These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
296 related articles for article (PubMed ID: 9113345)
1. Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1. Schmider J; Greenblatt DJ; Fogelman SM; von Moltke LL; Shader RI Biopharm Drug Dispos; 1997 Apr; 18(3):227-40. PubMed ID: 9113345 [TBL] [Abstract][Full Text] [Related]
2. Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A. von Moltke LL; Greenblatt DJ; Grassi JM; Granda BW; Venkatakrishnan K; Schmider J; Harmatz JS; Shader RI J Pharm Pharmacol; 1998 Sep; 50(9):997-1004. PubMed ID: 9811160 [TBL] [Abstract][Full Text] [Related]
3. Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities? Yu A; Haining RL Drug Metab Dispos; 2001 Nov; 29(11):1514-20. PubMed ID: 11602530 [TBL] [Abstract][Full Text] [Related]
4. Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily. Gorski JC; Jones DR; Wrighton SA; Hall SD Biochem Pharmacol; 1994 Jul; 48(1):173-82. PubMed ID: 8043020 [TBL] [Abstract][Full Text] [Related]
5. The role of CYP2D6 in primary and secondary oxidative metabolism of dextromethorphan: in vitro studies using human liver microsomes. Kerry NL; Somogyi AA; Bochner F; Mikus G Br J Clin Pharmacol; 1994 Sep; 38(3):243-8. PubMed ID: 7826826 [TBL] [Abstract][Full Text] [Related]
6. Inhibition of cytochrome P450 by nefazodone in vitro: studies of dextromethorphan O- and N-demethylation. Schmider J; Greenblatt DJ; von Moltke LL; Harmatz JS; Shader RI Br J Clin Pharmacol; 1996 Apr; 41(4):339-43. PubMed ID: 8730981 [TBL] [Abstract][Full Text] [Related]
7. CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans. Jacqz-Aigrain E; Funck-Brentano C; Cresteil T Pharmacogenetics; 1993 Aug; 3(4):197-204. PubMed ID: 8220439 [TBL] [Abstract][Full Text] [Related]
8. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man. Venkatakrishnan K; von Moltke LL; Duan SX; Fleishaker JC; Shader RI; Greenblatt DJ J Pharm Pharmacol; 1998 Mar; 50(3):265-74. PubMed ID: 9600717 [TBL] [Abstract][Full Text] [Related]
9. Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes. Di Marco A; Yao D; Laufer R Eur J Biochem; 2003 Sep; 270(18):3768-77. PubMed ID: 12950260 [TBL] [Abstract][Full Text] [Related]
10. The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6. Madeira M; Levine M; Chang TK; Mirfazaelian A; Bellward GD Drug Metab Dispos; 2004 Apr; 32(4):460-7. PubMed ID: 16680870 [TBL] [Abstract][Full Text] [Related]
11. Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation. Jones DR; Gorski JC; Haehner BD; O'Mara EM; Hall SD Clin Pharmacol Ther; 1996 Oct; 60(4):374-84. PubMed ID: 8873685 [TBL] [Abstract][Full Text] [Related]
12. Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2. Yoshimoto K; Echizen H; Chiba K; Tani M; Ishizaki T Br J Clin Pharmacol; 1995 Apr; 39(4):421-31. PubMed ID: 7640150 [TBL] [Abstract][Full Text] [Related]
13. Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes. Transon C; Lecoeur S; Leemann T; Beaune P; Dayer P Eur J Clin Pharmacol; 1996; 51(1):79-85. PubMed ID: 8880056 [TBL] [Abstract][Full Text] [Related]
14. Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid. Taguchi K; Konishi T; Nishikawa H; Kitamura S Xenobiotica; 1999 Sep; 29(9):899-907. PubMed ID: 10548450 [TBL] [Abstract][Full Text] [Related]
15. Characterization of six in vitro reactions mediated by human cytochrome P450: application to the testing of cytochrome P450-directed antibodies. Schmider J; Greenblatt DJ; von Moltke LL; Harmatz JS; Duan SX; Karsov D; Shader RI Pharmacology; 1996 Feb; 52(2):125-34. PubMed ID: 8851634 [TBL] [Abstract][Full Text] [Related]
16. CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam. Hesse LM; Venkatakrishnan K; von Moltke LL; Shader RI; Greenblatt DJ Drug Metab Dispos; 2001 Feb; 29(2):133-40. PubMed ID: 11159802 [TBL] [Abstract][Full Text] [Related]
17. Enzyme kinetic modelling as a tool to analyse the behaviour of cytochrome P450 catalysed reactions: application to amitriptyline N-demethylation. Schmider J; Greenblatt DJ; Harmatz JS; Shader RI Br J Clin Pharmacol; 1996 Jun; 41(6):593-604. PubMed ID: 8799527 [TBL] [Abstract][Full Text] [Related]
18. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes. Lalovic B; Phillips B; Risler LL; Howald W; Shen DD Drug Metab Dispos; 2004 Apr; 32(4):447-54. PubMed ID: 15039299 [TBL] [Abstract][Full Text] [Related]
19. Primary and secondary oxidative metabolism of dextromethorphan. In vitro studies with female Sprague-Dawley and Dark Agouti rat liver microsomes. Kerry NL; Somogyi AA; Mikus G; Bochner F Biochem Pharmacol; 1993 Feb; 45(4):833-9. PubMed ID: 8452558 [TBL] [Abstract][Full Text] [Related]
20. Metabolism of dexfenfluramine in human liver microsomes and by recombinant enzymes: role of CYP2D6 and 1A2. Haritos VS; Ching MS; Ghabrial H; Gross AS; Taavitsainen P; Pelkonen O; Battaglia SE; Smallwood RA; Ahokas JT Pharmacogenetics; 1998 Oct; 8(5):423-32. PubMed ID: 9825834 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]