183 related articles for article (PubMed ID: 9144240)
1. Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C.
Walter J; Grünberg J; Capell A; Pesold B; Schindzielorz A; Citron M; Mendla K; George-Hyslop PS; Multhaup G; Selkoe DJ; Haass C
Proc Natl Acad Sci U S A; 1997 May; 94(10):5349-54. PubMed ID: 9144240
[TBL] [Abstract][Full Text] [Related]
2. Proteolytic fragments of the Alzheimer's disease associated presenilins-1 and -2 are phosphorylated in vivo by distinct cellular mechanisms.
Walter J; Grünberg J; Schindzielorz A; Haass C
Biochemistry; 1998 Apr; 37(17):5961-7. PubMed ID: 9558331
[TBL] [Abstract][Full Text] [Related]
3. Alzheimer's disease associated presenilin-1 holoprotein and its 18-20 kDa C-terminal fragment are death substrates for proteases of the caspase family.
Grunberg J; Walter J; Loetscher H; Deuschle U; Jacobsen H; Haass C
Biochemistry; 1998 Feb; 37(8):2263-70. PubMed ID: 9485372
[TBL] [Abstract][Full Text] [Related]
4. The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex.
Capell A; Grünberg J; Pesold B; Diehlmann A; Citron M; Nixon R; Beyreuther K; Selkoe DJ; Haass C
J Biol Chem; 1998 Feb; 273(6):3205-11. PubMed ID: 9452432
[TBL] [Abstract][Full Text] [Related]
5. The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum.
Walter J; Capell A; Grünberg J; Pesold B; Schindzielorz A; Prior R; Podlisny MB; Fraser P; Hyslop PS; Selkoe DJ; Haass C
Mol Med; 1996 Nov; 2(6):673-91. PubMed ID: 8972483
[TBL] [Abstract][Full Text] [Related]
6. Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis.
Walter J; Schindzielorz A; Grünberg J; Haass C
Proc Natl Acad Sci U S A; 1999 Feb; 96(4):1391-6. PubMed ID: 9990034
[TBL] [Abstract][Full Text] [Related]
7. Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations.
Okochi M; Ishii K; Usami M; Sahara N; Kametani F; Tanaka K; Fraser PE; Ikeda M; Saunders AM; Hendriks L; Shoji SI; Nee LE; Martin JJ; Van Broeckhoven C; St George-Hyslop PH; Roses AD; Mori H
FEBS Lett; 1997 Nov; 418(1-2):162-6. PubMed ID: 9414118
[TBL] [Abstract][Full Text] [Related]
8. The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.
Saura CA; Tomita T; Soriano S; Takahashi M; Leem JY; Honda T; Koo EH; Iwatsubo T; Thinakaran G
J Biol Chem; 2000 Jun; 275(22):17136-42. PubMed ID: 10748144
[TBL] [Abstract][Full Text] [Related]
9. Evidence for phosphorylation and oligomeric assembly of presenilin 1.
Seeger M; Nordstedt C; Petanceska S; Kovacs DM; Gouras GK; Hahne S; Fraser P; Levesque L; Czernik AJ; George-Hyslop PS; Sisodia SS; Thinakaran G; Tanzi RE; Greengard P; Gandy S
Proc Natl Acad Sci U S A; 1997 May; 94(10):5090-4. PubMed ID: 9144195
[TBL] [Abstract][Full Text] [Related]
10. Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2.
Choi EK; Zaidi NF; Miller JS; Crowley AC; Merriam DE; Lilliehook C; Buxbaum JD; Wasco W
J Biol Chem; 2001 Jun; 276(22):19197-204. PubMed ID: 11278424
[TBL] [Abstract][Full Text] [Related]
11. Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta-peptide production and requires a critical aspartate residue for its function in amyloidogenesis.
Leimer U; Lun K; Romig H; Walter J; Grünberg J; Brand M; Haass C
Biochemistry; 1999 Oct; 38(41):13602-9. PubMed ID: 10521267
[TBL] [Abstract][Full Text] [Related]
12. Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.
Podlisny MB; Citron M; Amarante P; Sherrington R; Xia W; Zhang J; Diehl T; Levesque G; Fraser P; Haass C; Koo EH; Seubert P; St George-Hyslop P; Teplow DB; Selkoe DJ
Neurobiol Dis; 1997; 3(4):325-37. PubMed ID: 9173929
[TBL] [Abstract][Full Text] [Related]
13. Different effects of Alzheimer-associated mutations of presenilin 1 on its processing.
Murayama O; Honda T; Mercken M; Murayama M; Yasutake K; Nihonmatsu N; Nakazato Y; Michel G; Song S; Sato K; Takahashi H; Takashima A
Neurosci Lett; 1997 Jun; 229(1):61-4. PubMed ID: 9224802
[TBL] [Abstract][Full Text] [Related]
14. Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein.
Laudon H; Mathews PM; Karlström H; Bergman A; Farmery MR; Nixon RA; Winblad B; Gandy SE; Lendahl U; Lundkvist J; Näslund J
J Neurochem; 2004 Apr; 89(1):44-53. PubMed ID: 15030388
[TBL] [Abstract][Full Text] [Related]
15. Subcellular localization of presenilin 2 endoproteolytic C-terminal fragments.
Tekirian TL; Merriam DE; Marshansky V; Miller J; Crowley AC; Chan H; Ausiello D; Brown D; Buxbaum JD; Xia W; Wasco W
Brain Res Mol Brain Res; 2001 Nov; 96(1-2):14-20. PubMed ID: 11731004
[TBL] [Abstract][Full Text] [Related]
16. The influence of endoproteolytic processing of familial Alzheimer's disease presenilin 2 on abeta42 amyloid peptide formation.
Jacobsen H; Reinhardt D; Brockhaus M; Bur D; Kocyba C; Kurt H; Grim MG; Baumeister R; Loetscher H
J Biol Chem; 1999 Dec; 274(49):35233-9. PubMed ID: 10575009
[TBL] [Abstract][Full Text] [Related]
17. Evidence that intramolecular associations between presenilin domains are obligatory for endoproteolytic processing.
Saura CA; Tomita T; Davenport F; Harris CL; Iwatsubo T; Thinakaran G
J Biol Chem; 1999 May; 274(20):13818-23. PubMed ID: 10318786
[TBL] [Abstract][Full Text] [Related]
18. Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation.
Steiner H; Capell A; Pesold B; Citron M; Kloetzel PM; Selkoe DJ; Romig H; Mendla K; Haass C
J Biol Chem; 1998 Nov; 273(48):32322-31. PubMed ID: 9822712
[TBL] [Abstract][Full Text] [Related]
19. A novel presenilin-2 splice variant in human Alzheimer's disease brain tissue.
Sato N; Hori O; Yamaguchi A; Lambert JC; Chartier-Harlin MC; Robinson PA; Delacourte A; Schmidt AM; Furuyama T; Imaizumi K; Tohyama M; Takagi T
J Neurochem; 1999 Jun; 72(6):2498-505. PubMed ID: 10349860
[TBL] [Abstract][Full Text] [Related]
20. Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing.
Baumeister R; Leimer U; Zweckbronner I; Jakubek C; Grünberg J; Haass C
Genes Funct; 1997 Apr; 1(2):149-59. PubMed ID: 9680315
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
