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3. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines. van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718 [TBL] [Abstract][Full Text] [Related]
4. A method for the determination of total, free, and 5-fluorodeoxyuridylate-bound thymidylate synthase in cell extracts. Fernandes DJ; Cranford SK Anal Biochem; 1984 Nov; 142(2):378-85. PubMed ID: 6241433 [TBL] [Abstract][Full Text] [Related]
6. Variation in human thymidylate synthase is associated with resistance to 5-fluoro-2'-deoxyuridine. Davis ST; Berger SH Mol Pharmacol; 1993 May; 43(5):702-8. PubMed ID: 8502227 [TBL] [Abstract][Full Text] [Related]
7. Reduction of 5-fluorouracil (5-FU) gastrointestinal (GI) toxicity resulting from the protection of thymidylate synthase (TS) in GI tissue by repeated simultaneous administration of potassium oxonate (Oxo) in rats. Yoshisue K; Hironaga K; Yamaguchi S; Yamamoto A; Nagayama S; Kawaguchi Y Cancer Chemother Pharmacol; 2000; 46(1):51-6. PubMed ID: 10912578 [TBL] [Abstract][Full Text] [Related]
8. Effect of polyglutamylation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft. Radparvar S; Houghton PJ; Houghton JA Biochem Pharmacol; 1989 Jan; 38(2):335-42. PubMed ID: 2914018 [TBL] [Abstract][Full Text] [Related]
9. Functional effects of a naturally occurring amino acid substitution in human thymidylate synthase. Hughey CT; Barbour KW; Berger FG; Berger SH Mol Pharmacol; 1993 Aug; 44(2):316-23. PubMed ID: 8355668 [TBL] [Abstract][Full Text] [Related]
10. Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue. Johnston PG; Liang CM; Henry S; Chabner BA; Allegra CJ Cancer Res; 1991 Dec; 51(24):6668-76. PubMed ID: 1720706 [TBL] [Abstract][Full Text] [Related]
11. Isolation and functional effects of monoclonal antibodies binding to thymidylate synthase. Jastreboff MM; Todd MB; Malech HL; Bertino JR Biochemistry; 1985 Jan; 24(3):587-92. PubMed ID: 3994977 [TBL] [Abstract][Full Text] [Related]
12. Biphasic binding of 5-fluoro-2'-deoxyuridylate to human thymidylate synthase. Reilly RT; Barbour KW; Dunlap RB; Berger FG Mol Pharmacol; 1995 Jul; 48(1):72-9. PubMed ID: 7623777 [TBL] [Abstract][Full Text] [Related]
14. Inhibition of thymidylate synthase after administration of doxifluridine in a transplantable colon carcinoma in the rat. Berne M; Gustavsson B; Almersjö O; Spears P; Sundström E Cancer Invest; 1988; 6(4):377-83. PubMed ID: 2972339 [TBL] [Abstract][Full Text] [Related]
15. Nuclear expression of thymidylate synthase in colorectal cancer cell lines and clinical samples. Bissoon-Haqqani S; Moyana T; Jonker D; Maroun JA; Birnboim HC J Histochem Cytochem; 2006 Jan; 54(1):19-29. PubMed ID: 15956025 [TBL] [Abstract][Full Text] [Related]
16. Recent advances in the study of rTS proteins. rTS expression during growth and in response to thymidylate synthase inhibitors in human tumor cells. Dolnick BJ; Lu K; Yin MB; Rustum YM Adv Enzyme Regul; 1997; 37():95-109. PubMed ID: 9381988 [TBL] [Abstract][Full Text] [Related]
17. Thymidylate synthase-catalyzed, tetrahydrofolate-dependent self-inactivation by 5-FdUMP. Sobich J; Prokopowicz M; Maj P; Wilk P; Zieliński Z; Frączyk T; Rode W Arch Biochem Biophys; 2019 Oct; 674():108106. PubMed ID: 31520592 [TBL] [Abstract][Full Text] [Related]
18. Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells. Pestalozzi BC; McGinn CJ; Kinsella TJ; Drake JC; Glennon MC; Allegra CJ; Johnston PG Br J Cancer; 1995 Jun; 71(6):1151-7. PubMed ID: 7779704 [TBL] [Abstract][Full Text] [Related]
19. Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed. Peters GJ; van Triest B; Backus HH; Kuiper CM; van der Wilt CL; Pinedo HM Eur J Cancer; 2000 May; 36(7):916-24. PubMed ID: 10785598 [TBL] [Abstract][Full Text] [Related]
20. Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines. Johnston PG; Drake JC; Trepel J; Allegra CJ Cancer Res; 1992 Aug; 52(16):4306-12. PubMed ID: 1643628 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]