141 related articles for article (PubMed ID: 9164418)
1. The effect of sorivudine on dihydropyrimidine dehydrogenase activity in patients with acute herpes zoster.
Yan J; Tyring SK; McCrary MM; Lee PC; Haworth S; Raymond R; Olsen SJ; Diasio RB
Clin Pharmacol Ther; 1997 May; 61(5):563-73. PubMed ID: 9164418
[TBL] [Abstract][Full Text] [Related]
2. A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
Okuda H; Ogura K; Kato A; Takubo H; Watabe T
J Pharmacol Exp Ther; 1998 Nov; 287(2):791-9. PubMed ID: 9808711
[TBL] [Abstract][Full Text] [Related]
3. [Molecular toxicological mechanism of the lethal interactions of the new antiviral drug, sorivudine, with 5-fluorouracil prodrugs and genetic deficiency of dihydropyrimidine dehydrogenase].
Watabe T; Ogura K; Nishiyama T
Yakugaku Zasshi; 2002 Aug; 122(8):527-35. PubMed ID: 12187768
[TBL] [Abstract][Full Text] [Related]
4. Lethal drug interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
Okuda H; Nishiyama T; Ogura K; Nagayama S; Ikeda K; Yamaguchi S; Nakamura Y; Kawaguchi K; Watabe T; Ogura Y
Drug Metab Dispos; 1997 Feb; 25(2):270-3. PubMed ID: 9029059
[TBL] [Abstract][Full Text] [Related]
5. Prediction of in vivo drug-drug interactions based on mechanism-based inhibition from in vitro data: inhibition of 5-fluorouracil metabolism by (E)-5-(2-Bromovinyl)uracil.
Kanamitsu SI; Ito K; Okuda H; Ogura K; Watabe T; Muro K; Sugiyama Y
Drug Metab Dispos; 2000 Apr; 28(4):467-74. PubMed ID: 10725316
[TBL] [Abstract][Full Text] [Related]
6. Impact of two weekly schedules of oral eniluracil given with fluorouracil and leucovorin on the duration of dihydropyrimidine dehydrogenase inhibition.
Keith B; Guo XD; Zentko S; Harold N; Schuler B; Quinn M; Shapiro J; Grem JL
Clin Cancer Res; 2002 May; 8(5):1045-50. PubMed ID: 12006517
[TBL] [Abstract][Full Text] [Related]
7. Intestinal anaerobic bacteria hydrolyse sorivudine, producing the high blood concentration of 5-(E)-(2-bromovinyl)uracil that increases the level and toxicity of 5-fluorouracil.
Nakayama H; Kinouchi T; Kataoka K; Akimoto S; Matsuda Y; Ohnishi Y
Pharmacogenetics; 1997 Feb; 7(1):35-43. PubMed ID: 9110360
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of dihydropyrimidine dehydrogenase by 5-propynyluracil, a metabolite of the anti-varicella zoster virus agent netivudine.
Peck R; Wiggs R; Callaghan J; Wootton R; Crome P; Fraser I; Frick L; Posner J
Clin Pharmacol Ther; 1996 Jan; 59(1):22-31. PubMed ID: 8549030
[TBL] [Abstract][Full Text] [Related]
9. Suicidal inactivation of human dihydropyrimidine dehydrogenase by (E)-5-(2-bromovinyl)uracil derived from the antiviral, sorivudine.
Ogura K; Nishiyama T; Takubo H; Kato A; Okuda H; Arakawa K; Fukushima M; Nagayama S; Kawaguchi Y; Watabe T
Cancer Lett; 1998 Jan; 122(1-2):107-13. PubMed ID: 9464498
[TBL] [Abstract][Full Text] [Related]
10. [Lethal drug interactions of the new antiviral, sorivudine, with anticancer prodrugs of 5-fluorouracil].
Watabe T; Okuda H; Ogura K
Yakugaku Zasshi; 1997 Nov; 117(10-11):910-21. PubMed ID: 9414600
[TBL] [Abstract][Full Text] [Related]
11. The uracil breath test in the assessment of dihydropyrimidine dehydrogenase activity: pharmacokinetic relationship between expired 13CO2 and plasma [2-13C]dihydrouracil.
Mattison LK; Fourie J; Hirao Y; Koga T; Desmond RA; King JR; Shimizu T; Diasio RB
Clin Cancer Res; 2006 Jan; 12(2):549-55. PubMed ID: 16428499
[TBL] [Abstract][Full Text] [Related]
12. Relationships among plasma [2-(13)C]uracil concentrations, breath (13)CO(2) expiration, and dihydropyrimidine dehydrogenase (DPD) activity in the liver in normal and dpd-deficient dogs.
Inada M; Hirao Y; Koga T; Itose M; Kunizaki J; Shimizu T; Sato H
Drug Metab Dispos; 2005 Mar; 33(3):381-7. PubMed ID: 15616154
[TBL] [Abstract][Full Text] [Related]
13. Mechanism-based inactivation of human dihydropyrimidine dehydrogenase by (E)-5-(2-bromovinyl)uracil in the presence of NADPH.
Nishiyama T; Ogura K; Okuda H; Suda K; Kato A; Watabe T
Mol Pharmacol; 2000 May; 57(5):899-905. PubMed ID: 10779372
[TBL] [Abstract][Full Text] [Related]
14. Dihydropyrimidine dehydrogenase (DPD) rapidly regenerates after inactivation by eniluracil (GW776C85) in primary and metastatic colorectal cancer.
Heslin MJ; Yan J; Weiss H; Shao L; Owens J; Lucas VS; Diasio RB
Cancer Chemother Pharmacol; 2003 Nov; 52(5):399-404. PubMed ID: 12904894
[TBL] [Abstract][Full Text] [Related]
15. Lethal drug interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
Okuda H; Nishiyama T; Ogura K; Nagayama S; Ikeda K; Yamaguchi S; Nakamura Y; Kawaguchi Y; Watabe T
Drug Metab Dispos; 1997 May; 25(5):270-3. PubMed ID: 9152608
[TBL] [Abstract][Full Text] [Related]
16. Sorivudine versus acyclovir for treatment of dermatomal herpes zoster in human immunodeficiency virus-infected patients: results from a randomized, controlled clinical trial. Collaborative Antiviral Study Group/AIDS Clinical Trials Group, Herpes Zoster Study Group.
Gnann JW; Crumpacker CS; Lalezari JP; Smith JA; Tyring SK; Baum KF; Borucki MJ; Joseph WP; Mertz GJ; Steigbigel RT; Cloud GA; Soong SJ; Sherrill LC; DeHertogh DA; Whitley RJ
Antimicrob Agents Chemother; 1998 May; 42(5):1139-45. PubMed ID: 9593141
[TBL] [Abstract][Full Text] [Related]
17. Sorivudine and 5-fluorouracil; a clinically significant drug-drug interaction due to inhibition of dihydropyrimidine dehydrogenase.
Diasio RB
Br J Clin Pharmacol; 1998 Jul; 46(1):1-4. PubMed ID: 9690942
[TBL] [Abstract][Full Text] [Related]
18. Dihydropyrimidine dehydrogenase activity during long-term adjuvant treatment with oral uracil and tegafur for colorectal cancer.
Sadahiro S; Suzuki T; Maeda Y; Ishikawa K; Tanaka Y; Yasuda S; Kamijo A; Makuuchi H; Murayama C
Chemotherapy; 2007; 53(6):442-5. PubMed ID: 17952005
[TBL] [Abstract][Full Text] [Related]
19. Sorivudine: a promising drug for the treatment of varicella-zoster virus infection.
Whitley RJ
Neurology; 1995 Dec; 45(12 Suppl 8):S73-5. PubMed ID: 8545030
[TBL] [Abstract][Full Text] [Related]
20. Plasma level of a 5-fluorouracil metabolite, fluoro-beta-alanine correlates with dihydropyrimidine dehydrogenase activity of peripheral blood mononuclear cells in 5-fluorouracil treated patients.
Furuhata T; Kawakami M; Okita K; Kimura Y; Kihara C; Tsuruma T; Ohmura T; Yamaguchi K; Hata F; Katsuramaki T; Sasaki K; Hirata K
J Exp Clin Cancer Res; 2006 Mar; 25(1):79-82. PubMed ID: 16761622
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
