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6. Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites. Urbatsch IL; Beaudet L; Carrier I; Gros P Biochemistry; 1998 Mar; 37(13):4592-602. PubMed ID: 9521779 [TBL] [Abstract][Full Text] [Related]
7. Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis. Sauna ZE; Smith MM; Muller M; Ambudkar SV J Biol Chem; 2001 Jun; 276(24):21199-208. PubMed ID: 11287418 [TBL] [Abstract][Full Text] [Related]
8. P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites. Senior AE; Bhagat S Biochemistry; 1998 Jan; 37(3):831-6. PubMed ID: 9454572 [TBL] [Abstract][Full Text] [Related]
9. Drug binding and nucleotide hydrolyzability are essential requirements in the vanadate-induced inhibition of the human P-glycoprotein ATPase. Rao US Biochemistry; 1998 Oct; 37(42):14981-8. PubMed ID: 9778376 [TBL] [Abstract][Full Text] [Related]
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12. Effect of modulators on the ATPase activity and vanadate nucleotide trapping of human P-glycoprotein. Shepard RL; Winter MA; Hsaio SC; Pearce HL; Beck WT; Dantzig AH Biochem Pharmacol; 1998 Sep; 56(6):719-27. PubMed ID: 9751076 [TBL] [Abstract][Full Text] [Related]
13. Both ATP sites of human P-glycoprotein are essential but not symmetric. Hrycyna CA; Ramachandra M; Germann UA; Cheng PW; Pastan I; Gottesman MM Biochemistry; 1999 Oct; 38(42):13887-99. PubMed ID: 10529234 [TBL] [Abstract][Full Text] [Related]
14. Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains. Liu R; Sharom FJ Biochemistry; 1996 Sep; 35(36):11865-73. PubMed ID: 8794769 [TBL] [Abstract][Full Text] [Related]
15. 8-Azido-adenine nucleotides as substrates of ecto-nucleotidases in chromaffin cells: inhibitory effect of photoactivation. Rodríguez-Pascual F; Torres M; Miras-Portugal MT Arch Biochem Biophys; 1993 Nov; 306(2):420-6. PubMed ID: 8215445 [TBL] [Abstract][Full Text] [Related]
16. Nucleotide-induced conformational changes in P-glycoprotein and in nucleotide binding site mutants monitored by trypsin sensitivity. Julien M; Gros P Biochemistry; 2000 Apr; 39(15):4559-68. PubMed ID: 10758006 [TBL] [Abstract][Full Text] [Related]
17. Modulator-induced interference in functional cross talk between the substrate and the ATP sites of human P-glycoprotein. Maki N; Moitra K; Silver C; Ghosh P; Chattopadhyay A; Dey S Biochemistry; 2006 Feb; 45(8):2739-51. PubMed ID: 16489767 [TBL] [Abstract][Full Text] [Related]
18. Photolabeling of mitochondrial F1-H+ATPase by 2-azido[3H]ADP and 8-azido[3H]ADP entrapped as fluorometal complexes into the catalytic sites of the enzyme. Garin J; Vinçon M; Gagnon J; Vignais P Biochemistry; 1994 Mar; 33(12):3772-7. PubMed ID: 8142378 [TBL] [Abstract][Full Text] [Related]
19. Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state. Ramachandra M; Ambudkar SV; Chen D; Hrycyna CA; Dey S; Gottesman MM; Pastan I Biochemistry; 1998 Apr; 37(14):5010-9. PubMed ID: 9538020 [TBL] [Abstract][Full Text] [Related]
20. ATP hydrolysis by multidrug-resistance protein from Chinese hamster ovary cells. Senior AE; al-Shawi MK; Urbatsch IL J Bioenerg Biomembr; 1995 Feb; 27(1):31-6. PubMed ID: 7629049 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]