BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 9155531)

  • 21. Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.
    Kokkinakis DM; Ahmed MM; Delgado R; Fruitwala MM; Mohiuddin M; Albores-Saavedra J
    Cancer Res; 1997 Dec; 57(23):5360-8. PubMed ID: 9393761
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Selective and synergistic activity of L-S,R-buthionine sulfoximine on malignant melanoma is accompanied by decreased expression of glutathione-S-transferase.
    Fruehauf JP; Zonis S; al-Bassam M; Kyshtoobayeva A; Dasgupta C; Milovanovic T; Parker RJ; Buzaid AC
    Pigment Cell Res; 1997 Aug; 10(4):236-49. PubMed ID: 9263331
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Evidence for nucleotide excision repair as a modifying factor of O6-methylguanine-DNA methyltransferase-mediated innate chloroethylnitrosourea resistance in human tumor cell lines.
    Chen ZP; Malapetsa A; McQuillan A; Marcantonio D; Bello V; Mohr G; Remack J; Brent TP; Panasci LC
    Mol Pharmacol; 1997 Nov; 52(5):815-20. PubMed ID: 9351972
    [TBL] [Abstract][Full Text] [Related]  

  • 24. O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
    Hermisson M; Klumpp A; Wick W; Wischhusen J; Nagel G; Roos W; Kaina B; Weller M
    J Neurochem; 2006 Feb; 96(3):766-76. PubMed ID: 16405512
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The O6-methyguanine-DNA methyltransferase inhibitor O6-benzylguanine enhanced activity of temozolomide + irinotecan against models of high-risk neuroblastoma.
    Hindle A; Koneru B; Makena MR; Lopez-Barcons L; Chen WH; Nguyen TH; Reynolds CP
    Anticancer Drugs; 2021 Mar; 32(3):233-247. PubMed ID: 33323683
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Depletion of O6-methylguanine-DNA methyltransferase by O6-benzylguanine enhances 5-FU cytotoxicity in colon and oral cancer cell lines.
    Murakami J; Lee YJ; Kokeguchi S; Tsujigiwa H; Asaumi J; Nagatsuka H; Fukui K; Kuroda M; Tanaka N; Matsubara N
    Oncol Rep; 2007 Jun; 17(6):1461-7. PubMed ID: 17487405
    [TBL] [Abstract][Full Text] [Related]  

  • 27. O6-benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial rat glioma.
    Rhines LD; Sampath P; Dolan ME; Tyler BM; Brem H; Weingart J
    Cancer Res; 2000 Nov; 60(22):6307-10. PubMed ID: 11103789
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Characterization of the P140K, PVP(138-140)MLK, and G156A O6-methylguanine-DNA methyltransferase mutants: implications for drug resistance gene therapy.
    Davis BM; Roth JC; Liu L; Xu-Welliver M; Pegg AE; Gerson SL
    Hum Gene Ther; 1999 Nov; 10(17):2769-78. PubMed ID: 10584923
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Simultaneous protection of G156A methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and sensitization of tumor cells using O6-benzylguanine and temozolomide.
    Reese JS; Davis BM; Liu L; Gerson SL
    Clin Cancer Res; 1999 Jan; 5(1):163-9. PubMed ID: 9918215
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Potentiation of temozolomide and BCNU cytotoxicity by O(6)-benzylguanine: a comparative study in vitro.
    Wedge SR; Porteus JK; May BL; Newlands ES
    Br J Cancer; 1996 Feb; 73(4):482-90. PubMed ID: 8595163
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Modulation of O6-methylguanine-DNA methyltransferase-mediated 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea resistance by O6-benzylguanine in vitro and in vivo.
    Chen JM; Zhang YP; Sui JL; Moschel RC; Ikenaga M
    Anticancer Res; 1993; 13(3):801-5. PubMed ID: 8317915
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mechanisms of resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea in human medulloblastoma and rhabdomyosarcoma.
    Bacolod MD; Johnson SP; Ali-Osman F; Modrich P; Bullock NS; Colvin OM; Bigner DD; Friedman HS
    Mol Cancer Ther; 2002 Jul; 1(9):727-36. PubMed ID: 12479369
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Protection of CHO cells by mutant forms of O6-alkylguanine-DNA alkyltransferase from killing by 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) plus O6-benzylguanine or O6-benzyl-8-oxoguanine.
    Loktionova NA; Xu-Welliver M; Crone TM; Kanugula S; Pegg AE
    Biochem Pharmacol; 1999 Jul; 58(2):237-44. PubMed ID: 10423163
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
    Ali-Osman F; Antoun G; Wang H; Rajagopal S; Gagucas E
    Mol Pharmacol; 1996 Jun; 49(6):1012-20. PubMed ID: 8649339
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to O6-methylguanine DNA-methyltransferase expression.
    Passagne I; Evrard A; Winum JY; Depeille P; Cuq P; Montero JL; Cupissol D; Vian L
    J Pharmacol Exp Ther; 2003 Nov; 307(2):816-23. PubMed ID: 12970393
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Differential inactivation of O6-methylguanine-DNA methyltransferase activity by O6-arylmethylguanines.
    Mineura K; Fukuchi M; Kowada M; Terashima I; Kohda K
    Int J Cancer; 1995 Sep; 63(1):148-51. PubMed ID: 7558444
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Point mutations in human O6-alkylguanine-DNA alkyltransferase prevent the sensitization by O6-benzylguanine to killing by N,N'-bis (2-chloroethyl)-N-nitrosourea.
    Loktionova NA; Pegg AE
    Cancer Res; 1996 Apr; 56(7):1578-83. PubMed ID: 8603405
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Differential sensitivity of human and mouse alkyltransferase to O6-benzylguanine using a transgenic model.
    Liu L; Lee K; Wasan E; Gerson SL
    Cancer Res; 1996 Apr; 56(8):1880-5. PubMed ID: 8620508
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme.
    Friedman HS; Dolan ME; Moschel RC; Pegg AE; Felker GM; Rich J; Bigner DD; Schold SC
    J Natl Cancer Inst; 1992 Dec; 84(24):1926-31. PubMed ID: 1334154
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mitomycin C sensitivity in human bladder cancer cells: possible role of glutathione and glutathione transferase in resistance.
    Xu BH; Gupta V; Singh SV
    Arch Biochem Biophys; 1994 Jan; 308(1):164-70. PubMed ID: 8311448
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.