BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 9092631)

  • 1. Specificity and kinetics of interstrand and intrastrand bifunctional alkylation by nitrogen mustards at a G-G-C sequence.
    Bauer GB; Povirk LF
    Nucleic Acids Res; 1997 Mar; 25(6):1211-8. PubMed ID: 9092631
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA damage and mutagenesis induced by nitrogen mustards.
    Povirk LF; Shuker DE
    Mutat Res; 1994 Dec; 318(3):205-26. PubMed ID: 7527485
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA sequence analysis of mutations induced by melphalan in the CHO aprt locus.
    Austin MJ; Han YH; Povirk LF
    Cancer Genet Cytogenet; 1992 Nov; 64(1):69-74. PubMed ID: 1458453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thermolabile adenine adducts and A.T base pair substitutions induced by nitrogen mustard analogues in an SV40-based shuttle plasmid.
    Wang P; Bauer GB; Bennett RA; Povirk LF
    Biochemistry; 1991 Dec; 30(49):11515-21. PubMed ID: 1660721
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.
    Mattes WB; Hartley JA; Kohn KW
    Nucleic Acids Res; 1986 Apr; 14(7):2971-87. PubMed ID: 3960738
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The mechanism of guanine alkylation by nitrogen mustards: a computational study.
    Polavarapu A; Stillabower JA; Stubblefield SG; Taylor WM; Baik MH
    J Org Chem; 2012 Jul; 77(14):5914-21. PubMed ID: 22681226
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards.
    Balcome S; Park S; Quirk Dorr DR; Hafner L; Phillips L; Tretyakova N
    Chem Res Toxicol; 2004 Jul; 17(7):950-62. PubMed ID: 15257621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA adenine adducts induced by nitrogen mustards and their role in transcription termination in vitro.
    Pieper RO; Erickson LC
    Carcinogenesis; 1990 Oct; 11(10):1739-46. PubMed ID: 2208589
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA interstrand crosslink formation by mechlorethamine at a cytosine-cytosine mismatch pair: kinetics and sequence dependence.
    Romero RM; Rojsitthisak P; Haworth IS
    Arch Biochem Biophys; 2001 Feb; 386(2):143-53. PubMed ID: 11368336
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular dynamics simulations of chlorambucil/DNA adducts. A structural basis for the 5'-GNC interstrand DNA crosslink formed by nitrogen mustards.
    Remias MG; Lee CS; Haworth IS
    J Biomol Struct Dyn; 1995 Feb; 12(4):911-36. PubMed ID: 7779307
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC).
    Dong Q; Barsky D; Colvin ME; Melius CF; Ludeman SM; Moravek JF; Colvin OM; Bigner DD; Modrich P; Friedman HS
    Proc Natl Acad Sci U S A; 1995 Dec; 92(26):12170-4. PubMed ID: 8618865
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cross-linking of the DNA repair protein Omicron6-alkylguanine DNA alkyltransferase to DNA in the presence of antitumor nitrogen mustards.
    Loeber R; Michaelson E; Fang Q; Campbell C; Pegg AE; Tretyakova N
    Chem Res Toxicol; 2008 Apr; 21(4):787-95. PubMed ID: 18324787
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of a duplex oligonucleotide containing a nitrogen mustard interstrand DNA-DNA cross-link.
    Ojwang JO; Grueneberg DA; Loechler EL
    Cancer Res; 1989 Dec; 49(23):6529-37. PubMed ID: 2819709
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sequence specificity of alkylation for a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size: evidence for increased cytotoxicity with enhanced sequence specificity.
    Wyatt MD; Lee M; Garbiras BJ; Souhami RL; Hartley JA
    Biochemistry; 1995 Oct; 34(40):13034-41. PubMed ID: 7548062
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A New Cross-Link for an Old Cross-Linking Drug: The Nitrogen Mustard Anticancer Agent Mechlorethamine Generates Cross-Links Derived from Abasic Sites in Addition to the Expected Drug-Bridged Cross-Links.
    Nejad MI; Johnson KM; Price NE; Gates KS
    Biochemistry; 2016 Dec; 55(50):7033-7041. PubMed ID: 27992994
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards.
    Wang F; Li F; Ganguly M; Marky LA; Gold B; Egli M; Stone MP
    Biochemistry; 2008 Jul; 47(27):7147-57. PubMed ID: 18549246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
    McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
    Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative pharmacokinetics of DNA lesion formation and removal following treatment of L1210 cells with nitrogen mustards.
    O'Connor PM; Kohn KW
    Cancer Commun; 1990; 2(12):387-94. PubMed ID: 2265064
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and reactivity of aryl nitrogen mustard-oligodeoxyribonucleotide conjugates.
    Reed MW; Lukhtanov EA; Gorn V; Kutyavin I; Gall A; Wald A; Meyer RB
    Bioconjug Chem; 1998; 9(1):64-71. PubMed ID: 9460548
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The cytotoxicity, DNA crosslinking ability and DNA sequence selectivity of the aniline mustards melphalan, chlorambucil and 4-[bis(2-chloroethyl)amino] benzoic acid.
    Sunters A; Springer CJ; Bagshawe KD; Souhami RL; Hartley JA
    Biochem Pharmacol; 1992 Jul; 44(1):59-64. PubMed ID: 1632839
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.