These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 9116294)

  • 21. Reduced folate carrier mutations are not the mechanism underlying methotrexate resistance in childhood acute lymphoblastic leukemia.
    Kaufman Y; Drori S; Cole PD; Kamen BA; Sirota J; Ifergan I; Arush MW; Elhasid R; Sahar D; Kaspers GJ; Jansen G; Matherly LH; Rechavi G; Toren A; Assaraf YG
    Cancer; 2004 Feb; 100(4):773-82. PubMed ID: 14770434
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Methotrexate transport and resistance.
    Moscow JA
    Leuk Lymphoma; 1998 Jul; 30(3-4):215-24. PubMed ID: 9713954
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Role of the E45K-reduced folate carrier gene mutation in methotrexate resistance in human leukemia cells.
    Gifford AJ; Haber M; Witt TL; Whetstine JR; Taub JW; Matherly LH; Norris MD
    Leukemia; 2002 Dec; 16(12):2379-87. PubMed ID: 12454742
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Differential alterations of dihydrofolate reductase gene in human leukemia cell lines made resistant to various folate analogues.
    Miyachi H; Takemura Y; Kobayashi H; Ando K; Ando Y
    Jpn J Cancer Res; 1993 Jan; 84(1):9-12. PubMed ID: 8449831
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier.
    Wong SC; Zhang L; Witt TL; Proefke SA; Bhushan A; Matherly LH
    J Biol Chem; 1999 Apr; 274(15):10388-94. PubMed ID: 10187828
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells.
    Zhao R; Seither R; Brigle KE; Sharina IG; Wang PJ; Goldman ID
    J Biol Chem; 1997 Aug; 272(34):21207-12. PubMed ID: 9261128
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The influence of drug-exposure conditions on the development of resistance to methotrexate or ZD1694 in cultured human leukaemia cells.
    Takemura Y; Kobayashi H; Gibson W; Kimbell R; Miyachi H; Jackman AL
    Int J Cancer; 1996 Mar; 66(1):29-36. PubMed ID: 8608962
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Role of the C-terminus and the long cytoplasmic loop in reduced folate carrier expression and function.
    Sharina IG; Zhao R; Wang Y; Babani S; Goldman ID
    Biochem Pharmacol; 2002 May; 63(9):1717-24. PubMed ID: 12007575
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Clustering of mutations in the first transmembrane domain of the human reduced folate carrier in GW1843U89-resistant leukemia cells with impaired antifolate transport and augmented folate uptake.
    Drori S; Jansen G; Mauritz R; Peters GJ; Assaraf YG
    J Biol Chem; 2000 Oct; 275(40):30855-63. PubMed ID: 10899164
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Microsatellite instability and clonal heterogeneity of MDR1 messenger RNA expression in trimetrexate-resistant human leukemia MOLT-3 cells developed in thymidine.
    Miyachi H; Ma L; Takemura Y; Kobayashi H; Hirahara I; Sonehara H; Ando Y
    Int J Cancer; 1999 Jul; 82(1):63-9. PubMed ID: 10360822
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Biological activity and intracellular metabolism of ZD1694 in human leukemia cell lines with different resistance mechanisms to antifolate drugs.
    Takemura Y; Kobayashi H; Miyachi H; Gibson W; Kimbell R; Jackman AL
    Jpn J Cancer Res; 1996 Jul; 87(7):773-80. PubMed ID: 8698629
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Disparate mechanisms of antifolate resistance provoked by methotrexate and its metabolite 7-hydroxymethotrexate in leukemia cells: implications for efficacy of methotrexate therapy.
    Fotoohi K; Jansen G; Assaraf YG; Rothem L; Stark M; Kathmann I; Gregorczyk J; Peters GJ; Albertioni F
    Blood; 2004 Dec; 104(13):4194-201. PubMed ID: 15308564
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A prominent low-pH methotrexate transport activity in human solid tumors: contribution to the preservation of methotrexate pharmacologic activity in HeLa cells lacking the reduced folate carrier.
    Zhao R; Gao F; Hanscom M; Goldman ID
    Clin Cancer Res; 2004 Jan; 10(2):718-27. PubMed ID: 14760095
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines.
    Rothem L; Ifergan I; Kaufman Y; Priest DG; Jansen G; Assaraf YG
    Biochem J; 2002 Nov; 367(Pt 3):741-50. PubMed ID: 12139489
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Membrane protein changes in an L1210 leukemia cell line with a translocation defect in the methotrexate-tetrahydrofolate cofactor transport carrier.
    Schuetz JD; Westin EH; Matherly LH; Pincus R; Swerdlow PS; Goldman ID
    J Biol Chem; 1989 Sep; 264(27):16261-7. PubMed ID: 2777791
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
    Rots MG; Pieters R; Kaspers GJ; van Zantwijk CH; Noordhuis P; Mauritz R; Veerman AJ; Jansen G; Peters GJ
    Blood; 1999 Feb; 93(3):1067-74. PubMed ID: 9920857
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Concentrating capacity of the human reduced folate carrier (hRFC1) in human ZR-75 breast cancer cell lines.
    Sharif KA; Moscow JA; Goldman ID
    Biochem Pharmacol; 1998 May; 55(10):1683-9. PubMed ID: 9634005
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Establishment of methotrexate-resistant human acute lymphoblastic leukemia cells in culture and effects of folate antagonists.
    Ohnoshi T; Ohnuma T; Takahashi I; Scanlon K; Kamen BA; Holland JF
    Cancer Res; 1982 May; 42(5):1655-60. PubMed ID: 6978176
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Coexistence of multiple mechanisms of PT523 resistance in human leukemia cells harboring 3 reduced folate carrier alleles: transcriptional silencing, inactivating mutations, and allele loss.
    Kaufman Y; Ifergan I; Rothem L; Jansen G; Assaraf YG
    Blood; 2006 Apr; 107(8):3288-94. PubMed ID: 16368880
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Variable expression of the folylpolyglutamate synthetase gene at the level of mRNA transcription in human leukemia cell lines sensitive, or made resistant, to various antifolate drugs.
    Takemura Y; Kobayashi H; Miyachi H
    Anticancer Drugs; 1999 Aug; 10(7):677-83. PubMed ID: 10507318
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.