BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 9122198)

  • 1. Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain.
    Drachman JG; Kaushansky K
    Proc Natl Acad Sci U S A; 1997 Mar; 94(6):2350-5. PubMed ID: 9122198
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation.
    Morita H; Tahara T; Matsumoto A; Kato T; Miyazaki H; Ohashi H
    FEBS Lett; 1996 Oct; 395(2-3):228-34. PubMed ID: 8898102
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tyrosine-599 of the c-Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiation.
    Alexander WS; Maurer AB; Novak U; Harrison-Smith M
    EMBO J; 1996 Dec; 15(23):6531-40. PubMed ID: 8978680
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of thrombopoietin, interleukin-3 and the kinase inhibitor K-252a on growth and polyploidization of the megakaryocytic cell line M-07e.
    Quentmeier H; Zaborski M; Drexler HG
    Leukemia; 1998 Oct; 12(10):1603-11. PubMed ID: 9766506
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Involvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line.
    Matsumura I; Nakajima K; Wakao H; Hattori S; Hashimoto K; Sugahara H; Kato T; Miyazaki H; Hirano T; Kanakura Y
    Mol Cell Biol; 1998 Jul; 18(7):4282-90. PubMed ID: 9632812
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel MPL point mutation resulting in thrombopoietin-independent activation.
    Abe M; Suzuki K; Inagaki O; Sassa S; Shikama H
    Leukemia; 2002 Aug; 16(8):1500-6. PubMed ID: 12145691
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases.
    Sattler M; Durstin MA; Frank DA; Okuda K; Kaushansky K; Salgia R; Griffin JD
    Exp Hematol; 1995 Aug; 23(9):1040-8. PubMed ID: 7543416
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differentiation induced by the c-Mpl cytokine receptor is blocked by mutant Shc adaptor protein.
    Hill RJ; Zozulya S; Lu YL; Hollenbach PW; Joyce-Shaikh B; Bogenberger J; Gishizky ML
    Cell Growth Differ; 1996 Sep; 7(9):1125-34. PubMed ID: 8877093
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential signalling of NH2-terminal flag-labelled thrombopoietin receptor activated by TPO or anti-FLAG antibodies.
    Millot GA; Vainchenker W; Duménil D; Svinarchuk F
    Cell Signal; 2004 Mar; 16(3):355-63. PubMed ID: 14687665
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional regions of the mouse thrombopoietin receptor cytoplasmic domain: evidence for a critical region which is involved in differentiation and can be complemented by erythropoietin.
    Porteu F; Rouyez MC; Cocault L; Bénit L; Charon M; Picard F; Gisselbrecht S; Souyri M; Dusanter-Fourt I
    Mol Cell Biol; 1996 May; 16(5):2473-82. PubMed ID: 8628315
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A new feature of Mpl receptor: ligand-induced transforming activity in FRE rat fibroblasts.
    Challier C; Cocault L; Flon M; Pauchard M; Porteu F; Gisselbrecht S; Souyri M
    Oncogene; 2000 Apr; 19(16):2033-42. PubMed ID: 10803464
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl.
    Drachman JG; Griffin JD; Kaushansky K
    J Biol Chem; 1995 Mar; 270(10):4979-82. PubMed ID: 7534285
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
    Pallard C; Gouilleux F; Bénit L; Cocault L; Souyri M; Levy D; Groner B; Gisselbrecht S; Dusanter-Fourt I
    EMBO J; 1995 Jun; 14(12):2847-56. PubMed ID: 7796811
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thrombopoietin induces tyrosine phosphorylation of a common beta subunit of GM-CSF receptor and its association with Stat5 in TF-1/TPO cells.
    Ooi J; Tojo A; Asano S; Sato Y; Oka Y
    Biochem Biophys Res Commun; 1998 May; 246(1):132-6. PubMed ID: 9600081
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thrombopoietin induces an SH2-containing protein, CIS1, which binds to Mpl: involvement of the ubiquitin proteosome pathway.
    Okabe S; Tauchi T; Morita H; Ohashi H; Yoshimura A; Ohyashiki K
    Exp Hematol; 1999 Oct; 27(10):1542-7. PubMed ID: 10517496
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A structure-function analysis of serine/threonine phosphorylation of the thrombopoietin receptor, c-Mpl.
    Miyakawa Y; Drachman JG; Gallis B; Kaushansky A; Kaushansky K
    J Biol Chem; 2000 Oct; 275(41):32214-9. PubMed ID: 10918061
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thrombopoietin (TPO) induces tyrosine phosphorylation and activation of STAT5 and STAT3.
    Bacon CM; Tortolani PJ; Shimosaka A; Rees RC; Longo DL; O'Shea JJ
    FEBS Lett; 1995 Aug; 370(1-2):63-8. PubMed ID: 7544303
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Establishment and characterization of the thrombopoietin-dependent megakaryocytic cell line, UT-7/TPO.
    Komatsu N; Kunitama M; Yamada M; Hagiwara T; Kato T; Miyazaki H; Eguchi M; Yamamoto M; Miura Y
    Blood; 1996 Jun; 87(11):4552-60. PubMed ID: 8639823
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A non-peptide compound which can mimic the effect of thrombopoietin via c-Mpl.
    Kimura T; Kaburaki H; Tsujino T; Ikeda Y; Kato H; Watanabe Y
    FEBS Lett; 1998 May; 428(3):250-4. PubMed ID: 9654143
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Studies with chimeric Mpl/JAK2 receptors indicate that both JAK2 and the membrane-proximal domain of Mpl are required for cellular proliferation.
    Drachman JG; Miyakawa Y; Luthi JN; Dahlen DD; Raney A; Geddis AE; Kaushansky K
    J Biol Chem; 2002 Jun; 277(26):23544-53. PubMed ID: 11980901
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.