124 related articles for article (PubMed ID: 9096301)
1. Encoded combinatorial chemistry: synthesis and screening of a library of highly functionalized pyrrolidines.
Maclean D; Schullek JR; Murphy MM; Ni ZJ; Gordon EM; Gallop MA
Proc Natl Acad Sci U S A; 1997 Apr; 94(7):2805-10. PubMed ID: 9096301
[TBL] [Abstract][Full Text] [Related]
2. Versatile approach to encoding combinatorial organic syntheses using chemically robust secondary amine tags.
Ni ZJ; Maclean D; Holmes CP; Murphy MM; Ruhland B; Jacobs JW; Gordon EM; Gallop MA
J Med Chem; 1996 Apr; 39(8):1601-8. PubMed ID: 8648599
[TBL] [Abstract][Full Text] [Related]
3. An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening.
MacConnell AB; Price AK; Paegel BM
ACS Comb Sci; 2017 Mar; 19(3):181-192. PubMed ID: 28199790
[TBL] [Abstract][Full Text] [Related]
4. ACE inhibitors hypothesis generation for selective design, synthesis and biological evaluation of 3-mercapto-2-methyl-propanoyl-pyrrolidine-3-imine derivatives as antihypertensive agents.
Ismail MA; Nabil Aboul-Enein M; Abouzid KA; Abou El Ella DA; Ismail NS
Bioorg Med Chem; 2009 May; 17(10):3739-46. PubMed ID: 19403313
[TBL] [Abstract][Full Text] [Related]
5. Application of combinatorial library methods in cancer research and drug discovery.
Lam KS
Anticancer Drug Des; 1997 Apr; 12(3):145-67. PubMed ID: 9154108
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods.
Baumann M; Baxendale IR; Kuratli C; Ley SV; Martin RE; Schneider J
ACS Comb Sci; 2011 Jul; 13(4):405-13. PubMed ID: 21528880
[TBL] [Abstract][Full Text] [Related]
7. A method using angiotensin converting enzyme immobilized on magnetic beads for inhibitor screening.
Tang W; Jia B; Zhou J; Liu J; Wang J; Ma D; Li P; Chen J
J Pharm Biomed Anal; 2019 Feb; 164():223-230. PubMed ID: 30391811
[TBL] [Abstract][Full Text] [Related]
8. The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of aryloxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT₇ receptor antagonists.
Zajdel P; Kurczab R; Grychowska K; Satała G; Pawłowski M; Bojarski AJ
Eur J Med Chem; 2012 Oct; 56():348-60. PubMed ID: 22926225
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and enzyme inhibitory activities of new trifluoromethyl-containing inhibitors for angiotensin converting enzyme.
Ojima I; Jameison FA; Pete B; Radunz H; Schittenhelm C; Lindner HJ; Emith AE
Drug Des Discov; 1994 Feb; 11(2):91-113. PubMed ID: 8075303
[TBL] [Abstract][Full Text] [Related]
10. Mercaptoacyl dipeptides as orally active dual inhibitors of angiotensin-converting enzyme and neutral endopeptidase.
Fink CA; Carlson JE; McTaggart PA; Qiao Y; Webb R; Chatelain R; Jeng AY; Trapani AJ
J Med Chem; 1996 Aug; 39(16):3158-68. PubMed ID: 8759637
[TBL] [Abstract][Full Text] [Related]
11. Encoding method for OBOC small molecule libraries using a biphasic approach for ladder-synthesis of coding tags.
Wang X; Zhang J; Song A; Lebrilla CB; Lam KS
J Am Chem Soc; 2004 May; 126(18):5740-9. PubMed ID: 15125667
[TBL] [Abstract][Full Text] [Related]
12. Method for screening and MALDI-TOF MS sequencing of encoded combinatorial libraries.
Hu BH; Jones MR; Messersmith PB
Anal Chem; 2007 Oct; 79(19):7275-85. PubMed ID: 17713965
[TBL] [Abstract][Full Text] [Related]
13. DNA-Encoded Solid-Phase Synthesis: Encoding Language Design and Complex Oligomer Library Synthesis.
MacConnell AB; McEnaney PJ; Cavett VJ; Paegel BM
ACS Comb Sci; 2015 Sep; 17(9):518-34. PubMed ID: 26290177
[TBL] [Abstract][Full Text] [Related]
14. Synthesis of hydantoins and thiohydantoins spiro-fused to pyrrolidines: druglike molecules based on the 2-arylethyl amine scaffold.
Blanco-Ania D; Hermkens PH; Sliedregt LA; Scheeren HW; Rutjes FP
J Comb Chem; 2009; 11(4):527-38. PubMed ID: 19472985
[TBL] [Abstract][Full Text] [Related]
15. Effect of varying chain length between P(1) and P(1') position of tripeptidomimics on activity of angiotensin-converting enzyme inhibitors.
Chaudhary S; Vats ID; Chopra M; Biswas P; Pasha S
Bioorg Med Chem Lett; 2009 Aug; 19(15):4364-6. PubMed ID: 19523823
[TBL] [Abstract][Full Text] [Related]
16. Design of orally active dual inhibitors of neutral endopeptidase and angiotensin-converting enzyme with long duration of action.
Fournie-Zaluski MC; Coric P; Thery V; Gonzalez W; Meudal H; Turcaud S; Michel JB; Roques BP
J Med Chem; 1996 Jun; 39(13):2594-608. PubMed ID: 8691458
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and discovery of highly functionalized mono- and bis-spiro-pyrrolidines as potent cholinesterase enzyme inhibitors.
Kia Y; Osman H; Suresh Kumar R; Basiri A; Murugaiyah V
Bioorg Med Chem Lett; 2014 Apr; 24(7):1815-9. PubMed ID: 24594354
[TBL] [Abstract][Full Text] [Related]
18. Ionic liquid-enabled synthesis, cholinesterase inhibitory activity, and molecular docking study of highly functionalized tetrasubstituted pyrrolidines.
Kumar RS; Almansour AI; Arumugam N; Althomili DMQ; Altaf M; Basiri A; D K; Sai Manohar T; S V
Bioorg Chem; 2018 Apr; 77():263-268. PubMed ID: 29421701
[TBL] [Abstract][Full Text] [Related]
19. A novel and rapid encoding method based on mass spectrometry for "one-bead-one-compound" small molecule combinatorial libraries.
Song A; Zhang J; Lebrilla CB; Lam KS
J Am Chem Soc; 2003 May; 125(20):6180-8. PubMed ID: 12785850
[TBL] [Abstract][Full Text] [Related]
20. In silico design and synthesis of piperazine-1-pyrrolidine-2,5-dione scaffold-based novel malic enzyme inhibitors.
Zhang YJ; Wang Z; Sprous D; Nabioullin R
Bioorg Med Chem Lett; 2006 Feb; 16(3):525-8. PubMed ID: 16288866
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
