BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

583 related articles for article (PubMed ID: 9087425)

  • 1. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.
    Kennedy SG; Wagner AJ; Conzen SD; Jordán J; Bellacosa A; Tsichlis PN; Hay N
    Genes Dev; 1997 Mar; 11(6):701-13. PubMed ID: 9087425
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation.
    King WG; Mattaliano MD; Chan TO; Tsichlis PN; Brugge JS
    Mol Cell Biol; 1997 Aug; 17(8):4406-18. PubMed ID: 9234699
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.
    Kauffmann-Zeh A; Rodriguez-Viciana P; Ulrich E; Gilbert C; Coffer P; Downward J; Evan G
    Nature; 1997 Feb; 385(6616):544-8. PubMed ID: 9020362
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway.
    Khwaja A; Rodriguez-Viciana P; Wennström S; Warne PH; Downward J
    EMBO J; 1997 May; 16(10):2783-93. PubMed ID: 9184223
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.
    Kulik G; Klippel A; Weber MJ
    Mol Cell Biol; 1997 Mar; 17(3):1595-606. PubMed ID: 9032287
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase.
    Franke TF; Yang SI; Chan TO; Datta K; Kazlauskas A; Morrison DK; Kaplan DR; Tsichlis PN
    Cell; 1995 Jun; 81(5):727-36. PubMed ID: 7774014
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neurons.
    Orike N; Middleton G; Borthwick E; Buchman V; Cowen T; Davies AM
    J Cell Biol; 2001 Sep; 154(5):995-1005. PubMed ID: 11524433
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of PI3-kinase/PKB contributes to delay in neutrophil apoptosis after thermal injury.
    Hu Z; Sayeed MM
    Am J Physiol Cell Physiol; 2005 May; 288(5):C1171-8. PubMed ID: 15625305
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase.
    Didichenko SA; Tilton B; Hemmings BA; Ballmer-Hofer K; Thelen M
    Curr Biol; 1996 Oct; 6(10):1271-8. PubMed ID: 8939574
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line.
    Eves EM; Xiong W; Bellacosa A; Kennedy SG; Tsichlis PN; Rosner MR; Hay N
    Mol Cell Biol; 1998 Apr; 18(4):2143-52. PubMed ID: 9528786
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.
    O'Gorman DM; McKenna SL; McGahon AJ; Knox KA; Cotter TG
    Leukemia; 2000 Apr; 14(4):602-11. PubMed ID: 10764145
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction.
    Burgering BM; Coffer PJ
    Nature; 1995 Aug; 376(6541):599-602. PubMed ID: 7637810
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.
    Crowder RJ; Freeman RS
    J Neurosci; 1998 Apr; 18(8):2933-43. PubMed ID: 9526010
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt.
    del Peso L; González-García M; Page C; Herrera R; Nuñez G
    Science; 1997 Oct; 278(5338):687-9. PubMed ID: 9381178
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Akt is activated in response to an apoptotic signal.
    Tang D; Okada H; Ruland J; Liu L; Stambolic V; Mak TW; Ingram AJ
    J Biol Chem; 2001 Aug; 276(32):30461-6. PubMed ID: 11399756
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G; Sailaja D
    Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3577-88. PubMed ID: 15452065
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras.
    van Weering DH; de Rooij J; Marte B; Downward J; Bos JL; Burgering BM
    Mol Cell Biol; 1998 Apr; 18(4):1802-11. PubMed ID: 9528752
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Requirement of phosphatidylinositol 3-kinase-dependent pathway and Src for Gas6-Axl mitogenic and survival activities in NIH 3T3 fibroblasts.
    Goruppi S; Ruaro E; Varnum B; Schneider C
    Mol Cell Biol; 1997 Aug; 17(8):4442-53. PubMed ID: 9234702
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members.
    Limaye V; Li X; Hahn C; Xia P; Berndt MC; Vadas MA; Gamble JR
    Blood; 2005 Apr; 105(8):3169-77. PubMed ID: 15632208
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hyaluronan activates cell motility of v-Src-transformed cells via Ras-mitogen-activated protein kinase and phosphoinositide 3-kinase-Akt in a tumor-specific manner.
    Sohara Y; Ishiguro N; Machida K; Kurata H; Thant AA; Senga T; Matsuda S; Kimata K; Iwata H; Hamaguchi M
    Mol Biol Cell; 2001 Jun; 12(6):1859-68. PubMed ID: 11408591
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.