BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 9083103)

  • 1. Functional importance of Shc tyrosine 317 on insulin signaling in Rat1 fibroblasts expressing insulin receptors.
    Ishihara H; Sasaoka T; Ishiki M; Takata Y; Imamura T; Usui I; Langlois WJ; Sawa T; Kobayashi M
    J Biol Chem; 1997 Apr; 272(14):9581-6. PubMed ID: 9083103
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Relative involvement of Shc tyrosine 239/240 and tyrosine 317 on insulin induced mitogenic signaling in rat1 fibroblasts expressing insulin receptors.
    Ishihara H; Sasaoka T; Wada T; Ishiki M; Haruta T; Usui I; Iwata M; Takano A; Uno T; Ueno E; Kobayashi M
    Biochem Biophys Res Commun; 1998 Nov; 252(1):139-44. PubMed ID: 9813159
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional importance of amino-terminal domain of Shc for interaction with insulin and epidermal growth factor receptors in phosphorylation-independent manner.
    Sasaoka T; Ishihara H; Sawa T; Ishiki M; Morioka H; Imamura T; Usui I; Takata Y; Kobayashi M
    J Biol Chem; 1996 Aug; 271(33):20082-7. PubMed ID: 8702728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of the Src homology 2 (SH2) domain and C-terminus tyrosine phosphorylation sites of SH2-containing inositol phosphatase (SHIP) in the regulation of insulin-induced mitogenesis.
    Wada T; Sasaoka T; Ishiki M; Hori H; Haruta T; Ishihara H; Kobayashi M
    Endocrinology; 1999 Oct; 140(10):4585-94. PubMed ID: 10499514
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of the insulin and insulin-like growth factor 1 mitogenic intracellular signaling pathways.
    Sasaoka T; Ishiki M; Sawa T; Ishihara H; Takata Y; Imamura T; Usui I; Olefsky JM; Kobayashi M
    Endocrinology; 1996 Oct; 137(10):4427-34. PubMed ID: 8828504
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation.
    Sasaoka T; Draznin B; Leitner JW; Langlois WJ; Olefsky JM
    J Biol Chem; 1994 Apr; 269(14):10734-8. PubMed ID: 8144662
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events.
    Schlaepfer DD; Jones KC; Hunter T
    Mol Cell Biol; 1998 May; 18(5):2571-85. PubMed ID: 9566877
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Membrane localization of Src homology 2-containing inositol 5'-phosphatase 2 via Shc association is required for the negative regulation of insulin signaling in Rat1 fibroblasts overexpressing insulin receptors.
    Ishihara H; Sasaoka T; Ishiki M; Wada T; Hori H; Kagawa S; Kobayashi M
    Mol Endocrinol; 2002 Oct; 16(10):2371-81. PubMed ID: 12351701
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tyrosine phosphorylation-dependent and -independent role of Shc in the regulation of IGF-1-induced mitogenesis and glycogen synthesis.
    Sasaoka T; Ishiki M; Wada T; Hori H; Hirai H; Haruta T; Ishihara H; Kobayashi M
    Endocrinology; 2001 Dec; 142(12):5226-35. PubMed ID: 11713219
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors.
    Inoue G; Cheatham B; Kahn CR
    J Biol Chem; 1996 Nov; 271(45):28206-11. PubMed ID: 8910437
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Roles of insulin receptor substrate-1 and Shc on insulin-like growth factor I receptor signaling in early passages of cultured human fibroblasts.
    Takahashi Y; Tobe K; Kadowaki H; Katsumata D; Fukushima Y; Yazaki Y; Akanuma Y; Kadowaki T
    Endocrinology; 1997 Feb; 138(2):741-50. PubMed ID: 9003010
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signaling.
    Kim B; Cheng HL; Margolis B; Feldman EL
    J Biol Chem; 1998 Dec; 273(51):34543-50. PubMed ID: 9852124
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Association between GRB2/Sos and insulin receptor substrate 1 is not sufficient for activation of extracellular signal-regulated kinases by interleukin-4: implications for Ras activation by insulin.
    Pruett W; Yuan Y; Rose E; Batzer AG; Harada N; Skolnik EY
    Mol Cell Biol; 1995 Mar; 15(3):1778-85. PubMed ID: 7862167
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intracellular signalling pathways of okadaic acid leading to mitogenesis in Rat1 fibroblast overexpressing insulin receptors: okadaic acid regulates Shc phosphorylation by mechanisms independent of insulin.
    Sawa T; Sasaoka T; Hirai H; Ishihara H; Ishiki M; Wada T; Kobayashi M
    Cell Signal; 1999 Nov; 11(11):797-803. PubMed ID: 10617282
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insulin signals to prenyltransferases via the Shc branch of intracellular signaling.
    Goalstone ML; Leitner JW; Berhanu P; Sharma PM; Olefsky JM; Draznin B
    J Biol Chem; 2001 Apr; 276(16):12805-12. PubMed ID: 11278505
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Src-family tyrosine kinases in activation of ERK-1 and p85/p110-phosphatidylinositol 3-kinase by G/CCKB receptors.
    Daulhac L; Kowalski-Chauvel A; Pradayrol L; Vaysse N; Seva C
    J Biol Chem; 1999 Jul; 274(29):20657-63. PubMed ID: 10400698
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin receptor substrate-1 enhances growth hormone-induced proliferation.
    Liang L; Zhou T; Jiang J; Pierce JH; Gustafson TA; Frank SJ
    Endocrinology; 1999 May; 140(5):1972-83. PubMed ID: 10218944
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential role of insulin receptor substrate (IRS)-1 and IRS-2 in L6 skeletal muscle cells expressing the Arg1152 --> Gln insulin receptor.
    Miele C; Caruso M; Calleja V; Auricchio R; Oriente F; Formisano P; Condorelli G; Cafieri A; Sawka-Verhelle D; Van Obberghen E; Beguinot F
    J Biol Chem; 1999 Jan; 274(5):3094-102. PubMed ID: 9915848
    [TBL] [Abstract][Full Text] [Related]  

  • 19. G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases.
    Luttrell LM; Daaka Y; Della Rocca GJ; Lefkowitz RJ
    J Biol Chem; 1997 Dec; 272(50):31648-56. PubMed ID: 9395506
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Growth hormone stimulates the tyrosine kinase activity of JAK2 and induces tyrosine phosphorylation of insulin receptor substrates and Shc in rat tissues.
    Thirone AC; Carvalho CR; Saad MJ
    Endocrinology; 1999 Jan; 140(1):55-62. PubMed ID: 9886807
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.