BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 9168257)

  • 21. Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxification pathway catalyzed by cytochrome P450 1A2.
    Langouët S; Welti DH; Kerriguy N; Fay LB; Huynh-Ba T; Markovic J; Guengerich FP; Guillouzo A; Turesky RJ
    Chem Res Toxicol; 2001 Feb; 14(2):211-21. PubMed ID: 11258970
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Genotoxic activity of the N-acetylated metabolites of the food mutagens 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ).
    Brunborg G; Holme JA; Alexander J; Becher G; Hongslo JK
    Mutagenesis; 1988 Jul; 3(4):303-9. PubMed ID: 3062317
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Antimutagenic effects and possible mechanisms of action of vitamins and related compounds against genotoxic heterocyclic amines from cooked food.
    Edenharder R; Worf-Wandelburg A; Decker M; Platt KL
    Mutat Res; 1999 Jul; 444(1):235-48. PubMed ID: 10477359
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Prostaglandin-H synthase mediated metabolism and mutagenic activation of 2-amino-3-methylimidazo [4,5-f] quinoline (IQ).
    Wolz E; Wild D; Degen GH
    Arch Toxicol; 1995; 69(3):171-9. PubMed ID: 7717873
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.
    Duarte MP; Palma BB; Gilep AA; Laires A; Oliveira JS; Usanov SA; Rueff J; Kranendonk M
    Mutagenesis; 2005 Mar; 20(2):93-100. PubMed ID: 15728263
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Establishment of a Salmonella tester strain highly sensitive to mutagenic heterocyclic amines.
    Suzuki A; Kushida H; Iwata H; Watanabe M; Nohmi T; Fujita K; Gonzalez FJ; Kamataki T
    Cancer Res; 1998 May; 58(9):1833-8. PubMed ID: 9581821
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Specificity of rabbit cytochrome P-450 isozymes involved in the metabolic activation of the food derived mutagen 2-amino-3-methylimidazo[4,5-f] quinoline.
    McManus ME; Burgess W; Snyderwine E; Stupans I
    Cancer Res; 1988 Aug; 48(16):4513-9. PubMed ID: 3396004
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Metabolic activation of pyrolysate arylamines by human liver microsomes; possible involvement of a P-488-H type cytochrome P-450.
    Yamazoe Y; Abu-Zeid M; Yamauchi K; Kato R
    Jpn J Cancer Res; 1988 Nov; 79(11):1159-67. PubMed ID: 3147272
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Effect of tryptamine on the mutagenic activity of 2-amino-3-methylimidazo(4,5-f) quinoline (IQ) and related azaarenes in the Ames test.
    Abu-Shakra A; Ioannides C; Walker R
    Mutagenesis; 1987 Jan; 2(1):51-6. PubMed ID: 3331694
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Differential mutagenic activity of IQ (2-amino-3-methylimidazo[4,5-f]quinoline) in Salmonella typhimurium strains in vitro and in vivo, in Drosophila, and in mice.
    Wild D; Gocke E; Harnasch D; Kaiser G; King MT
    Mutat Res; 1985; 156(1-2):93-102. PubMed ID: 3923347
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Biotransformation of the anthraquinones emodin and chrysophanol by cytochrome P450 enzymes. Bioactivation to genotoxic metabolites.
    Mueller SO; Stopper H; Dekant W
    Drug Metab Dispos; 1998 Jun; 26(6):540-6. PubMed ID: 9616189
    [TBL] [Abstract][Full Text] [Related]  

  • 32. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Activation of the food-derived mutagen 2-amino-3-methylimidazo[4, 5-f]quinoline by human-liver microsomes.
    McManus ME; Burgess W; Stupans I; Trainor KJ; Fenech M; Robson RA; Morley AA; Snyderwine EG
    Mutat Res; 1988 Feb; 204(2):185-93. PubMed ID: 3278209
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Metabolic activation of 2-amino-3-methylimidazo(4,5-f)quinoline by hepatic preparations--contribution of the cytosolic fraction and its significance to strain differences.
    Abu-Shakra A; Ioannides C; Walker R
    Mutagenesis; 1986 Sep; 1(5):367-70. PubMed ID: 3331675
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Expression of human cytochrome P450 1A2 in Escherichia coli: a system for biotransformation and genotoxicity studies of chemical carcinogens.
    Kranendonk M; Mesquita P; Laires A; Vermeulen NP; Rueff J
    Mutagenesis; 1998 May; 13(3):263-9. PubMed ID: 9643585
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibitory effect of dietary 4-ipomeanol on DNA adduct formation by the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in male CDF1 mice.
    Cummings DA; Schut HA
    Carcinogenesis; 1995 Oct; 16(10):2523-9. PubMed ID: 7586161
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Metabolic activation of environmental carcinogens and mutagens by human liver microsomes. Role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver.
    Shimada T; Okuda Y
    Biochem Pharmacol; 1988 Feb; 37(3):459-65. PubMed ID: 3337745
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Development of a new genotoxicity test system with Salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase.
    Aryal P; Yoshikawa K; Terashita T; Guengerich FP; Shimada T; Oda Y
    Mutat Res; 1999 Jun; 442(2):113-20. PubMed ID: 10393280
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Evaluation of the antimutagenic potential of anthracene: in vitro and ex vivo studies.
    Bu-Abbas A; Ioannides C; Walker R
    Mutat Res; 1994 Aug; 309(1):101-7. PubMed ID: 7519726
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mechanisms of cytochrome P450 1A2-mediated formation of N-hydroxy arylamines and heterocyclic amines and their reaction with guanyl residues.
    Guengerich FP; Humphreys WG; Yun CH; Hammons GJ; Kadlubar FF; Seto Y; Okazaki O; Martin MV
    Princess Takamatsu Symp; 1995; 23():78-84. PubMed ID: 8844798
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.