164 related articles for article (PubMed ID: 9163334)
1. Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides.
Nery ED; Juliano MA; Meldal M; Svendsen I; Scharfstein J; Walmsley A; Juliano L
Biochem J; 1997 Apr; 323 ( Pt 2)(Pt 2):427-33. PubMed ID: 9163334
[TBL] [Abstract][Full Text] [Related]
2. Discrimination of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, and mammalian cathepsins B and L, by a pH-inducible fluorogenic substrate of trypanosomal cysteine proteinases.
Serveau C; Lalmanach G; Hirata I; Scharfstein J; Juliano MA; Gauthier F
Eur J Biochem; 1999 Jan; 259(1-2):275-80. PubMed ID: 9914503
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and hydrolysis by cysteine and serine proteases of short internally quenched fluorogenic peptides.
Melo RL; Alves LC; Del Nery E; Juliano L; Juliano MA
Anal Biochem; 2001 Jun; 293(1):71-7. PubMed ID: 11373081
[TBL] [Abstract][Full Text] [Related]
4. Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors.
Serveau C; Lalmanach G; Juliano MA; Scharfstein J; Juliano L; Gauthier F
Biochem J; 1996 Feb; 313 ( Pt 3)(Pt 3):951-6. PubMed ID: 8611180
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of cruzipain visualized in a fluorescence quenched solid-phase inhibitor library assay. D-amino acid inhibitors for cruzipain, cathepsin B and cathepsin L.
Meldal M; Svendsen IB; Juliano L; Juliano MA; Nery ED; Scharfstein J
J Pept Sci; 1998 Apr; 4(2):83-91. PubMed ID: 9620612
[TBL] [Abstract][Full Text] [Related]
6. S1 subsite specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids.
Alves LC; Melo RL; Sanderson SJ; Mottram JC; Coombs GH; Caliendo G; Santagada V; Juliano L; Juliano MA
Eur J Biochem; 2001 Mar; 268(5):1206-12. PubMed ID: 11231271
[TBL] [Abstract][Full Text] [Related]
7. Kininogenase activity by the major cysteinyl proteinase (cruzipain) from Trypanosoma cruzi.
Del Nery E; Juliano MA; Lima AP; Scharfstein J; Juliano L
J Biol Chem; 1997 Oct; 272(41):25713-8. PubMed ID: 9325296
[TBL] [Abstract][Full Text] [Related]
8. Substrate specificity of recombinant cysteine proteinase, CPB, of Leishmania mexicana.
Alves LC; Judice WA; St Hilaire PM; Meldal M; Sanderson SJ; Mottram JC; Coombs GH; Juliano L; Juliano MA
Mol Biochem Parasitol; 2001 Aug; 116(1):1-9. PubMed ID: 11463460
[TBL] [Abstract][Full Text] [Related]
9. Probing the specificity of cysteine proteinases at subsites remote from the active site: analysis of P4, P3, P2' and P3' variations in extended substrates.
Portaro FC; Santos AB; Cezari MH; Juliano MA; Juliano L; Carmona E
Biochem J; 2000 Apr; 347 Pt 1(Pt 1):123-9. PubMed ID: 10727410
[TBL] [Abstract][Full Text] [Related]
10. Molecular modeling and substrate specificity of discrete cruzipain-like and cathepsin L-like cysteine proteinases of the human blood fluke Schistosoma mansoni.
Brady CP; Brinkworth RI; Dalton JP; Dowd AJ; Verity CK; Brindley PJ
Arch Biochem Biophys; 2000 Aug; 380(1):46-55. PubMed ID: 10900131
[TBL] [Abstract][Full Text] [Related]
11. Inhibitors of the major cysteinyl proteinase (GP57/51) impair host cell invasion and arrest the intracellular development of Trypanosoma cruzi in vitro.
Meirelles MN; Juliano L; Carmona E; Silva SG; Costa EM; Murta AC; Scharfstein J
Mol Biochem Parasitol; 1992 Jun; 52(2):175-84. PubMed ID: 1620157
[TBL] [Abstract][Full Text] [Related]
12. Biotin-labelled peptidyl diazomethane inhibitors derived from the substrate-like sequence of cystatin: targeting of the active site of cruzipain, the major cysteine proteinase of Trypanosoma cruzi.
Lalmanach G; Mayer R; Serveau C; Scharfstein J; Gauthier F
Biochem J; 1996 Sep; 318 ( Pt 2)(Pt 2):395-9. PubMed ID: 8809025
[TBL] [Abstract][Full Text] [Related]
13. Analysis of the S(2) subsite specificities of the recombinant cysteine proteinases CPB of Leishmania mexicana, and cruzain of Trypanosoma cruzi, using fluorescent substrates containing non-natural basic amino acids.
Alves LC; Melo RL; Cezari MH; Sanderson SJ; Mottram JC; Coombs GH; Juliano L; Juliano MA
Mol Biochem Parasitol; 2001 Oct; 117(2):137-43. PubMed ID: 11606223
[TBL] [Abstract][Full Text] [Related]
14. Specificity of cathepsin B to fluorescent substrates containing benzyl side-chain-substituted amino acids at P1 subsite.
Del Nery E; Alves LC; Melo RL; Cesari MH; Juliano L; Juliano MA
J Protein Chem; 2000 Jan; 19(1):33-8. PubMed ID: 10882170
[TBL] [Abstract][Full Text] [Related]
15. Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors.
Lima AP; dos Reis FC; Serveau C; Lalmanach G; Juliano L; Ménard R; Vernet T; Thomas DY; Storer AC; Scharfstein J
Mol Biochem Parasitol; 2001 Apr; 114(1):41-52. PubMed ID: 11356512
[TBL] [Abstract][Full Text] [Related]
16. Subsite specificity of trypanosomal cathepsin L-like cysteine proteases. Probing the S2 pocket with phenylalanine-derived amino acids.
Lecaille F; Authié E; Moreau T; Serveau C; Gauthier F; Lalmanach G
Eur J Biochem; 2001 May; 268(9):2733-41. PubMed ID: 11322895
[TBL] [Abstract][Full Text] [Related]
17. The specificity of clostripain from Clostridium histolyticum. Mapping the S' subsites via acyl transfer to amino acid amides and peptides.
Ullmann D; Jakubke HD
Eur J Biochem; 1994 Aug; 223(3):865-72. PubMed ID: 8055964
[TBL] [Abstract][Full Text] [Related]
18. A comparison of the enzymatic properties of the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi.
Chagas JR; Authie E; Serveau C; Lalmanach G; Juliano L; Gauthier F
Mol Biochem Parasitol; 1997 Sep; 88(1-2):85-94. PubMed ID: 9274870
[TBL] [Abstract][Full Text] [Related]
19. Peptidyl substrates containing unnatural amino acid at the P'1 position are potent inhibitors of prohormone convertases.
Basak A; Schmidt C; Ismail AA; Seidah NG; Chrétien M; Lazure C
Int J Pept Protein Res; 1995; 46(3-4):228-37. PubMed ID: 8537176
[TBL] [Abstract][Full Text] [Related]
20. Chromogenic and fluorogenic glycosylated and acetylglycosylated peptides as substrates for serine, thiol and aspartyl proteases.
Juliano MA; Filira F; Gobbo M; Rocchi R; Del Nery E; Juliano L
J Pept Res; 1999 Feb; 53(2):109-19. PubMed ID: 10195448
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
