BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 9154110)

  • 1. Aniline mustard analogues of the DNA-intercalating agent amsacrine: DNA interaction and biological activity.
    Fan JY; Valu KK; Woodgate PD; Baguley BC; Denny WA
    Anticancer Drug Des; 1997 Apr; 12(3):181-203. PubMed ID: 9154110
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differences in sequence selectivity of DNA alkylation by isomeric intercalating aniline mustards.
    Prakash AS; Denny WA; Wakelin LP
    Chem Biol Interact; 1990; 76(2):241-8. PubMed ID: 2225231
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA-directed alkylating agents. 3. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the length of the linker chain.
    Valu KK; Gourdie TA; Boritzki TJ; Gravatt GL; Baguley BC; Wilson WR; Wakelin LP; Woodgate PD; Denny WA
    J Med Chem; 1990 Nov; 33(11):3014-9. PubMed ID: 2231599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
    McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
    Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard.
    Gourdie TA; Valu KK; Gravatt GL; Boritzki TJ; Baguley BC; Wakelin LP; Wilson WR; Woodgate PD; Denny WA
    J Med Chem; 1990 Apr; 33(4):1177-86. PubMed ID: 2319563
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA-directed alkylating ligands as potential antitumor agents: sequence specificity of alkylation by intercalating aniline mustards.
    Prakash AS; Denny WA; Gourdie TA; Valu KK; Woodgate PD; Wakelin LP
    Biochemistry; 1990 Oct; 29(42):9799-807. PubMed ID: 2271617
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
    Palmer BD; Wilson WR; Anderson RF; Boyd M; Denny WA
    J Med Chem; 1996 Jun; 39(13):2518-28. PubMed ID: 8691449
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA-Directed alkylating agents. 7. Synthesis, DNA interaction, and antitumor activity of bis(hydroxymethyl)- and bis(carbamate)-substituted pyrrolizines and imidazoles.
    Atwell GJ; Fan JY; Tan K; Denny WA
    J Med Chem; 1998 Nov; 41(24):4744-54. PubMed ID: 9822545
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bacterial mutagenicity studies of DNA-intercalating aniline mustards: an insight into the mode of action of a novel class of anti-tumour drugs.
    Ferguson LR; Gourdie TA; Valu KK; Denny WA
    Anticancer Drug Des; 1989 Oct; 4(3):209-19. PubMed ID: 2679621
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5,7-Disubstituted analogues of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA): DNA binding and patterns of cytotoxicity.
    Spicer JA; Finlay GJ; Baguley BC; Velea L; Graves DE; Denny WA
    Anticancer Drug Des; 1999 Feb; 14(1):37-45. PubMed ID: 10363026
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 'Minimal' DNA-intercalating agents as anti-tumour drugs: 2-styrylquinoline analogues of amsacrine.
    Denny WA; Atwell GJ; Baguley BC
    Anticancer Drug Des; 1987 Dec; 2(3):263-70. PubMed ID: 3449090
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mono- and dysfunctional nitrogen mustard analogues of the DNA minor groove binder pibenzimol. Synthesis, cytotoxicity and interaction with DNA.
    Smaill JB; Fan JY; Papa PV; O'Connor CJ; Denny WA
    Anticancer Drug Des; 1998 Apr; 13(3):221-42. PubMed ID: 9595035
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological activity of stable and potent antitumor agents, aniline nitrogen mustards linked to 9-anilinoacridines via a urea linkage.
    Kapuriya N; Kapuriya K; Zhang X; Chou TC; Kakadiya R; Wu YT; Tsai TH; Chen YT; Lee TC; Shah A; Naliapara Y; Su TL
    Bioorg Med Chem; 2008 May; 16(10):5413-23. PubMed ID: 18450456
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of DNA-targeted spatially separated bis(aniline mustards) as potential alkylating agents with enhanced DNA cross-linking capability.
    Gourdie TA; Prakash AS; Wakelin LP; Woodgate PD; Denny WA
    J Med Chem; 1991 Jan; 34(1):240-8. PubMed ID: 1992124
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, DNA binding and cytotoxicity of 1-[[omega-(9-acridinyl)amino]alkyl]carbonyl -3-(chloromethyl)-6-hydroxyindolines, a new class of DNA-targeted alkylating agents.
    Fan JY; Tercel M; Denny WA
    Anticancer Drug Des; 1997 Jun; 12(4):277-93. PubMed ID: 9199660
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation.
    Smaill JB; Fan JY; Denny WA
    Anticancer Drug Des; 1998 Dec; 13(8):857-80. PubMed ID: 10335264
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A molecular modeling study of B-DNA-intercalation complexes with amsacrine and related 9-anilino-acridines.
    Fischer G; Pindur U
    Pharmazie; 1999 Feb; 54(2):83-93. PubMed ID: 10084153
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinetic and equilibrium studies of the interaction of amsacrine and anilino ring-substituted analogues with DNA.
    Denny WA; Wakelin LP
    Cancer Res; 1986 Apr; 46(4 Pt 1):1717-21. PubMed ID: 3753896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA adducts of 9-anilinoacridine mustards: characterization by NMR.
    Fan JY; Ohms SJ; Boyd M; Denny WA
    Chem Res Toxicol; 1999 Dec; 12(12):1166-72. PubMed ID: 10604865
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytotoxic action and cell cycle effects of ALGA, a peptidic derivative of the antileukemic drug amsacrine.
    Collyn-d'Hooghe M; Bernier JL; Henichart JP
    Cancer Biochem Biophys; 1987 Sep; 9(3):257-64. PubMed ID: 3435897
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.