These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 9163334)

  • 1. Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides.
    Nery ED; Juliano MA; Meldal M; Svendsen I; Scharfstein J; Walmsley A; Juliano L
    Biochem J; 1997 Apr; 323 ( Pt 2)(Pt 2):427-33. PubMed ID: 9163334
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discrimination of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, and mammalian cathepsins B and L, by a pH-inducible fluorogenic substrate of trypanosomal cysteine proteinases.
    Serveau C; Lalmanach G; Hirata I; Scharfstein J; Juliano MA; Gauthier F
    Eur J Biochem; 1999 Jan; 259(1-2):275-80. PubMed ID: 9914503
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and hydrolysis by cysteine and serine proteases of short internally quenched fluorogenic peptides.
    Melo RL; Alves LC; Del Nery E; Juliano L; Juliano MA
    Anal Biochem; 2001 Jun; 293(1):71-7. PubMed ID: 11373081
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors.
    Serveau C; Lalmanach G; Juliano MA; Scharfstein J; Juliano L; Gauthier F
    Biochem J; 1996 Feb; 313 ( Pt 3)(Pt 3):951-6. PubMed ID: 8611180
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of cruzipain visualized in a fluorescence quenched solid-phase inhibitor library assay. D-amino acid inhibitors for cruzipain, cathepsin B and cathepsin L.
    Meldal M; Svendsen IB; Juliano L; Juliano MA; Nery ED; Scharfstein J
    J Pept Sci; 1998 Apr; 4(2):83-91. PubMed ID: 9620612
    [TBL] [Abstract][Full Text] [Related]  

  • 6. S1 subsite specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids.
    Alves LC; Melo RL; Sanderson SJ; Mottram JC; Coombs GH; Caliendo G; Santagada V; Juliano L; Juliano MA
    Eur J Biochem; 2001 Mar; 268(5):1206-12. PubMed ID: 11231271
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kininogenase activity by the major cysteinyl proteinase (cruzipain) from Trypanosoma cruzi.
    Del Nery E; Juliano MA; Lima AP; Scharfstein J; Juliano L
    J Biol Chem; 1997 Oct; 272(41):25713-8. PubMed ID: 9325296
    [TBL] [Abstract][Full Text] [Related]  

  • 8. S3 to S3' subsite specificity of recombinant human cathepsin K and development of selective internally quenched fluorescent substrates.
    Alves MF; Puzer L; Cotrin SS; Juliano MA; Juliano L; Brömme D; Carmona AK
    Biochem J; 2003 Aug; 373(Pt 3):981-6. PubMed ID: 12733990
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Substrate specificity of recombinant cysteine proteinase, CPB, of Leishmania mexicana.
    Alves LC; Judice WA; St Hilaire PM; Meldal M; Sanderson SJ; Mottram JC; Coombs GH; Juliano L; Juliano MA
    Mol Biochem Parasitol; 2001 Aug; 116(1):1-9. PubMed ID: 11463460
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of the specificity, stability and individual rate constants with respective activation parameters for the peptidase activity of cruzipain and its recombinant form, cruzain, from Trypanosoma cruzi.
    Judice WA; Cezari MH; Lima AP; Scharfstein J; Chagas JR; Tersariol IL; Juliano MA; Juliano L
    Eur J Biochem; 2001 Dec; 268(24):6578-86. PubMed ID: 11737212
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Probing the specificity of cysteine proteinases at subsites remote from the active site: analysis of P4, P3, P2' and P3' variations in extended substrates.
    Portaro FC; Santos AB; Cezari MH; Juliano MA; Juliano L; Carmona E
    Biochem J; 2000 Apr; 347 Pt 1(Pt 1):123-9. PubMed ID: 10727410
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular modeling and substrate specificity of discrete cruzipain-like and cathepsin L-like cysteine proteinases of the human blood fluke Schistosoma mansoni.
    Brady CP; Brinkworth RI; Dalton JP; Dowd AJ; Verity CK; Brindley PJ
    Arch Biochem Biophys; 2000 Aug; 380(1):46-55. PubMed ID: 10900131
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Subsite specificity (S3, S2, S1', S2' and S3') of oligopeptidase B from Trypanosoma cruzi and Trypanosoma brucei using fluorescent quenched peptides: comparative study and identification of specific carboxypeptidase activity.
    Hemerly JP; Oliveira V; Del Nery E; Morty RE; Andrews NW; Juliano MA; Juliano L
    Biochem J; 2003 Aug; 373(Pt 3):933-9. PubMed ID: 12737623
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitors of the major cysteinyl proteinase (GP57/51) impair host cell invasion and arrest the intracellular development of Trypanosoma cruzi in vitro.
    Meirelles MN; Juliano L; Carmona E; Silva SG; Costa EM; Murta AC; Scharfstein J
    Mol Biochem Parasitol; 1992 Jun; 52(2):175-84. PubMed ID: 1620157
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biotin-labelled peptidyl diazomethane inhibitors derived from the substrate-like sequence of cystatin: targeting of the active site of cruzipain, the major cysteine proteinase of Trypanosoma cruzi.
    Lalmanach G; Mayer R; Serveau C; Scharfstein J; Gauthier F
    Biochem J; 1996 Sep; 318 ( Pt 2)(Pt 2):395-9. PubMed ID: 8809025
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of the S(2) subsite specificities of the recombinant cysteine proteinases CPB of Leishmania mexicana, and cruzain of Trypanosoma cruzi, using fluorescent substrates containing non-natural basic amino acids.
    Alves LC; Melo RL; Cezari MH; Sanderson SJ; Mottram JC; Coombs GH; Juliano L; Juliano MA
    Mol Biochem Parasitol; 2001 Oct; 117(2):137-43. PubMed ID: 11606223
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Specificity of cathepsin B to fluorescent substrates containing benzyl side-chain-substituted amino acids at P1 subsite.
    Del Nery E; Alves LC; Melo RL; Cesari MH; Juliano L; Juliano MA
    J Protein Chem; 2000 Jan; 19(1):33-8. PubMed ID: 10882170
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The substrate specificity of a recombinant cysteine protease from Leishmania mexicana: application of a combinatorial peptide library approach.
    St Hilaire PM; Alves LC; Sanderson SJ; Mottram JC; Juliano MA; Juliano L; Coombs GH; Meldal M
    Chembiochem; 2000 Aug; 1(2):115-22. PubMed ID: 11828405
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative substrate specificity analysis of recombinant human cathepsin V and cathepsin L.
    Puzer L; Cotrin SS; Alves MF; Egborge T; Araújo MS; Juliano MA; Juliano L; Brömme D; Carmona AK
    Arch Biochem Biophys; 2004 Oct; 430(2):274-83. PubMed ID: 15369827
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors.
    Lima AP; dos Reis FC; Serveau C; Lalmanach G; Juliano L; Ménard R; Vernet T; Thomas DY; Storer AC; Scharfstein J
    Mol Biochem Parasitol; 2001 Apr; 114(1):41-52. PubMed ID: 11356512
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.