These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 9115986)

  • 1. Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-99.
    Sekar K; Yu BZ; Rogers J; Lutton J; Liu X; Chen X; Tsai MD; Jain MK; Sundaralingam M
    Biochemistry; 1997 Mar; 36(11):3104-14. PubMed ID: 9115986
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phospholipase A2 engineering. Deletion of the C-terminus segment changes substrate specificity and uncouples calcium and substrate binding at the zwitterionic interface.
    Huang B; Yu BZ; Rogers J; Byeon IJ; Sekar K; Chen X; Sundaralingam M; Tsai MD; Jain MK
    Biochemistry; 1996 Sep; 35(37):12164-74. PubMed ID: 8810924
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phospholipase A2 engineering. Probing the structural and functional roles of N-terminal residues with site-directed mutagenesis, X-ray, and NMR.
    Liu X; Zhu H; Huang B; Rogers J; Yu BZ; Kumar A; Jain MK; Sundaralingam M; Tsai MD
    Biochemistry; 1995 Jun; 34(22):7322-34. PubMed ID: 7779775
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural water.
    Kumar A; Sekharudu C; Ramakrishnan B; Dupureur CM; Zhu H; Tsai MD; Sundaralingam M
    Protein Sci; 1994 Nov; 3(11):2082-8. PubMed ID: 7703854
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phospholipase A2 engineering. Structural and functional roles of highly conserved active site residues tyrosine-52 and tyrosine-73.
    Dupureur CM; Yu BZ; Jain MK; Noel JP; Deng T; Li Y; Byeon IJ; Tsai MD
    Biochemistry; 1992 Jul; 31(28):6402-13. PubMed ID: 1633153
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Roles of surface hydrophobic residues in the interfacial catalysis of bovine pancreatic phospholipase A2.
    Lee BI; Yoon ET; Cho W
    Biochemistry; 1996 Apr; 35(13):4231-40. PubMed ID: 8672459
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural analysis of phospholipase A2 from functional perspective. 1. Functionally relevant solution structure and roles of the hydrogen-bonding network.
    Yuan C; Byeon IJ; Li Y; Tsai MD
    Biochemistry; 1999 Mar; 38(10):2909-18. PubMed ID: 10074343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phospholipase A2 engineering. X-ray structural and functional evidence for the interaction of lysine-56 with substrates.
    Noel JP; Bingman CA; Deng TL; Dupureur CM; Hamilton KJ; Jiang RT; Kwak JG; Sekharudu C; Sundaralingam M; Tsai MD
    Biochemistry; 1991 Dec; 30(51):11801-11. PubMed ID: 1751497
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of the Y52F/Y73F double mutant of phospholipase A2: increased hydrophobic interactions of the phenyl groups compensate for the disrupted hydrogen bonds of the tyrosines.
    Sekharudu C; Ramakrishnan B; Huang B; Jiang RT; Dupureur CM; Tsai MD; Sundaralingam M
    Protein Sci; 1992 Dec; 1(12):1585-94. PubMed ID: 1304890
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Contributions of residues of pancreatic phospholipase A2 to interfacial binding, catalysis, and activation.
    Yu BZ; Rogers J; Tsai MD; Pidgeon C; Jain MK
    Biochemistry; 1999 Apr; 38(15):4875-84. PubMed ID: 10200177
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of the complex of bovine pancreatic phospholipase A2 with the inhibitor 1-hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol,
    Sekar K; Eswaramoorthy S; Jain MK; Sundaralingam M
    Biochemistry; 1997 Nov; 36(46):14186-91. PubMed ID: 9369492
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-49.
    Li Y; Yu BZ; Zhu H; Jain MK; Tsai MD
    Biochemistry; 1994 Dec; 33(49):14714-22. PubMed ID: 7993900
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Active site of bee venom phospholipase A2: the role of histidine-34, aspartate-64 and tyrosine-87.
    Annand RR; Kontoyianni M; Penzotti JE; Dudler T; Lybrand TP; Gelb MH
    Biochemistry; 1996 Apr; 35(14):4591-601. PubMed ID: 8605210
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Suggestive evidence for the involvement of the second calcium and surface loop in interfacial binding: monoclinic and trigonal crystal structures of a quadruple mutant of phospholipase A2.
    Sekar K; Yogavel M; Kanaujia SP; Sharma A; Velmurugan D; Poi MJ; Dauter Z; Tsai MD
    Acta Crystallogr D Biol Crystallogr; 2006 Jul; 62(Pt 7):717-24. PubMed ID: 16790927
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Asp-49 is not an absolute prerequisite for the enzymic activity of low-M(r) phospholipases A2: purification, characterization and computer modelling of an enzymically active Ser-49 phospholipase A2, ecarpholin S, from the venom of Echis carinatus sochureki (saw-scaled viper).
    Polgár J; Magnenat EM; Peitsch MC; Wells TN; Clemetson KJ
    Biochem J; 1996 Nov; 319 ( Pt 3)(Pt 3):961-8. PubMed ID: 8921006
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A structural determinant of the unique interfacial binding mode of bovine pancreatic phospholipase A2.
    Lee BI; Dua R; Cho W
    Biochemistry; 1999 Jun; 38(24):7811-8. PubMed ID: 10387021
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phospholipase A2 engineering. The roles of disulfide bonds in structure, conformational stability, and catalytic function.
    Zhu H; Dupureur CM; Zhang X; Tsai MD
    Biochemistry; 1995 Nov; 34(46):15307-14. PubMed ID: 7578147
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-resolution refinement of orthorhombic bovine pancreatic phospholipase A2.
    Sekar K; Sundaralingam M
    Acta Crystallogr D Biol Crystallogr; 1999 Jan; 55(Pt 1):46-50. PubMed ID: 10089393
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kinetic and structural properties of disulfide engineered phospholipase A2: insight into the role of disulfide bonding patterns.
    Yu BZ; Pan YH; Janssen MJ; Bahnson BJ; Jain MK
    Biochemistry; 2005 Mar; 44(9):3369-79. PubMed ID: 15736947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure, function and interfacial allosterism in phospholipase A2: insight from the anion-assisted dimer.
    Bahnson BJ
    Arch Biochem Biophys; 2005 Jan; 433(1):96-106. PubMed ID: 15581569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.