BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

427 related articles for article (PubMed ID: 9108484)

  • 1. MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption.
    Drewes G; Ebneth A; Preuss U; Mandelkow EM; Mandelkow E
    Cell; 1997 Apr; 89(2):297-308. PubMed ID: 9108484
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes.
    Trinczek B; Brajenovic M; Ebneth A; Drewes G
    J Biol Chem; 2004 Feb; 279(7):5915-23. PubMed ID: 14594945
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells.
    Ebneth A; Drewes G; Mandelkow EM; Mandelkow E
    Cell Motil Cytoskeleton; 1999 Nov; 44(3):209-24. PubMed ID: 10542369
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation of tau is regulated by PKN.
    Taniguchi T; Kawamata T; Mukai H; Hasegawa H; Isagawa T; Yasuda M; Hashimoto T; Terashima A; Nakai M; Mori H; Ono Y; Tanaka C
    J Biol Chem; 2001 Mar; 276(13):10025-31. PubMed ID: 11104762
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262.
    Drewes G; Trinczek B; Illenberger S; Biernat J; Schmitt-Ulms G; Meyer HE; Mandelkow EM; Mandelkow E
    J Biol Chem; 1995 Mar; 270(13):7679-88. PubMed ID: 7706316
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1.
    Timm T; Li XY; Biernat J; Jiao J; Mandelkow E; Vandekerckhove J; Mandelkow EM
    EMBO J; 2003 Oct; 22(19):5090-101. PubMed ID: 14517247
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules.
    Trinczek B; Biernat J; Baumann K; Mandelkow EM; Mandelkow E
    Mol Biol Cell; 1995 Dec; 6(12):1887-902. PubMed ID: 8590813
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of Tau and MAP2 as novel substrates of Rho-kinase and myosin phosphatase.
    Amano M; Kaneko T; Maeda A; Nakayama M; Ito M; Yamauchi T; Goto H; Fukata Y; Oshiro N; Shinohara A; Iwamatsu A; Kaibuchi K
    J Neurochem; 2003 Nov; 87(3):780-90. PubMed ID: 14535960
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glycogen synthase kinase (GSK) 3beta directly phosphorylates Serine 212 in the regulatory loop and inhibits microtubule affinity-regulating kinase (MARK) 2.
    Timm T; Balusamy K; Li X; Biernat J; Mandelkow E; Mandelkow EM
    J Biol Chem; 2008 Jul; 283(27):18873-82. PubMed ID: 18424437
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity.
    Biernat J; Wu YZ; Timm T; Zheng-Fischhöfer Q; Mandelkow E; Meijer L; Mandelkow EM
    Mol Biol Cell; 2002 Nov; 13(11):4013-28. PubMed ID: 12429843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics.
    Illenberger S; Drewes G; Trinczek B; Biernat J; Meyer HE; Olmsted JB; Mandelkow EM; Mandelkow E
    J Biol Chem; 1996 May; 271(18):10834-43. PubMed ID: 8631898
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Signaling from MARK to tau: regulation, cytoskeletal crosstalk, and pathological phosphorylation.
    Timm T; Matenia D; Li XY; Griesshaber B; Mandelkow EM
    Neurodegener Dis; 2006; 3(4-5):207-17. PubMed ID: 17047359
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons.
    Mandelkow EM; Thies E; Trinczek B; Biernat J; Mandelkow E
    J Cell Biol; 2004 Oct; 167(1):99-110. PubMed ID: 15466480
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Spred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeleton.
    Johne C; Matenia D; Li XY; Timm T; Balusamy K; Mandelkow EM
    Mol Biol Cell; 2008 Apr; 19(4):1391-403. PubMed ID: 18216281
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interactions of MAP/microtubule affinity regulating kinases with the adaptor complex AP-2 of clathrin-coated vesicles.
    Schmitt-Ulms G; Matenia D; Drewes G; Mandelkow EM
    Cell Motil Cytoskeleton; 2009 Aug; 66(8):661-72. PubMed ID: 19536824
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans.
    Goedert M; Baur CP; Ahringer J; Jakes R; Hasegawa M; Spillantini MG; Smith MJ; Hill F
    J Cell Sci; 1996 Nov; 109 ( Pt 11)():2661-72. PubMed ID: 8937984
    [TBL] [Abstract][Full Text] [Related]  

  • 17. cDNA cloning and characterization of rat Clk3, a LAMMER kinase predominately expressed in testis.
    Becker W; Kentrup H; Heukelbach J; Joost HG
    Biochim Biophys Acta; 1996 Jun; 1312(1):63-7. PubMed ID: 8679717
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments.
    Schneider A; Biernat J; von Bergen M; Mandelkow E; Mandelkow EM
    Biochemistry; 1999 Mar; 38(12):3549-58. PubMed ID: 10090741
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The KLDpT activation loop motif is critical for MARK kinase activity.
    Sonntag T; Moresco JJ; Yates JR; Montminy M
    PLoS One; 2019; 14(12):e0225727. PubMed ID: 31794565
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Microtubule/MAP-affinity regulating kinase (MARK) is activated by phenylarsine oxide in situ and phosphorylates tau within its microtubule-binding domain.
    Jenkins SM; Johnson GV
    J Neurochem; 2000 Apr; 74(4):1463-8. PubMed ID: 10737602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.