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6. Inhibition of the ATP-driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of age-related macular degeneration. Bergmann M; Schütt F; Holz FG; Kopitz J FASEB J; 2004 Mar; 18(3):562-4. PubMed ID: 14715704 [TBL] [Abstract][Full Text] [Related]
7. Inhibition of RPE lysosomal and antioxidant activity by the age pigment lipofuscin. Shamsi FA; Boulton M Invest Ophthalmol Vis Sci; 2001 Nov; 42(12):3041-6. PubMed ID: 11687553 [TBL] [Abstract][Full Text] [Related]
8. [Introduction of the lipofuscin-fluorophor A2E into the lysosomal compartment of human retinal pigment epithelial cells by coupling to LDL particles. An in vitro model of retinal pigment epithelium cell aging]. Holz FG; Schütt F; Kopitz J; Völcker HE Ophthalmologe; 1999 Dec; 96(12):781-5. PubMed ID: 10643311 [TBL] [Abstract][Full Text] [Related]
9. Isolation of intact lysosomes from human RPE cells and effects of A2-E on the integrity of the lysosomal and other cellular membranes. Schütt F; Bergmann M; Holz FG; Kopitz J Graefes Arch Clin Exp Ophthalmol; 2002 Dec; 240(12):983-8. PubMed ID: 12483320 [TBL] [Abstract][Full Text] [Related]
10. Aging of cultured retinal pigment epithelial cells: oxidative reactions, lipofuscin formation and blue light damage. Nilsson SE; Sundelin SP; Wihlmark U; Brunk UT Doc Ophthalmol; 2003 Jan; 106(1):13-6. PubMed ID: 12675480 [TBL] [Abstract][Full Text] [Related]
11. Formation of lipofuscin in cultured retinal pigment epithelial cells exposed to pre-oxidized photoreceptor outer segments. Wihlmark U; Wrigstad A; Roberg K; Brunk UT; Nilsson SE APMIS; 1996 Apr; 104(4):272-9. PubMed ID: 8645466 [TBL] [Abstract][Full Text] [Related]
12. Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage. Brandstetter C; Mohr LK; Latz E; Holz FG; Krohne TU J Mol Med (Berl); 2015 Aug; 93(8):905-16. PubMed ID: 25783493 [TBL] [Abstract][Full Text] [Related]
13. Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin. Holz FG; Schütt F; Kopitz J; Eldred GE; Kruse FE; Völcker HE; Cantz M Invest Ophthalmol Vis Sci; 1999 Mar; 40(3):737-43. PubMed ID: 10067978 [TBL] [Abstract][Full Text] [Related]
14. Autofluorescent inclusions in long-term postconfluent cultures of retinal pigment epithelium. Burke JM; Skumatz CM Invest Ophthalmol Vis Sci; 1998 Jul; 39(8):1478-86. PubMed ID: 9660497 [TBL] [Abstract][Full Text] [Related]
15. Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells. Davies S; Elliott MH; Floor E; Truscott TG; Zareba M; Sarna T; Shamsi FA; Boulton ME Free Radic Biol Med; 2001 Jul; 31(2):256-65. PubMed ID: 11440838 [TBL] [Abstract][Full Text] [Related]
16. Spectral profiling of autofluorescence associated with lipofuscin, Bruch's Membrane, and sub-RPE deposits in normal and AMD eyes. Marmorstein AD; Marmorstein LY; Sakaguchi H; Hollyfield JG Invest Ophthalmol Vis Sci; 2002 Jul; 43(7):2435-41. PubMed ID: 12091448 [TBL] [Abstract][Full Text] [Related]
17. [Mechanism of the inhibition of lysosomal functions in the retinal pigment epithelium by lipofuscin retinoid component A2-E]. Schütt F; Bergmann M; Kopitz J; Holz FG Ophthalmologe; 2001 Aug; 98(8):721-4. PubMed ID: 11552410 [TBL] [Abstract][Full Text] [Related]
18. The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells. Vives-Bauza C; Anand M; Shiraz AK; Magrane J; Gao J; Vollmer-Snarr HR; Manfredi G; Finnemann SC J Biol Chem; 2008 Sep; 283(36):24770-80. PubMed ID: 18621729 [TBL] [Abstract][Full Text] [Related]
19. [A retinoid constituent of lipofuscin, A2-E, is a photosensitizer in human retinal pigment epithelial cells]. Schütt F; Davies S; Kopitz J; Boulton M; Holz FG Ophthalmologe; 2000 Oct; 97(10):682-7. PubMed ID: 11105544 [TBL] [Abstract][Full Text] [Related]
20. Experimental light damage increases lipofuscin in the retinal pigment epithelium of Japanese quail (Coturnix coturnix japonica). Fite KV; Bengston L; Donaghey B Exp Eye Res; 1993 Oct; 57(4):449-60. PubMed ID: 8282031 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]