BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 9168254)

  • 1. Pyridyloxobutyl adduct O6-[4-oxo-4-(3-pyridyl)butyl]guanine is present in 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-treated DNA and is a substrate for O6-alkylguanine-DNA alkyltransferase.
    Wang L; Spratt TE; Liu XK; Hecht SS; Pegg AE; Peterson LA
    Chem Res Toxicol; 1997 May; 10(5):562-7. PubMed ID: 9168254
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
    Thomson NM; Kenney PM; Peterson LA
    Chem Res Toxicol; 2003 Jan; 16(1):1-6. PubMed ID: 12693024
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pyridyloxobutylation of guanine residues by 4-[(acetoxymethyl)nitrosamino]-1-(3-pyridyl)-1-butanone generates substrates of O6-alkylguanine-DNA alkyltransferase.
    Liu XK; Spratt TE; Murphy SE; Peterson LA
    Chem Res Toxicol; 1996 Sep; 9(6):949-53. PubMed ID: 8870981
    [TBL] [Abstract][Full Text] [Related]  

  • 4. O6-pyridyloxobutylguanine adducts contribute to the mutagenic properties of pyridyloxobutylating agents.
    Mijal RS; Loktionova NA; Vu CC; Pegg AE; Peterson LA
    Chem Res Toxicol; 2005 Oct; 18(10):1619-25. PubMed ID: 16533027
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pyridyloxobutyl DNA adducts inhibit the repair of O6-methylguanine.
    Peterson LA; Liu XK; Hecht SS
    Cancer Res; 1993 Jun; 53(12):2780-5. PubMed ID: 8504419
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of DNA oligonucleotides containing site-specifically incorporated O6-[4-oxo-4-(3-pyridyl)butyl]guanine and their reaction with O6-alkylguanine-DNA alkyltransferase.
    Wang L; Spratt TE; Pegg AE; Peterson LA
    Chem Res Toxicol; 1999 Feb; 12(2):127-31. PubMed ID: 10027788
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of a quantitative liquid chromatography/electrospray mass spectrometric assay for a mutagenic tobacco specific nitrosamine-derived DNA adduct, O6-[4-Oxo-4-(3-pyridyl)butyl]-2'-deoxyguanosine.
    Thomson NM; Mijal RS; Ziegel R; Fleischer NL; Pegg AE; Tretyakova NY; Peterson LA
    Chem Res Toxicol; 2004 Dec; 17(12):1600-6. PubMed ID: 15606135
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The repair of the tobacco specific nitrosamine derived adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by O6-alkylguanine-DNA alkyltransferase variants.
    Mijal RS; Thomson NM; Fleischer NL; Pauly GT; Moschel RC; Kanugula S; Fang Q; Pegg AE; Peterson LA
    Chem Res Toxicol; 2004 Mar; 17(3):424-34. PubMed ID: 15025514
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA sequence context affects repair of the tobacco-specific adduct O(6)-[4-Oxo-4-(3-pyridyl)butyl]guanine by human O(6)-alkylguanine-DNA alkyltransferases.
    Mijal RS; Kanugula S; Vu CC; Fang Q; Pegg AE; Peterson LA
    Cancer Res; 2006 May; 66(9):4968-74. PubMed ID: 16651455
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of O2-substituted pyrimidine adducts formed in reactions of 4-(acetoxymethylnitrosamino)- 1-(3-pyridyl)-1-butanone and 4-(acetoxymethylnitros- amino)-1-(3-pyridyl)-1-butanol with DNA.
    Hecht SS; Villalta PW; Sturla SJ; Cheng G; Yu N; Upadhyaya P; Wang M
    Chem Res Toxicol; 2004 May; 17(5):588-97. PubMed ID: 15144215
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone, a chemically activated form of tobacco specific carcinogens.
    Wang M; Cheng G; Sturla SJ; Shi Y; McIntee EJ; Villalta PW; Upadhyaya P; Hecht SS
    Chem Res Toxicol; 2003 May; 16(5):616-26. PubMed ID: 12755591
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Formation and repair of pyridyloxobutyl DNA adducts and their relationship to tumor yield in A/J mice.
    Urban AM; Upadhyaya P; Cao Q; Peterson LA
    Chem Res Toxicol; 2012 Oct; 25(10):2167-78. PubMed ID: 22928598
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quantitation of pyridyloxobutyl DNA adducts of tobacco-specific nitrosamines in rat tissue DNA by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
    Lao Y; Villalta PW; Sturla SJ; Wang M; Hecht SS
    Chem Res Toxicol; 2006 May; 19(5):674-82. PubMed ID: 16696570
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparison of the rates of repair of O6-alkylguanines in DNA by rat liver and bacterial O6-alkylguanine-DNA alkyltransferase.
    Pegg AE; Scicchitano D; Dolan ME
    Cancer Res; 1984 Sep; 44(9):3806-11. PubMed ID: 6378375
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel, sensitive assay for O6-methyl- and O6-ethylguanine in DNA, based on repair by the enzyme O6-alkylguanine-DNA-alkyltransferase in competition with an oligonucleotide containing O6-methylguanine.
    Souliotis VL; Kyrtopoulos SA
    Cancer Res; 1989 Dec; 49(24 Pt 1):6997-7001. PubMed ID: 2684406
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specific labeling of O6-alkylguanine-DNA alkyltransferase by reaction with O6-(p-hydroxy[3H]methylbenzyl)guanine.
    Ciocco GM; Moschel RC; Chae MY; McLaughlin PJ; Zagon IS; Pegg AE
    Cancer Res; 1995 Sep; 55(18):4085-91. PubMed ID: 7664284
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of adducts produced by the reaction of 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanol with deoxyguanosine and DNA.
    Upadhyaya P; Sturla SJ; Tretyakova N; Ziegel R; Villalta PW; Wang M; Hecht SS
    Chem Res Toxicol; 2003 Feb; 16(2):180-90. PubMed ID: 12588189
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interactions between methylating and pyridyloxobutylating agents in A/J mouse lungs: implications for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.
    Peterson LA; Thomson NM; Crankshaw DL; Donaldson EE; Kenney PJ
    Cancer Res; 2001 Aug; 61(15):5757-63. PubMed ID: 11479212
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reduction of O6-alkylguanine-DNA alkyltransferase activity in HeLa cells treated with O6-alkylguanines.
    Dolan ME; Morimoto K; Pegg AE
    Cancer Res; 1985 Dec; 45(12 Pt 1):6413-7. PubMed ID: 4063990
    [TBL] [Abstract][Full Text] [Related]  

  • 20. O6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung.
    Peterson LA; Hecht SS
    Cancer Res; 1991 Oct; 51(20):5557-64. PubMed ID: 1913675
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.