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3. NMR studies of the secondary structure in solution and the steroid binding site of delta5-3-ketosteroid isomerase in complexes with diamagnetic and paramagnetic steroids. Zhao Q; Abeygunawardana C; Mildvan AS Biochemistry; 1997 Mar; 36(12):3458-72. PubMed ID: 9131995 [TBL] [Abstract][Full Text] [Related]
4. Solution structure of Delta 5-3-ketosteroid isomerase complexed with the steroid 19-nortestosterone hemisuccinate. Massiah MA; Abeygunawardana C; Gittis AG; Mildvan AS Biochemistry; 1998 Oct; 37(42):14701-12. PubMed ID: 9778345 [TBL] [Abstract][Full Text] [Related]
5. Structure and enzymology of Delta5-3-ketosteroid isomerase. Ha NC; Choi G; Choi KY; Oh BH Curr Opin Struct Biol; 2001 Dec; 11(6):674-8. PubMed ID: 11751047 [TBL] [Abstract][Full Text] [Related]
6. Contribution of the hydrogen-bond network involving a tyrosine triad in the active site to the structure and function of a highly proficient ketosteroid isomerase from Pseudomonas putida biotype B. Kim DH; Jang DS; Nam GH; Choi G; Kim JS; Ha NC; Kim MS; Oh BH; Choi KY Biochemistry; 2000 Apr; 39(16):4581-9. PubMed ID: 10769113 [TBL] [Abstract][Full Text] [Related]
7. Hydrogen bonding at the active site of delta 5-3-ketosteroid isomerase. Zhao Q; Abeygunawardana C; Gittis AG; Mildvan AS Biochemistry; 1997 Dec; 36(48):14616-26. PubMed ID: 9398180 [TBL] [Abstract][Full Text] [Related]
8. High-resolution crystal structures of delta5-3-ketosteroid isomerase with and without a reaction intermediate analogue. Kim SW; Cha SS; Cho HS; Kim JS; Ha NC; Cho MJ; Joo S; Kim KK; Choi KY; Oh BH Biochemistry; 1997 Nov; 36(46):14030-6. PubMed ID: 9369474 [TBL] [Abstract][Full Text] [Related]
9. The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni. Nam GH; Cha SS; Yun YS; Oh YH; Hong BH; Lee HS; Choi KY Biochem J; 2003 Oct; 375(Pt 2):297-305. PubMed ID: 12852789 [TBL] [Abstract][Full Text] [Related]
10. Crystal structure and enzyme mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni. Cho HS; Choi G; Choi KY; Oh BH Biochemistry; 1998 Jun; 37(23):8325-30. PubMed ID: 9622484 [TBL] [Abstract][Full Text] [Related]
11. QM/MM modelling of ketosteroid isomerase reactivity indicates that active site closure is integral to catalysis. van der Kamp MW; Chaudret R; Mulholland AJ FEBS J; 2013 Jul; 280(13):3120-31. PubMed ID: 23356661 [TBL] [Abstract][Full Text] [Related]
12. Ground state destabilization from a positioned general base in the ketosteroid isomerase active site. Ruben EA; Schwans JP; Sonnett M; Natarajan A; Gonzalez A; Tsai Y; Herschlag D Biochemistry; 2013 Feb; 52(6):1074-81. PubMed ID: 23311398 [TBL] [Abstract][Full Text] [Related]
13. Kinetic and ultraviolet spectroscopic studies of active-site mutants of delta 5-3-ketosteroid isomerase. Kuliopulos A; Mildvan AS; Shortle D; Talalay P Biochemistry; 1989 Jan; 28(1):149-59. PubMed ID: 2706241 [TBL] [Abstract][Full Text] [Related]
14. Maintenance of alpha-helical structures by phenyl rings in the active-site tyrosine triad contributes to catalysis and stability of ketosteroid isomerase from Pseudomonas putida biotype B. Nam GH; Jang DS; Cha SS; Lee TH; Kim DH; Hong BH; Yun YS; Oh BH; Choi KY Biochemistry; 2001 Nov; 40(45):13529-37. PubMed ID: 11695900 [TBL] [Abstract][Full Text] [Related]
15. Contribution of a low-barrier hydrogen bond to catalysis is not significant in ketosteroid isomerase. Jang DS; Choi G; Cha HJ; Shin S; Hong BH; Lee HJ; Lee HC; Choi KY Mol Cells; 2015 May; 38(5):409-15. PubMed ID: 25947291 [TBL] [Abstract][Full Text] [Related]
16. Hybrid quantum/classical molecular dynamics simulations of the proton transfer reactions catalyzed by ketosteroid isomerase: analysis of hydrogen bonding, conformational motions, and electrostatics. Chakravorty DK; Soudackov AV; Hammes-Schiffer S Biochemistry; 2009 Nov; 48(44):10608-19. PubMed ID: 19799395 [TBL] [Abstract][Full Text] [Related]
17. Computational study of ketosteroid isomerase: insights from molecular dynamics simulation of enzyme bound substrate and intermediate. Mazumder D; Kahn K; Bruice TC J Am Chem Soc; 2003 Jun; 125(25):7553-61. PubMed ID: 12812495 [TBL] [Abstract][Full Text] [Related]
18. Role of conserved Met112 residue in the catalytic activity and stability of ketosteroid isomerase. Cha HJ; Jang do S; Jeong JH; Hong BH; Yun YS; Shin EJ; Choi KY Biochim Biophys Acta; 2016 Oct; 1864(10):1322-7. PubMed ID: 27375051 [TBL] [Abstract][Full Text] [Related]
19. Identification of active site residues by site-directed mutagenesis of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B. Kim SW; Choi KY J Bacteriol; 1995 May; 177(9):2602-5. PubMed ID: 7730300 [TBL] [Abstract][Full Text] [Related]
20. Substrate polarization by residues in delta 5-3-ketosteroid isomerase probed by site-directed mutagenesis and UV resonance Raman spectroscopy. Austin JC; Kuliopulos A; Mildvan AS; Spiro TG Protein Sci; 1992 Feb; 1(2):259-70. PubMed ID: 1339027 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]