476 related articles for article (PubMed ID: 9144460)
1. The area under the concentration-time curve of all-trans-retinoic acid is the most suitable pharmacokinetic correlate to the embryotoxicity of this retinoid in the rat.
Tzimas G; Thiel R; Chahoud I; Nau H
Toxicol Appl Pharmacol; 1997 Apr; 143(2):436-44. PubMed ID: 9144460
[TBL] [Abstract][Full Text] [Related]
2. Retinoid metabolism and transplacental pharmacokinetics in the cynomolgus monkey following a nonteratogenic dosing regimen with all-trans-retinoic acid.
Tzimas G; Nau H; Hendrickx AG; Peterson PE; Hummler H
Teratology; 1996 Nov; 54(5):255-65. PubMed ID: 9035347
[TBL] [Abstract][Full Text] [Related]
3. Teratogenicity and transplacental pharmacokinetics of 13-cis-retinoic acid in rabbits.
Eckhoff C; Chari S; Kromka M; Staudner H; Juhasz L; Rudiger H; Agnish N
Toxicol Appl Pharmacol; 1994 Mar; 125(1):34-41. PubMed ID: 8128493
[TBL] [Abstract][Full Text] [Related]
4. Teratogenicity of the 13-cis and all-trans-isomers of the aromatic retinoid etretin: correlation to transplacental pharmacokinetics in mice during organogenesis after a single oral dose.
Löfberg B; Chahoud I; Bochert G; Nau H
Teratology; 1990 Jun; 41(6):707-16. PubMed ID: 2141193
[TBL] [Abstract][Full Text] [Related]
5. Single versus multiple dose administration of all-trans-retinoic acid during organogenesis: differential metabolism and transplacental kinetics in rat and rabbit.
Collins MD; Tzimas G; Bürgin H; Hummler H; Nau H
Toxicol Appl Pharmacol; 1995 Jan; 130(1):9-18. PubMed ID: 7839374
[TBL] [Abstract][Full Text] [Related]
6. All-trans-retinoyl-beta-glucuronide is a potent teratogen in the mouse because of extensive metabolism to all-trans-retinoic acid.
Nau H; Elmazar MM; Rühl R; Thiel R; Sass JO
Teratology; 1996 Sep; 54(3):150-6. PubMed ID: 8987158
[TBL] [Abstract][Full Text] [Related]
7. Comparative teratology and transplacental pharmacokinetics of all-trans-retinoic acid, 13-cis-retinoic acid, and retinyl palmitate following daily administrations in rats.
Collins MD; Tzimas G; Hummler H; Bürgin H; Nau H
Toxicol Appl Pharmacol; 1994 Jul; 127(1):132-44. PubMed ID: 8048045
[TBL] [Abstract][Full Text] [Related]
8. All-trans-retinoic acid in maternal plasma and teratogenicity in rats and rabbits.
Tembe EA; Honeywell R; Buss NE; Renwick AG
Toxicol Appl Pharmacol; 1996 Dec; 141(2):456-72. PubMed ID: 8975771
[TBL] [Abstract][Full Text] [Related]
9. Gestational age dependency in the prenatal toxicity and in the disposition kinetics of the novel anticonvulsant HEPP (D,L-3-hydroxy-3-ethyl-3-phenylpropionamide) after subcutaneous administration in pregnant rats.
Gómez-Martínez LE
Int J Toxicol; 2007; 26(3):237-46. PubMed ID: 17564905
[TBL] [Abstract][Full Text] [Related]
10. Identification of 9,13-dicis-retinoic acid as a major plasma metabolite of 9-cis-retinoic acid and limited transfer of 9-cis-retinoic acid and 9,13-dicis-retinoic acid to the mouse and rat embryos.
Tzimas G; Sass JO; Wittfoht W; Elmazar MM; Ehlers K; Nau H
Drug Metab Dispos; 1994; 22(6):928-36. PubMed ID: 7895612
[TBL] [Abstract][Full Text] [Related]
11. Comparative teratogenicity and metabolism of all-trans retinoic acid, all-trans retinoyl beta-glucose, and all-trans retinoyl beta-glucuronide in pregnant Sprague-Dawley rats.
Gunning DB; Barua AB; Olson JA
Teratology; 1993 Jan; 47(1):29-36. PubMed ID: 8475455
[TBL] [Abstract][Full Text] [Related]
12. Maternal toxicokinetics, metabolism, and embryo exposure following a teratogenic dosing regimen with 13-cis-retinoic acid (isotretinoin) in the cynomolgus monkey.
Hummler H; Hendrickx AG; Nau H
Teratology; 1994 Sep; 50(3):184-93. PubMed ID: 7871482
[TBL] [Abstract][Full Text] [Related]
13. Differences in the pharmacokinetic properties of orally administered all-trans-retinoic acid and 9-cis-retinoic acid in the plasma of nude mice.
Achkar CC; Bentel JM; Boylan JF; Scher HI; Gudas LJ; Miller WH
Drug Metab Dispos; 1994; 22(3):451-8. PubMed ID: 8070324
[TBL] [Abstract][Full Text] [Related]
14. Distribution, teratogenicity, and embryonic delivered dose of retinoid Ro 23-9223.
Willhite CC; Lovey A; Eckhoff C
Toxicol Appl Pharmacol; 2000 Apr; 164(2):171-5. PubMed ID: 10764630
[TBL] [Abstract][Full Text] [Related]
15. Plasma pharmacokinetics and metabolism of 13-cis- and all-trans-retinoic acid in the cynomolgus monkey and the identification of 13-cis- and all-trans-retinoyl-beta-glucuronides. A comparison to one human case study with isotretinoin.
Kraft JC; Slikker W; Bailey JR; Roberts LG; Fischer B; Wittfoht W; Nau H
Drug Metab Dispos; 1991; 19(2):317-24. PubMed ID: 1676630
[TBL] [Abstract][Full Text] [Related]
16. Embryonic delivered dose of isotretinoin (13-cis-retinoic acid) and its metabolites in hamsters.
Eckhoff C; Willhite CC
Toxicol Appl Pharmacol; 1997 Sep; 146(1):79-87. PubMed ID: 9299599
[TBL] [Abstract][Full Text] [Related]
17. Physiologically based pharmacokinetics of methoxyacetic acid: dose-effect considerations in C57BL/6 mice.
O'Flaherty EJ; Nau H; McCandless D; Beliles RP; Schreiner CM; Scott WJ
Teratology; 1995 Aug; 52(2):78-89. PubMed ID: 8588185
[TBL] [Abstract][Full Text] [Related]
18. Clinical pharmacology of oral all-trans retinoic acid in patients with acute promyelocytic leukemia.
Muindi JR; Frankel SR; Huselton C; DeGrazia F; Garland WA; Young CW; Warrell RP
Cancer Res; 1992 Apr; 52(8):2138-42. PubMed ID: 1559217
[TBL] [Abstract][Full Text] [Related]
19. Placental transfer and developmental effects of 9-cis retinoic acid in mice.
Kochhar DM; Jiang H; Penner JD; Heyman RA
Teratology; 1995 Apr; 51(4):257-65. PubMed ID: 7570368
[TBL] [Abstract][Full Text] [Related]
20. Pharmacokinetic assessment of teratologically effective concentrations of an endogenous retinoic acid metabolite.
Satre MA; Penner JD; Kochhar DM
Teratology; 1989 Apr; 39(4):341-8. PubMed ID: 2749577
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
