306 related articles for article (PubMed ID: 9083481)
1. Discovery of HIV-1 integrase inhibitors by pharmacophore searching.
Hong H; Neamati N; Wang S; Nicklaus MC; Mazumder A; Zhao H; Burke TR; Pommier Y; Milne GW
J Med Chem; 1997 Mar; 40(6):930-6. PubMed ID: 9083481
[TBL] [Abstract][Full Text] [Related]
2. Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.
Neamati N; Hong H; Mazumder A; Wang S; Sunder S; Nicklaus MC; Milne GW; Proksa B; Pommier Y
J Med Chem; 1997 Mar; 40(6):942-51. PubMed ID: 9083483
[TBL] [Abstract][Full Text] [Related]
3. HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching.
Nicklaus MC; Neamati N; Hong H; Mazumder A; Sunder S; Chen J; Milne GW; Pommier Y
J Med Chem; 1997 Mar; 40(6):920-9. PubMed ID: 9083480
[TBL] [Abstract][Full Text] [Related]
4. Efficient 3D database screening for novel HIV-1 IN inhibitors.
Barreca ML; Rao A; De Luca L; ZappalĂ M; Gurnari C; Monforte P; De Clercq E; Van Maele B; Debyser Z; Witvrouw M; Briggs JM; Chimirri A
J Chem Inf Comput Sci; 2004; 44(4):1450-5. PubMed ID: 15272853
[TBL] [Abstract][Full Text] [Related]
5. Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
Dayam R; Sanchez T; Neamati N
J Med Chem; 2005 Dec; 48(25):8009-15. PubMed ID: 16335925
[TBL] [Abstract][Full Text] [Related]
6. Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore.
Deng J; Sanchez T; Al-Mawsawi LQ; Dayam R; Yunes RA; Garofalo A; Bolger MB; Neamati N
Bioorg Med Chem; 2007 Jul; 15(14):4985-5002. PubMed ID: 17502148
[TBL] [Abstract][Full Text] [Related]
7. Hydrazide-containing inhibitors of HIV-1 integrase.
Zhao H; Neamati N; Sunder S; Hong H; Wang S; Milne GW; Pommier Y; Burke TR
J Med Chem; 1997 Mar; 40(6):937-41. PubMed ID: 9083482
[TBL] [Abstract][Full Text] [Related]
8. Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.
Dayam R; Sanchez T; Clement O; Shoemaker R; Sei S; Neamati N
J Med Chem; 2005 Jan; 48(1):111-20. PubMed ID: 15634005
[TBL] [Abstract][Full Text] [Related]
9. A platform for designing HIV integrase inhibitors. Part 1: 2-hydroxy-3-heteroaryl acrylic acid derivatives as novel HIV integrase inhibitor and modeling of hydrophilic and hydrophobic pharmacophores.
Kawasuji T; Yoshinaga T; Sato A; Yodo M; Fujiwara T; Kiyama R
Bioorg Med Chem; 2006 Dec; 14(24):8430-45. PubMed ID: 17010623
[TBL] [Abstract][Full Text] [Related]
10. Salicylhydrazine-containing inhibitors of HIV-1 integrase: implication for a selective chelation in the integrase active site.
Neamati N; Hong H; Owen JM; Sunder S; Winslow HE; Christensen JL; Zhao H; Burke TR; Milne GW; Pommier Y
J Med Chem; 1998 Aug; 41(17):3202-9. PubMed ID: 9703465
[TBL] [Abstract][Full Text] [Related]
11. Triketoacid inhibitors of HIV-integrase: a new chemotype useful for probing the integrase pharmacophore.
Walker MA; Johnson T; Ma Z; Banville J; Remillard R; Kim O; Zhang Y; Staab A; Wong H; Torri A; Samanta H; Lin Z; Deminie C; Terry B; Krystal M; Meanwell N
Bioorg Med Chem Lett; 2006 Jun; 16(11):2920-4. PubMed ID: 16546383
[TBL] [Abstract][Full Text] [Related]
12. Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase.
Ma K; Wang P; Fu W; Wan X; Zhou L; Chu Y; Ye D
Bioorg Med Chem Lett; 2011 Nov; 21(22):6724-7. PubMed ID: 21996518
[TBL] [Abstract][Full Text] [Related]
13. Dynamic pharmacophore model optimization: identification of novel HIV-1 integrase inhibitors.
Deng J; Sanchez T; Neamati N; Briggs JM
J Med Chem; 2006 Mar; 49(5):1684-92. PubMed ID: 16509584
[TBL] [Abstract][Full Text] [Related]
14. Mining the NCI antiviral compounds for HIV-1 integrase inhibitors.
Deng J; Kelley JA; Barchi JJ; Sanchez T; Dayam R; Pommier Y; Neamati N
Bioorg Med Chem; 2006 Jun; 14(11):3785-92. PubMed ID: 16460953
[TBL] [Abstract][Full Text] [Related]
15. Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action.
Mazumder A; Neamati N; Sunder S; Schulz J; Pertz H; Eich E; Pommier Y
J Med Chem; 1997 Sep; 40(19):3057-63. PubMed ID: 9301668
[TBL] [Abstract][Full Text] [Related]
16. HIV-1 integrase pharmacophore model derived from diverse classes of inhibitors.
Mustata GI; Brigo A; Briggs JM
Bioorg Med Chem Lett; 2004 Mar; 14(6):1447-54. PubMed ID: 15006380
[TBL] [Abstract][Full Text] [Related]
17. Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.
De Luca L; Barreca ML; Ferro S; Christ F; Iraci N; Gitto R; Monforte AM; Debyser Z; Chimirri A
ChemMedChem; 2009 Aug; 4(8):1311-6. PubMed ID: 19565598
[TBL] [Abstract][Full Text] [Related]
18. Discovery of HIV-1 integrase inhibitors: pharmacophore mapping, virtual screening, molecular docking, synthesis, and biological evaluation.
Bhatt H; Patel P; Pannecouque C
Chem Biol Drug Des; 2014 Feb; 83(2):154-66. PubMed ID: 23957390
[TBL] [Abstract][Full Text] [Related]
19. Discovery and structure-activity relationship studies of a unique class of HIV-1 integrase inhibitors.
Dayam R; Sanchez T; Neamati N
ChemMedChem; 2006 Feb; 1(2):238-44. PubMed ID: 16892356
[TBL] [Abstract][Full Text] [Related]
20. Dynamic receptor-based pharmacophore model development and its application in designing novel HIV-1 integrase inhibitors.
Deng J; Lee KW; Sanchez T; Cui M; Neamati N; Briggs JM
J Med Chem; 2005 Mar; 48(5):1496-505. PubMed ID: 15743192
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]