161 related articles for article (PubMed ID: 9115247)
1. Scanning alanine mutagenesis and de-peptidization of a Candida albicans myristoyl-CoA:protein N-myristoyltransferase octapeptide substrate reveals three elements critical for molecular recognition.
McWherter CA; Rocque WJ; Zupec ME; Freeman SK; Brown DL; Devadas B; Getman DP; Sikorski JA; Gordon JI
J Biol Chem; 1997 May; 272(18):11874-80. PubMed ID: 9115247
[TBL] [Abstract][Full Text] [Related]
2. Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: protein N-myristoyltransferase: a new approach to antifungal therapy.
Sikorski JA; Devadas B; Zupec ME; Freeman SK; Brown DL; Lu HF; Nagarajan S; Mehta PP; Wade AC; Kishore NS; Bryant ML; Getman DP; McWherter CA; Gordon JI
Biopolymers; 1997; 43(1):43-71. PubMed ID: 9174411
[TBL] [Abstract][Full Text] [Related]
3. Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.
Devadas B; Freeman SK; Zupec ME; Lu HF; Nagarajan SR; Kishore NS; Lodge JK; Kuneman DW; McWherter CA; Vinjamoori DV; Getman DP; Gordon JI; Sikorski JA
J Med Chem; 1997 Aug; 40(16):2609-25. PubMed ID: 9258368
[TBL] [Abstract][Full Text] [Related]
4. Conformationally constrained [p-(omega-aminoalkyl)phenacetyl]-L-seryl-L-lysyl dipeptide amides as potent peptidomimetic inhibitors of Candida albicans and human myristoyl-CoA:protein N-myristoyl transferase.
Nagarajan SR; Devadas B; Zupec ME; Freeman SK; Brown DL; Lu HF; Mehta PP; Kishore NS; McWherter CA; Getman DP; Gordon JI; Sikorski JA
J Med Chem; 1997 May; 40(10):1422-38. PubMed ID: 9154965
[TBL] [Abstract][Full Text] [Related]
5. Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent.
Lodge JK; Jackson-Machelski E; Higgins M; McWherter CA; Sikorski JA; Devadas B; Gordon JI
J Biol Chem; 1998 May; 273(20):12482-91. PubMed ID: 9575206
[TBL] [Abstract][Full Text] [Related]
6. Biochemical studies of Saccharomyces cerevisiae myristoyl-coenzyme A:protein N-myristoyltransferase mutants.
Zhang L; Jackson-Machelski E; Gordon JI
J Biol Chem; 1996 Dec; 271(51):33131-40. PubMed ID: 8955162
[TBL] [Abstract][Full Text] [Related]
7. N-myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA: protein N-myristoyltransferase.
Lodge JK; Jackson-Machelski E; Devadas B; Zupec ME; Getman DP; Kishore N; Freeman SK; McWherter CA; Sikorski JA; Gordon JI
Microbiology (Reading); 1997 Feb; 143 ( Pt 2)():357-366. PubMed ID: 9043113
[TBL] [Abstract][Full Text] [Related]
8. The substrate specificity of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase. Analysis of myristic acid analogs containing oxygen, sulfur, double bonds, triple bonds, and/or an aromatic residue.
Kishore NS; Lu TB; Knoll LJ; Katoh A; Rudnick DA; Mehta PP; Devadas B; Huhn M; Atwood JL; Adams SP
J Biol Chem; 1991 May; 266(14):8835-55. PubMed ID: 2026598
[TBL] [Abstract][Full Text] [Related]
9. Use of photoactivatable peptide substrates of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p) to characterize a myristoyl-CoA-Nmt1p-peptide ternary complex and to provide evidence for an ordered reaction mechanism.
Rudnick DA; Rocque WJ; McWherter CA; Toth MV; Jackson-Machelski E; Gordon JI
Proc Natl Acad Sci U S A; 1993 Feb; 90(3):1087-91. PubMed ID: 8430078
[TBL] [Abstract][Full Text] [Related]
10. Crystal structures of Candida albicans N-myristoyltransferase with two distinct inhibitors.
Sogabe S; Masubuchi M; Sakata K; Fukami TA; Morikami K; Shiratori Y; Ebiike H; Kawasaki K; Aoki Y; Shimma N; D'Arcy A; Winkler FK; Banner DW; Ohtsuka T
Chem Biol; 2002 Oct; 9(10):1119-28. PubMed ID: 12401496
[TBL] [Abstract][Full Text] [Related]
11. Molecular cloning and biochemical characterization of bovine spleen myristoyl CoA:protein N-myristoyltransferase.
Raju RV; Anderson JW; Datla RS; Sharma RK
Arch Biochem Biophys; 1997 Dec; 348(1):134-42. PubMed ID: 9390183
[TBL] [Abstract][Full Text] [Related]
12. Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans.
Lodge JK; Johnson RL; Weinberg RA; Gordon JI
J Biol Chem; 1994 Jan; 269(4):2996-3009. PubMed ID: 8300631
[TBL] [Abstract][Full Text] [Related]
13. Studies of the catalytic activities and substrate specificities of Saccharomyces cerevisiae myristoyl-coenzyme A: protein N-myristoyltransferase deletion mutants and human/yeast Nmt chimeras in Escherichia coli and S. cerevisiae.
Rudnick DA; Johnson RL; Gordon JI
J Biol Chem; 1992 Nov; 267(33):23852-61. PubMed ID: 1429724
[TBL] [Abstract][Full Text] [Related]
14. The substrate specificity of Saccharomyces cerevisiae myristoyl-CoA: protein N-myristoyltransferase. Polar probes of the enzyme's myristoyl-CoA recognition site.
Lu T; Li Q; Katoh A; Hernandez J; Duffin K; Jackson-Machelski E; Knoll LJ; Gokel GW; Gordon JI
J Biol Chem; 1994 Feb; 269(7):5346-57. PubMed ID: 8106519
[TBL] [Abstract][Full Text] [Related]
15. Myristoyl CoA:protein N-myristoyltransferase activities from rat liver and yeast possess overlapping yet distinct peptide substrate specificities.
Towler DA; Adams SP; Eubanks SR; Towery DS; Jackson-Machelski E; Glaser L; Gordon JI
J Biol Chem; 1988 Feb; 263(4):1784-90. PubMed ID: 3123478
[TBL] [Abstract][Full Text] [Related]
16. A comparative analysis of the kinetic mechanism and peptide substrate specificity of human and Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase.
Rocque WJ; McWherter CA; Wood DC; Gordon JI
J Biol Chem; 1993 May; 268(14):9964-71. PubMed ID: 8486723
[TBL] [Abstract][Full Text] [Related]
17. Design and syntheses of potent and selective dipeptide inhibitors of Candida albicans myristoyl-CoA:protein N-myristoyltransferase.
Devadas B; Zupec ME; Freeman SK; Brown DL; Nagarajan S; Sikorski JA; McWherter CA; Getman DP; Gordon JI
J Med Chem; 1995 May; 38(11):1837-40. PubMed ID: 7783114
[No Abstract] [Full Text] [Related]
18. Synthesis of myristoyl CoA analogues and myristoyl peptides as inhibitors of myristoyl CoA:protein N-myristoyltransferase.
Zheng GQ; Hu X; Cassady JM; Paige LA; Geahlen RL
J Pharm Sci; 1994 Feb; 83(2):233-8. PubMed ID: 8169796
[TBL] [Abstract][Full Text] [Related]
19. Genetic and biochemical studies of a mutant Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase, nmt72pLeu99-->Pro, that produces temperature-sensitive myristic acid auxotrophy.
Johnson DR; Duronio RJ; Langner CA; Rudnick DA; Gordon JI
J Biol Chem; 1993 Jan; 268(1):483-94. PubMed ID: 8416952
[TBL] [Abstract][Full Text] [Related]
20. Substrate specificity of Saccharomyces cerevisiae myristoyl-CoA: protein N-myristoyltransferase. Analysis of fatty acid analogs containing carbonyl groups, nitrogen heteroatoms, and nitrogen heterocycles in an in vitro enzyme assay and subsequent identification of inhibitors of human immunodeficiency virus I replication.
Devadas B; Lu T; Katoh A; Kishore NS; Wade AC; Mehta PP; Rudnick DA; Bryant ML; Adams SP; Li Q
J Biol Chem; 1992 Apr; 267(11):7224-39. PubMed ID: 1559967
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
