BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 9163700)

  • 1. Metabolic activation of aromatic amines by human pancreas.
    Anderson KE; Hammons GJ; Kadlubar FF; Potter JD; Kaderlik KR; Ilett KF; Minchin RF; Teitel CH; Chou HC; Martin MV; Guengerich FP; Barone GW; Lang NP; Peterson LA
    Carcinogenesis; 1997 May; 18(5):1085-92. PubMed ID: 9163700
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation.
    Culp SJ; Roberts DW; Talaska G; Lang NP; Fu PP; Lay JO; Teitel CH; Snawder JE; Von Tungeln LS; Kadlubar FF
    Mutat Res; 1997 Aug; 378(1-2):97-112. PubMed ID: 9288889
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
    Patten CJ; Smith TJ; Murphy SE; Wang MH; Lee J; Tynes RE; Koch P; Yang CS
    Arch Biochem Biophys; 1996 Sep; 333(1):127-38. PubMed ID: 8806763
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolic activation and carcinogen-DNA adduct detection in human larynx.
    Degawa M; Stern SJ; Martin MV; Guengerich FP; Fu PP; Ilett KF; Kaderlik RK; Kadlubar FF
    Cancer Res; 1994 Sep; 54(18):4915-9. PubMed ID: 8069857
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
    Turesky RJ; Lang NP; Butler MA; Teitel CH; Kadlubar FF
    Carcinogenesis; 1991 Oct; 12(10):1839-45. PubMed ID: 1934265
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
    Yamazaki H; Inui Y; Yun CH; Guengerich FP; Shimada T
    Carcinogenesis; 1992 Oct; 13(10):1789-94. PubMed ID: 1423839
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
    Smith TJ; Guo Z; Gonzalez FJ; Guengerich FP; Stoner GD; Yang CS
    Cancer Res; 1992 Apr; 52(7):1757-63. PubMed ID: 1312898
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.
    Arlt VM; Stiborova M; Hewer A; Schmeiser HH; Phillips DH
    Cancer Res; 2003 Jun; 63(11):2752-61. PubMed ID: 12782579
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
    Smith TJ; Stoner GD; Yang CS
    Cancer Res; 1995 Dec; 55(23):5566-73. PubMed ID: 7585636
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
    Smith TJ; Liao AM; Liu Y; Jones AB; Anderson LM; Yang CS
    Carcinogenesis; 1997 Aug; 18(8):1577-84. PubMed ID: 9276633
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
    Patten CJ; Smith TJ; Friesen MJ; Tynes RE; Yang CS; Murphy SE
    Carcinogenesis; 1997 Aug; 18(8):1623-30. PubMed ID: 9276639
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The tobacco carcinogen NNK is stereoselectively reduced by human pancreatic microsomes and cytosols.
    Trushin N; Leder G; El-Bayoumy K; Hoffmann D; Beger HG; Henne-Bruns D; Ramadani M; Prokopczyk B
    Langenbecks Arch Surg; 2008 Jul; 393(4):571-9. PubMed ID: 18259773
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acetylator genotype-dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: relationship to arylamine N-acetyltransferase.
    Hein DW; Flammang TJ; Kirlin WG; Trinidad A; Ogolla F
    Carcinogenesis; 1987 Dec; 8(12):1767-74. PubMed ID: 3677303
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitory monoclonal antibodies to human cytochrome P450 1A2: analysis of phenacetin O-deethylation in human liver.
    Yang TJ; Sai Y; Krausz KW; Gonzalez FJ; Gelboin HV
    Pharmacogenetics; 1998 Oct; 8(5):375-82. PubMed ID: 9825829
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.
    Hein DW; Doll MA; Gray K; Rustan TD; Ferguson RJ
    Cancer Res; 1993 Feb; 53(3):509-14. PubMed ID: 8425184
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder.
    Badawi AF; Hirvonen A; Bell DA; Lang NP; Kadlubar FF
    Cancer Res; 1995 Nov; 55(22):5230-7. PubMed ID: 7585581
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanisms of cytochrome P450 1A2-mediated formation of N-hydroxy arylamines and heterocyclic amines and their reaction with guanyl residues.
    Guengerich FP; Humphreys WG; Yun CH; Hammons GJ; Kadlubar FF; Seto Y; Okazaki O; Martin MV
    Princess Takamatsu Symp; 1995; 23():78-84. PubMed ID: 8844798
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and N'- nitrosonornicotine in human hepatic microsomes.
    Staretz ME; Murphy SE; Patten CJ; Nunes MG; Koehl W; Amin S; Koenig LA; Guengerich FP; Hecht SS
    Drug Metab Dispos; 1997 Feb; 25(2):154-62. PubMed ID: 9029045
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Acetyl coenzyme A-dependent metabolic activation of N-hydroxy-3,2'-dimethyl-4-aminobiphenyl and several carcinogenic N-hydroxy arylamines in relation to tissue and species differences, other acyl donors, and arylhydroxamic acid-dependent acyltransferases.
    Flammang TJ; Kadlubar FF
    Carcinogenesis; 1986 Jun; 7(6):919-26. PubMed ID: 3708755
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13.
    Jalas JR; Ding X; Murphy SE
    Drug Metab Dispos; 2003 Oct; 31(10):1199-202. PubMed ID: 12975327
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.