88 related articles for article (PubMed ID: 9106626)
1. 2-Chloro-2'-deoxyadenosine, an antileukemic drug, has an early effect on cellular mitochondrial function.
Hentosh P; Tibudan M
Mol Pharmacol; 1997 Apr; 51(4):613-9. PubMed ID: 9106626
[TBL] [Abstract][Full Text] [Related]
2. Analysis of 2-chloro-2'-deoxyadenosine incorporation into cellular DNA by quantitative polymerase chain reaction.
Yuh SH; Tibudan M; Hentosh P
Anal Biochem; 1998 Aug; 262(1):1-8. PubMed ID: 9735141
[TBL] [Abstract][Full Text] [Related]
3. Effects of cytotoxicity of 2-chloro-2'-deoxyadenosine and 2-bromo-2'-deoxyadenosine on cell growth, clonogenicity, DNA synthesis, and cell cycle kinetics.
Huang MC; Ashmun RA; Avery TL; Kuehl M; Blakley RL
Cancer Res; 1986 May; 46(5):2362-8. PubMed ID: 2421877
[TBL] [Abstract][Full Text] [Related]
4. Nucleotide excision repair-deficient human cells in culture exhibit decreased survival after 2-chlorodeoxyadenosine treatment.
Lawrenzi J; Bunnell A; Hentosh P
Anticancer Res; 2003; 23(4):3141-5. PubMed ID: 12926046
[TBL] [Abstract][Full Text] [Related]
5. Biochemical pharmacology of 2-chlorodeoxyadenosine in malignant human hematopoietic cell lines and therapeutic effects of 2-bromodeoxyadenosine in drug combinations in mice.
Avery TL; Rehg JE; Lumm WC; Harwood FC; Santana VM; Blakley RL
Cancer Res; 1989 Sep; 49(18):4972-8. PubMed ID: 2569929
[TBL] [Abstract][Full Text] [Related]
6. 2-Chloro-2'-deoxyadenosine-induced apoptosis in T leukemia cells is mediated via a caspase-3-dependent mitochondrial feedback amplification loop.
Conrad DM; Robichaud MR; Mader JS; Boudreau RT; Richardson AM; Giacomantonio CA; Hoskin DW
Int J Oncol; 2008 Jun; 32(6):1325-33. PubMed ID: 18497995
[TBL] [Abstract][Full Text] [Related]
7. Increased lactate production follows loss of mitochondrial membrane potential during apoptosis of human leukaemia cells.
Tiefenthaler M; Amberger A; Bacher N; Hartmann BL; Margreiter R; Kofler R; Konwalinka G
Br J Haematol; 2001 Sep; 114(3):574-80. PubMed ID: 11552982
[TBL] [Abstract][Full Text] [Related]
8. Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria.
Genini D; Adachi S; Chao Q; Rose DW; Carrera CJ; Cottam HB; Carson DA; Leoni LM
Blood; 2000 Nov; 96(10):3537-43. PubMed ID: 11071652
[TBL] [Abstract][Full Text] [Related]
9. Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy.
Carrera CJ; Terai C; Lotz M; Curd JG; Piro LD; Beutler E; Carson DA
J Clin Invest; 1990 Nov; 86(5):1480-8. PubMed ID: 1700795
[TBL] [Abstract][Full Text] [Related]
10. Biochemical pharmacology and resistance to 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, a novel analogue of cladribine in human leukemic cells.
Lotfi K; MÃ¥nsson E; Spasokoukotskaja T; Pettersson B; Liliemark J; Peterson C; Eriksson S; Albertioni F
Clin Cancer Res; 1999 Sep; 5(9):2438-44. PubMed ID: 10499616
[TBL] [Abstract][Full Text] [Related]
11. Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine.
Robertson LE; Chubb S; Meyn RE; Story M; Ford R; Hittelman WN; Plunkett W
Blood; 1993 Jan; 81(1):143-50. PubMed ID: 8093345
[TBL] [Abstract][Full Text] [Related]
12. 2-Chloro-2'-deoxyadenosine (2CdA) biochemical aspects of antileukemic efficacy.
Fabianowska-Majewska K; Wyczechowska D
Acta Pol Pharm; 1996; 53(4):231-9. PubMed ID: 9415193
[TBL] [Abstract][Full Text] [Related]
13. The antileukemia drug 2-chloro-2'-deoxyadenosine: an intrinsic transcriptional antagonist.
Hartman WR; Hentosh P
Mol Pharmacol; 2004 Jan; 65(1):227-34. PubMed ID: 14722255
[TBL] [Abstract][Full Text] [Related]
14. In vitro transcription of DNA containing 2-chloro-2'-deoxyadenosine monophosphate.
Hentosh P; Tibudan M
Mol Pharmacol; 1995 Nov; 48(5):897-904. PubMed ID: 7476921
[TBL] [Abstract][Full Text] [Related]
15. Effect of anti-HIV 2'-beta-fluoro-2',3'-dideoxynucleoside analogs on the cellular content of mitochondrial DNA and on lactate production.
Tsai CH; Doong SL; Johns DG; Driscoll JS; Cheng YC
Biochem Pharmacol; 1994 Oct; 48(7):1477-81. PubMed ID: 7945448
[TBL] [Abstract][Full Text] [Related]
16. Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2',3'-dideoxycytidine.
Chen CH; Cheng YC
J Biol Chem; 1989 Jul; 264(20):11934-7. PubMed ID: 2745424
[TBL] [Abstract][Full Text] [Related]
17. Mechanisms of inhibition of DNA synthesis by 2-chlorodeoxyadenosine in human lymphoblastic cells.
Griffig J; Koob R; Blakley RL
Cancer Res; 1989 Dec; 49(24 Pt 1):6923-8. PubMed ID: 2573423
[TBL] [Abstract][Full Text] [Related]
18. Resistance to 2-chloro-2'-deoxyadenosine of the human B-cell leukemia cell line EHEB.
Cardoen S; Van Den Neste E; Smal C; Rosier JF; Delacauw A; Ferrant A; Van den Berghe G; Bontemps F
Clin Cancer Res; 2001 Nov; 7(11):3559-66. PubMed ID: 11705877
[TBL] [Abstract][Full Text] [Related]
19. Sublethal concentrations of gemcitabine (2',2'-difluorodeoxycytidine) alter mitochondrial ultrastructure and function without reducing mitochondrial DNA content in BxPC-3 human pancreatic carcinoma cells.
Yeo TK; Kintner J; Armand R; Perez R; Lewis LD
Hum Exp Toxicol; 2007 Dec; 26(12):911-21. PubMed ID: 18375634
[TBL] [Abstract][Full Text] [Related]
20. 4-Quinolones cause a selective loss of mitochondrial DNA from mouse L1210 leukemia cells.
Lawrence JW; Darkin-Rattray S; Xie F; Neims AH; Rowe TC
J Cell Biochem; 1993 Feb; 51(2):165-74. PubMed ID: 8440750
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]