1328 related articles for article (PubMed ID: 9094314)
1. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha.
Alessi DR; James SR; Downes CP; Holmes AB; Gaffney PR; Reese CB; Cohen P
Curr Biol; 1997 Apr; 7(4):261-9. PubMed ID: 9094314
[TBL] [Abstract][Full Text] [Related]
2. 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.
Alessi DR; Deak M; Casamayor A; Caudwell FB; Morrice N; Norman DG; Gaffney P; Reese CB; MacDougall CN; Harbison D; Ashworth A; Bownes M
Curr Biol; 1997 Oct; 7(10):776-89. PubMed ID: 9368760
[TBL] [Abstract][Full Text] [Related]
3. PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.
Balendran A; Casamayor A; Deak M; Paterson A; Gaffney P; Currie R; Downes CP; Alessi DR
Curr Biol; 1999 Apr; 9(8):393-404. PubMed ID: 10226025
[TBL] [Abstract][Full Text] [Related]
4. Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.
Currie RA; Walker KS; Gray A; Deak M; Casamayor A; Downes CP; Cohen P; Alessi DR; Lucocq J
Biochem J; 1999 Feb; 337 ( Pt 3)(Pt 3):575-83. PubMed ID: 9895304
[TBL] [Abstract][Full Text] [Related]
5. Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2.
Kobayashi T; Cohen P
Biochem J; 1999 Apr; 339 ( Pt 2)(Pt 2):319-28. PubMed ID: 10191262
[TBL] [Abstract][Full Text] [Related]
6. Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.
Walker KS; Deak M; Paterson A; Hudson K; Cohen P; Alessi DR
Biochem J; 1998 Apr; 331 ( Pt 1)(Pt 1):299-308. PubMed ID: 9512493
[TBL] [Abstract][Full Text] [Related]
7. Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B.
Rena G; Guo S; Cichy SC; Unterman TG; Cohen P
J Biol Chem; 1999 Jun; 274(24):17179-83. PubMed ID: 10358075
[TBL] [Abstract][Full Text] [Related]
8. Tumour necrosis factor-alpha activation of protein kinase B in WEHI-164 cells is accompanied by increased phosphorylation of Ser473, but not Thr308.
O'toole A; Moule SK; Lockyer PJ; Halestrap AP
Biochem J; 2001 Oct; 359(Pt 1):119-27. PubMed ID: 11563975
[TBL] [Abstract][Full Text] [Related]
9. Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B.
Stephens L; Anderson K; Stokoe D; Erdjument-Bromage H; Painter GF; Holmes AB; Gaffney PR; Reese CB; McCormick F; Tempst P; Coadwell J; Hawkins PT
Science; 1998 Jan; 279(5351):710-4. PubMed ID: 9445477
[TBL] [Abstract][Full Text] [Related]
10. 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro.
Alessi DR; Kozlowski MT; Weng QP; Morrice N; Avruch J
Curr Biol; 1998 Jan; 8(2):69-81. PubMed ID: 9427642
[TBL] [Abstract][Full Text] [Related]
11. Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase.
Andjelković M; Maira SM; Cron P; Parker PJ; Hemmings BA
Mol Cell Biol; 1999 Jul; 19(7):5061-72. PubMed ID: 10373555
[TBL] [Abstract][Full Text] [Related]
12. PDK1, one of the missing links in insulin signal transduction?
Cohen P; Alessi DR; Cross DA
FEBS Lett; 1997 Jun; 410(1):3-10. PubMed ID: 9247112
[TBL] [Abstract][Full Text] [Related]
13. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B.
Scheid MP; Marignani PA; Woodgett JR
Mol Cell Biol; 2002 Sep; 22(17):6247-60. PubMed ID: 12167717
[TBL] [Abstract][Full Text] [Related]
14. Peroxovanadate induces tyrosine phosphorylation of phosphoinositide-dependent protein kinase-1 potential involvement of src kinase.
Grillo S; Grémeaux T; Casamayor A; Alessi DR; Le Marchand-Brustel Y; Tanti JF
Eur J Biochem; 2000 Nov; 267(22):6642-9. PubMed ID: 11054117
[TBL] [Abstract][Full Text] [Related]
15. The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells.
Williams MR; Arthur JS; Balendran A; van der Kaay J; Poli V; Cohen P; Alessi DR
Curr Biol; 2000 Apr; 10(8):439-48. PubMed ID: 10801415
[TBL] [Abstract][Full Text] [Related]
16. Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL.
Murray JT; Campbell DG; Peggie M; Mora A; Cohen P
Biochem J; 2004 Dec; 384(Pt 3):489-94. PubMed ID: 15461588
[TBL] [Abstract][Full Text] [Related]
17. Evidence that 3-phosphoinositide-dependent protein kinase-1 mediates phosphorylation of p70 S6 kinase in vivo at Thr-412 as well as Thr-252.
Balendran A; Currie R; Armstrong CG; Avruch J; Alessi DR
J Biol Chem; 1999 Dec; 274(52):37400-6. PubMed ID: 10601311
[TBL] [Abstract][Full Text] [Related]
18. RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1.
Kim DW; Hwang JH; Suh JM; Kim H; Song JH; Hwang ES; Hwang IY; Park KC; Chung HK; Kim JM; Park J; Hemmings BA; Shong M
Mol Endocrinol; 2003 Jul; 17(7):1382-94. PubMed ID: 12738763
[TBL] [Abstract][Full Text] [Related]
19. Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1.
Wick MJ; Dong LQ; Riojas RA; Ramos FJ; Liu F
J Biol Chem; 2000 Dec; 275(51):40400-6. PubMed ID: 11006271
[TBL] [Abstract][Full Text] [Related]
20. Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change.
Milburn CC; Deak M; Kelly SM; Price NC; Alessi DR; Van Aalten DM
Biochem J; 2003 Nov; 375(Pt 3):531-8. PubMed ID: 12964941
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
