193 related articles for article (PubMed ID: 9145912)
1. Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.
Schmiedlin-Ren P; Thummel KE; Fisher JM; Paine MF; Lown KS; Watkins PB
Mol Pharmacol; 1997 May; 51(5):741-54. PubMed ID: 9145912
[TBL] [Abstract][Full Text] [Related]
2. CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies.
Engman HA; Lennernäs H; Taipalensuu J; Otter C; Leidvik B; Artursson P
J Pharm Sci; 2001 Nov; 90(11):1736-51. PubMed ID: 11745731
[TBL] [Abstract][Full Text] [Related]
3. Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3.
Thummel KE; Brimer C; Yasuda K; Thottassery J; Senn T; Lin Y; Ishizuka H; Kharasch E; Schuetz J; Schuetz E
Mol Pharmacol; 2001 Dec; 60(6):1399-406. PubMed ID: 11723248
[TBL] [Abstract][Full Text] [Related]
4. Alteration of cellular phosphorylation state affects vitamin D receptor-mediated CYP3A4 mRNA induction in Caco-2 cells.
Hara H; Yasunami Y; Adachi T
Biochem Biophys Res Commun; 2002 Aug; 296(1):182-8. PubMed ID: 12147248
[TBL] [Abstract][Full Text] [Related]
5. Loss of CYP3A7 gene induction by 1,25-dihydroxyvitamin D3 is caused by less binding of VDR to the proximal ER6 in CYP3A7 gene.
Hara H; Yasunami Y; Adachi T
Biochem Biophys Res Commun; 2004 Sep; 321(4):909-15. PubMed ID: 15358113
[TBL] [Abstract][Full Text] [Related]
6. Induction of CYP3A4 by 1 alpha,25-dihydroxyvitamin D3 is human cell line-specific and is unlikely to involve pregnane X receptor.
Schmiedlin-Ren P; Thummel KE; Fisher JM; Paine MF; Watkins PB
Drug Metab Dispos; 2001 Nov; 29(11):1446-53. PubMed ID: 11602520
[TBL] [Abstract][Full Text] [Related]
7. First-pass midazolam metabolism catalyzed by 1alpha,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers.
Fisher JM; Wrighton SA; Watkins PB; Schmiedlin-Ren P; Calamia JC; Shen DD; Kunze KL; Thummel KE
J Pharmacol Exp Ther; 1999 May; 289(2):1134-42. PubMed ID: 10215697
[TBL] [Abstract][Full Text] [Related]
8. Inhibitory effect of nitric oxide on the induction of cytochrome P450 3A4 mRNA by 1,25-dihydroxyvitamin D3 in Caco-2 cells.
Hara H; Mitani N; Adachi T
Free Radic Res; 2000 Sep; 33(3):279-85. PubMed ID: 10993481
[TBL] [Abstract][Full Text] [Related]
9. Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1alpha,25-dihydroxyvitamin D(3): implications for drug-induced osteomalacia.
Xu Y; Hashizume T; Shuhart MC; Davis CL; Nelson WL; Sakaki T; Kalhorn TF; Watkins PB; Schuetz EG; Thummel KE
Mol Pharmacol; 2006 Jan; 69(1):56-65. PubMed ID: 16207822
[TBL] [Abstract][Full Text] [Related]
10. Role of c-Myc in nitric oxide-mediated suppression of cytochrome P450 3A4.
Watabe M; Isogai Y; Numazawa S; Yoshida T
Life Sci; 2003 Nov; 74(1):99-108. PubMed ID: 14575816
[TBL] [Abstract][Full Text] [Related]
11. Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein.
Brimer C; Dalton JT; Zhu Z; Schuetz J; Yasuda K; Vanin E; Relling MV; Lu Y; Schuetz EG
Pharm Res; 2000 Jul; 17(7):803-10. PubMed ID: 10990198
[TBL] [Abstract][Full Text] [Related]
12. CYP3A gene expression in human gut epithelium.
Kolars JC; Lown KS; Schmiedlin-Ren P; Ghosh M; Fang C; Wrighton SA; Merion RM; Watkins PB
Pharmacogenetics; 1994 Oct; 4(5):247-59. PubMed ID: 7894497
[TBL] [Abstract][Full Text] [Related]
13. Investigation of the coordinated functional activities of cytochrome P450 3A4 and P-glycoprotein in limiting the absorption of xenobiotics in Caco-2 cells.
Tran CD; Timmins P; Conway BR; Irwin WJ
J Pharm Sci; 2002 Jan; 91(1):117-28. PubMed ID: 11782903
[TBL] [Abstract][Full Text] [Related]
14. CYP3A4 is a human microsomal vitamin D 25-hydroxylase.
Gupta RP; Hollis BW; Patel SB; Patrick KS; Bell NH
J Bone Miner Res; 2004 Apr; 19(4):680-8. PubMed ID: 15005856
[TBL] [Abstract][Full Text] [Related]
15. C-jun N-terminal kinase modulates 1,25-dihydroxyvitamin D3-induced cytochrome P450 3A4 gene expression.
Yasunami Y; Hara H; Iwamura T; Kataoka T; Adachi T
Drug Metab Dispos; 2004 Jul; 32(7):685-8. PubMed ID: 15205382
[TBL] [Abstract][Full Text] [Related]
16. Induction of CYP3A4 by 1alpha,25-dyhydroxyvitamin D3 in HepG2 cells.
Elizondo G; Medina-Díaz IM
Life Sci; 2003 May; 73(2):141-9. PubMed ID: 12738030
[TBL] [Abstract][Full Text] [Related]
17. The effects of culture conditions on CYP3A4 and MDR1 mRNA induction by 1alpha,25-dihydroxyvitamin D(3) in human intestinal cell lines, Caco-2 and LS180.
Aiba T; Susa M; Fukumori S; Hashimoto Y
Drug Metab Pharmacokinet; 2005 Aug; 20(4):268-74. PubMed ID: 16141606
[TBL] [Abstract][Full Text] [Related]
18. Gene Expression Profiling of 1α,25(OH)
Pavek P; Dusek J; Smutny T; Lochman L; Kucera R; Skoda J; Smutna L; Kamaraj R; Soucek P; Vrzal R; Dvorak Z
Mol Nutr Food Res; 2022 May; 66(9):e2200070. PubMed ID: 35184385
[TBL] [Abstract][Full Text] [Related]
19. Selective inhibition of human cytochrome P450 3A4 by N-[2(R)-hydroxy-1(S)-indanyl]-5-[2(S)-(1, 1-dimethylethylaminocarbonyl)-4-[(furo[2, 3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethy lpentanamide and P-glycoprotein by valspodar in gene transfectant systems.
Kawahara I; Kato Y; Suzuki H; Achira M; Ito K; Crespi CL; Sugiyama Y
Drug Metab Dispos; 2000 Oct; 28(10):1238-43. PubMed ID: 10997946
[TBL] [Abstract][Full Text] [Related]
20. Transport and metabolic characterization of Caco-2 cells expressing CYP3A4 and CYP3A4 plus oxidoreductase.
Hu M; Li Y; Davitt CM; Huang SM; Thummel K; Penman BW; Crespi CL
Pharm Res; 1999 Sep; 16(9):1352-9. PubMed ID: 10496649
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
