BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 9111224)

  • 1. Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes.
    Hammons GJ; Milton D; Stepps K; Guengerich FP; Tukey RH; Kadlubar FF
    Carcinogenesis; 1997 Apr; 18(4):851-4. PubMed ID: 9111224
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
    Turesky RJ; Lang NP; Butler MA; Teitel CH; Kadlubar FF
    Carcinogenesis; 1991 Oct; 12(10):1839-45. PubMed ID: 1934265
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
    Turesky RJ; Constable A; Richoz J; Varga N; Markovic J; Martin MV; Guengerich FP
    Chem Res Toxicol; 1998 Aug; 11(8):925-36. PubMed ID: 9705755
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regioselective differences in C(8)- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by human and rat liver microsomes and cytochromes P450 1A2.
    Turesky RJ; Parisod V; Huynh-Ba T; Langouët S; Guengerich FP
    Chem Res Toxicol; 2001 Jul; 14(7):901-11. PubMed ID: 11453738
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.
    Gu D; McNaughton L; Lemaster D; Lake BG; Gooderham NJ; Kadlubar FF; Turesky RJ
    Chem Res Toxicol; 2010 Apr; 23(4):788-801. PubMed ID: 20192249
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes.
    Koehl W; Amin S; Staretz ME; Ueng YF; Yamazaki H; Tateishi T; Guengerich FP; Hecht SS
    Cancer Res; 1996 Jan; 56(2):316-24. PubMed ID: 8542586
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Caffeine Cytochrome P450 1A2 Metabolic Phenotype Does Not Predict the Metabolism of Heterocyclic Aromatic Amines in Humans.
    Turesky RJ; White KK; Wilkens LR; Le Marchand L
    Chem Res Toxicol; 2015 Aug; 28(8):1603-15. PubMed ID: 26203673
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
    Patten CJ; Smith TJ; Murphy SE; Wang MH; Lee J; Tynes RE; Koch P; Yang CS
    Arch Biochem Biophys; 1996 Sep; 333(1):127-38. PubMed ID: 8806763
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanisms of cytochrome P450 1A2-mediated formation of N-hydroxy arylamines and heterocyclic amines and their reaction with guanyl residues.
    Guengerich FP; Humphreys WG; Yun CH; Hammons GJ; Kadlubar FF; Seto Y; Okazaki O; Martin MV
    Princess Takamatsu Symp; 1995; 23():78-84. PubMed ID: 8844798
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
    Shimada T; Hayes CL; Yamazaki H; Amin S; Hecht SS; Guengerich FP; Sutter TR
    Cancer Res; 1996 Jul; 56(13):2979-84. PubMed ID: 8674051
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
    Sadrieh N; Snyderwine EG
    Carcinogenesis; 1995 Jul; 16(7):1549-55. PubMed ID: 7614688
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recombinant human P450 forms 1A1, 1A2, and 1B1 catalyze the bioactivation of heterocyclic amine mutagens in Escherichia coli lacZ strains.
    Josephy PD; Batty SM; Boverhof DR
    Environ Mol Mutagen; 2001; 38(1):12-8. PubMed ID: 11473383
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.
    Oda Y; Aryal P; Terashita T; Gillam EM; Guengerich FP; Shimada T
    Mutat Res; 2001 May; 492(1-2):81-90. PubMed ID: 11377247
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxification pathway catalyzed by cytochrome P450 1A2.
    Langouët S; Welti DH; Kerriguy N; Fay LB; Huynh-Ba T; Markovic J; Guengerich FP; Guillouzo A; Turesky RJ
    Chem Res Toxicol; 2001 Feb; 14(2):211-21. PubMed ID: 11258970
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1.
    Crofts FG; Sutter TR; Strickland PT
    Carcinogenesis; 1998 Nov; 19(11):1969-73. PubMed ID: 9855011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytochrome P450-mediated metabolism and DNA binding of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline and its carcinogenic isomer 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in mice.
    Turesky RJ; Bessette EE; Dunbar D; Liberman RG; Skipper PL
    Chem Res Toxicol; 2012 Feb; 25(2):410-21. PubMed ID: 22118226
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolic activation of N-hydroxy arylamines and N-hydroxy heterocyclic amines by human sulfotransferase(s).
    Chou HC; Lang NP; Kadlubar FF
    Cancer Res; 1995 Feb; 55(3):525-9. PubMed ID: 7834621
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay.
    Aryal P; Terashita T; Guengerich FP; Shimada T; Oda Y
    Environ Mol Mutagen; 2000; 36(2):121-6. PubMed ID: 11013410
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.
    McManus ME; Burgess WM; Veronese ME; Huggett A; Quattrochi LC; Tukey RH
    Cancer Res; 1990 Jun; 50(11):3367-76. PubMed ID: 2334931
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.