AC; Barkowski EE; McKenna-Yasek D; Sapp P; Horvitz HR; Beal MF; Brown RH
    J Neurochem; 1995 May; 64(5):2366-9. PubMed ID: 7722523
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reactions of hydrogen peroxide with familial amyotrophic lateral sclerosis mutant human copper-zinc superoxide dismutases studied by pulse radiolysis.
    Goto JJ; Gralla EB; Valentine JS; Cabelli DE
    J Biol Chem; 1998 Nov; 273(46):30104-9. PubMed ID: 9804764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dynamic properties of the G93A mutant of copper-zinc superoxide dismutase as detected by NMR spectroscopy: implications for the pathology of familial amyotrophic lateral sclerosis.
    Shipp EL; Cantini F; Bertini I; Valentine JS; Banci L
    Biochemistry; 2003 Feb; 42(7):1890-9. PubMed ID: 12590575
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Accelerated s-nitrosothiol breakdown by amyotrophic lateral sclerosis mutant copper,zinc-superoxide dismutase.
    Johnson MA; Macdonald TL; Mannick JB; Conaway MR; Gaston B
    J Biol Chem; 2001 Oct; 276(43):39872-8. PubMed ID: 11518706
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The familial amyotrophic lateral sclerosis-associated amino acid substitutions E100G, G93A, and G93R do not influence the rate of inactivation of copper- and zinc-containing superoxide dismutase by H2O2.
    Liochev SI; Chen LL; Hallewell RA; Fridovich I
    Arch Biochem Biophys; 1998 Apr; 352(2):237-9. PubMed ID: 9587411
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of three mutations in the Cu,Zn-superoxide dismutase (Cu,Zn-SOD) gene with familial amyotrophic lateral sclerosis: transduction of human Cu,Zn-SOD into PC12 cells by HIV-1 TAT protein basic domain.
    Chou CM; Huang CJ; Shih CM; Chen YP; Liu TP; Chen CT
    Ann N Y Acad Sci; 2005 May; 1042():303-13. PubMed ID: 15965076
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.