BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

441 related articles for article (PubMed ID: 9120387)

  • 1. Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells.
    Szabo SJ; Dighe AS; Gubler U; Murphy KM
    J Exp Med; 1997 Mar; 185(5):817-24. PubMed ID: 9120387
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective expression of an interleukin-12 receptor component by human T helper 1 cells.
    Rogge L; Barberis-Maino L; Biffi M; Passini N; Presky DH; Gubler U; Sinigaglia F
    J Exp Med; 1997 Mar; 185(5):825-31. PubMed ID: 9120388
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cutting edge: ectopic expression of the IL-12 receptor-beta 2 in developing and committed Th2 cells does not affect the production of IL-4 or induce the production of IFN-gamma.
    Heath VL; Showe L; Crain C; Barrat FJ; Trinchieri G; O'Garra A
    J Immunol; 2000 Mar; 164(6):2861-5. PubMed ID: 10706670
    [TBL] [Abstract][Full Text] [Related]  

  • 4. T helper differentiation proceeds through Stat1-dependent, Stat4-dependent and Stat4-independent phases.
    Murphy KM; Ouyang W; Szabo SJ; Jacobson NG; Guler ML; Gorham JD; Gubler U; Murphy TL
    Curr Top Microbiol Immunol; 1999; 238():13-26. PubMed ID: 10087648
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lack of IL-12 signaling in human allergen-specific Th2 cells.
    Hilkens CM; Messer G; Tesselaar K; van Rietschoten AG; Kapsenberg ML; Wierenga EA
    J Immunol; 1996 Nov; 157(10):4316-21. PubMed ID: 8906805
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Depressed IL-12-mediated signal transduction in T cells from patients with Sézary syndrome is associated with the absence of IL-12 receptor beta 2 mRNA and highly reduced levels of STAT4.
    Showe LC; Fox FE; Williams D; Au K; Niu Z; Rook AH
    J Immunol; 1999 Oct; 163(7):4073-9. PubMed ID: 10491012
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression.
    Smits HH; van Rietschoten JG; Hilkens CM; Sayilir R; Stiekema F; Kapsenberg ML; Wierenga EA
    Eur J Immunol; 2001 Apr; 31(4):1055-65. PubMed ID: 11298330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling.
    Nishikomori R; Usui T; Wu CY; Morinobu A; O'Shea JJ; Strober W
    J Immunol; 2002 Oct; 169(8):4388-98. PubMed ID: 12370372
    [TBL] [Abstract][Full Text] [Related]  

  • 9. STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation.
    Morinobu A; Gadina M; Strober W; Visconti R; Fornace A; Montagna C; Feldman GM; Nishikomori R; O'Shea JJ
    Proc Natl Acad Sci U S A; 2002 Sep; 99(19):12281-6. PubMed ID: 12213961
    [TBL] [Abstract][Full Text] [Related]  

  • 10. IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites.
    Wu C; Wang X; Gadina M; O'Shea JJ; Presky DH; Magram J
    J Immunol; 2000 Dec; 165(11):6221-8. PubMed ID: 11086056
    [TBL] [Abstract][Full Text] [Related]  

  • 11. T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells.
    Afkarian M; Sedy JR; Yang J; Jacobson NG; Cereb N; Yang SY; Murphy TL; Murphy KM
    Nat Immunol; 2002 Jun; 3(6):549-57. PubMed ID: 12006974
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antibodies to the IL-12 receptor beta 2 chain mark human Th1 but not Th2 cells in vitro and in vivo.
    Rogge L; Papi A; Presky DH; Biffi M; Minetti LJ; Miotto D; Agostini C; Semenzato G; Fabbri LM; Sinigaglia F
    J Immunol; 1999 Apr; 162(7):3926-32. PubMed ID: 10201911
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Developmental commitment to the Th2 lineage by extinction of IL-12 signaling.
    Szabo SJ; Jacobson NG; Dighe AS; Gubler U; Murphy KM
    Immunity; 1995 Jun; 2(6):665-75. PubMed ID: 7796298
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dominance of IL-12 over IL-4 in gamma delta T cell differentiation leads to default production of IFN-gamma: failure to down-regulate IL-12 receptor beta 2-chain expression.
    Yin Z; Zhang DH; Welte T; Bahtiyar G; Jung S; Liu L; Fu XY; Ray A; Craft J
    J Immunol; 2000 Mar; 164(6):3056-64. PubMed ID: 10706694
    [TBL] [Abstract][Full Text] [Related]  

  • 15. IFN-gamma up-regulation of IL-12 beta 2 receptor is associated with experimental autoimmune uveitis susceptible B10.A mice, but not in EAU resistant BALB/c mice.
    Wu Y; Lin Y; Hou W; Wang Y; Sun B
    J Neuroimmunol; 2003 Apr; 137(1-2):154-63. PubMed ID: 12667660
    [TBL] [Abstract][Full Text] [Related]  

  • 16. T cell genetic background determines maintenance of IL-12 signaling: effects on BALB/c and B10.D2 T helper cell type 1 phenotype development.
    Güler ML; Jacobson NG; Gubler U; Murphy KM
    J Immunol; 1997 Aug; 159(4):1767-74. PubMed ID: 9257839
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IL-2 receptor blockade inhibits late, but not early, IFN-gamma and CD40 ligand expression in human T cells: disruption of both IL-12-dependent and -independent pathways of IFN-gamma production.
    McDyer JF; Li Z; John S; Yu X; Wu CY; Ragheb JA
    J Immunol; 2002 Sep; 169(5):2736-46. PubMed ID: 12193748
    [TBL] [Abstract][Full Text] [Related]  

  • 18. T helper type 2 cell differentiation occurs in the presence of interleukin 12 receptor beta2 chain expression and signaling.
    Nishikomori R; Ehrhardt RO; Strober W
    J Exp Med; 2000 Mar; 191(5):847-58. PubMed ID: 10704465
    [TBL] [Abstract][Full Text] [Related]  

  • 19. T(h)1/T(h)2 cell differentiation of developing CD4 single-positive thymocytes.
    Kikkawa E; Yamashita M; Kimura M; Omori M; Sugaya K; Shimizu C; Katsumoto T; Ikekita M; Taniguchi M; Nakayama T
    Int Immunol; 2002 Aug; 14(8):943-51. PubMed ID: 12147631
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment.
    Durali D; de Goër de Herve MG; Giron-Michel J; Azzarone B; Delfraissy JF; Taoufik Y
    Blood; 2003 Dec; 102(12):4084-9. PubMed ID: 12893768
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.