BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 9121365)

  • 41. Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain.
    Furukawa K; Sopher BL; Rydel RE; Begley JG; Pham DG; Martin GM; Fox M; Mattson MP
    J Neurochem; 1996 Nov; 67(5):1882-96. PubMed ID: 8863493
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein.
    Cordy JM; Hussain I; Dingwall C; Hooper NM; Turner AJ
    Proc Natl Acad Sci U S A; 2003 Sep; 100(20):11735-40. PubMed ID: 14504402
    [TBL] [Abstract][Full Text] [Related]  

  • 43. The utility of muscarinic agonists in the treatment of Alzheimer's disease.
    Messer WS
    J Mol Neurosci; 2002; 19(1-2):187-93. PubMed ID: 12212779
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.
    Parvathy S; Hussain I; Karran EH; Turner AJ; Hooper NM
    Biochemistry; 1999 Jul; 38(30):9728-34. PubMed ID: 10423252
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Characterization of beta-amyloid peptide precursor processing by the yeast Yap3 and Mkc7 proteases.
    Zhang W; Espinoza D; Hines V; Innis M; Mehta P; Miller DL
    Biochim Biophys Acta; 1997 Nov; 1359(2):110-22. PubMed ID: 9409808
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
    Gandhi S; Refolo LM; Sambamurti K
    J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Double-Edged Roles of Nitric Oxide Signaling on APP Processing and Amyloid-β Production In Vitro: Preliminary Evidence from Sodium Nitroprusside.
    Cai ZX; Guo HS; Wang C; Wei M; Cheng C; Yang ZF; Chen YW; Le WD; Li S
    Neurotox Res; 2016 Jan; 29(1):21-34. PubMed ID: 26429731
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Memory-related task performance by aged rhesus monkeys administered the muscarinic M(1)-preferring agonist, talsaclidine.
    Terry AV; Buccafusco JJ; Borsini F; Leusch A
    Psychopharmacology (Berl); 2002 Jul; 162(3):292-300. PubMed ID: 12122487
    [TBL] [Abstract][Full Text] [Related]  

  • 50. AF150(S) and AF267B: M1 muscarinic agonists as innovative therapies for Alzheimer's disease.
    Fisher A; Brandeis R; Bar-Ner RH; Kliger-Spatz M; Natan N; Sonego H; Marcovitch I; Pittel Z
    J Mol Neurosci; 2002; 19(1-2):145-53. PubMed ID: 12212772
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Treatment with the selective muscarinic agonist talsaclidine decreases cerebrospinal fluid levels of total amyloid beta-peptide in patients with Alzheimer's disease.
    Hock C; Maddalena A; Heuser I; Naber D; Oertel W; von der Kammer H; Wienrich M; Raschig A; Deng M; Growdon JH; Nitsch RM
    Ann N Y Acad Sci; 2000; 920():285-91. PubMed ID: 11193166
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease.
    Lammich S; Kojro E; Postina R; Gilbert S; Pfeiffer R; Jasionowski M; Haass C; Fahrenholz F
    Proc Natl Acad Sci U S A; 1999 Mar; 96(7):3922-7. PubMed ID: 10097139
    [TBL] [Abstract][Full Text] [Related]  

  • 53. The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein.
    Petanceska SS; Gandy S
    J Neurochem; 1999 Dec; 73(6):2316-20. PubMed ID: 10582589
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Short-term interleukin-1(beta) increases the release of secreted APP(alpha) via MEK1/2-dependent and JNK-dependent alpha-secretase cleavage in neuroglioma U251 cells.
    Ma G; Chen S; Wang X; Ba M; Yang H; Lu G
    J Neurosci Res; 2005 Jun; 80(5):683-92. PubMed ID: 15880353
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Enhancement of alpha-secretase cleavage of amyloid precursor protein by a metalloendopeptidase nardilysin.
    Hiraoka Y; Ohno M; Yoshida K; Okawa K; Tomimoto H; Kita T; Nishi E
    J Neurochem; 2007 Sep; 102(5):1595-1605. PubMed ID: 17555553
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Therapeutic strategies in Alzheimer's disease: M1 muscarinic agonists.
    Fisher A
    Jpn J Pharmacol; 2000 Oct; 84(2):101-12. PubMed ID: 11128032
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Intracellular domain generation of amyloid precursor protein by epsilon-cleavage depends on C-terminal fragment by alpha-secretase cleavage.
    Kume H; Maruyama K; Kametani F
    Int J Mol Med; 2004 Jan; 13(1):121-5. PubMed ID: 14654982
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Iron levels modulate alpha-secretase cleavage of amyloid precursor protein.
    Bodovitz S; Falduto MT; Frail DE; Klein WL
    J Neurochem; 1995 Jan; 64(1):307-15. PubMed ID: 7798927
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Novel alpha-secretase cleavage of Alzheimer's amyloid beta precursor protein in the endoplasmic reticulum of COS7 cells.
    Shin RW; Saido TC; Maeda M; Kitamoto T
    Neurosci Lett; 2005 Mar; 376(1):14-9. PubMed ID: 15694266
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Regulation of APP cleavage by alpha-, beta- and gamma-secretases.
    Nunan J; Small DH
    FEBS Lett; 2000 Oct; 483(1):6-10. PubMed ID: 11033346
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.