132 related articles for article (PubMed ID: 9168259)
1. Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1-aminobenzotriazole.
Kent UM; Bend JR; Chamberlin BA; Gage DA; Hollenberg PF
Chem Res Toxicol; 1997 May; 10(5):600-8. PubMed ID: 9168259
[TBL] [Abstract][Full Text] [Related]
2. Significance of glycine 478 in the metabolism of N-benzyl-1-aminobenzotriazole to reactive intermediates by cytochrome P450 2B1.
Kent UM; Hanna IH; Szklarz GD; Vaz AD; Halpert JR; Bend JR; Hollenberg PF
Biochemistry; 1997 Sep; 36(39):11707-16. PubMed ID: 9305960
[TBL] [Abstract][Full Text] [Related]
3. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
Woodcroft KJ; Webb CD; Yao M; Weedon AC; Bend JR
Chem Res Toxicol; 1997 May; 10(5):589-99. PubMed ID: 9168258
[TBL] [Abstract][Full Text] [Related]
4. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by n-propylxanthate.
Kent UM; Yanev S; Hollenberg PF
Chem Res Toxicol; 1999 Apr; 12(4):317-22. PubMed ID: 10207119
[TBL] [Abstract][Full Text] [Related]
5. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2-phenyl-2-(1-piperidinyl)propane.
Chun J; Kent UM; Moss RM; Sayre LM; Hollenberg PF
Drug Metab Dispos; 2000 Aug; 28(8):905-11. PubMed ID: 10901699
[TBL] [Abstract][Full Text] [Related]
6. Mechanistic studies of cytochrome P450 2B1 inactivation by xanthates.
Yanev SG; Kent UM; Roberts ES; Ballou DP; Hollenberg PF
Arch Biochem Biophys; 2000 Jun; 378(1):157-66. PubMed ID: 10871056
[TBL] [Abstract][Full Text] [Related]
7. Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine.
Kent UM; Pascual L; Roof RA; Ballou DP; Hollenberg PF
Arch Biochem Biophys; 2004 Mar; 423(2):277-87. PubMed ID: 15001392
[TBL] [Abstract][Full Text] [Related]
8. Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1.
Goosen TC; Mills DE; Hollenberg PF
J Pharmacol Exp Ther; 2001 Jan; 296(1):198-206. PubMed ID: 11123381
[TBL] [Abstract][Full Text] [Related]
9. Kinetics and selectivity of mechanism-based inhibition of guinea pig hepatic and pulmonary cytochrome P450 by N-benzyl-1-aminobenzotriazole and N-alpha-methylbenzyl-1-aminobenzotriazole.
Sinal CJ; Bend JR
Drug Metab Dispos; 1996 Sep; 24(9):996-1001. PubMed ID: 8886610
[TBL] [Abstract][Full Text] [Related]
10. Mechanism-based inactivation of cytochrome P450 2B1 by 8-methoxypsoralen and several other furanocoumarins.
Koenigs LL; Trager WF
Biochemistry; 1998 Sep; 37(38):13184-93. PubMed ID: 9748325
[TBL] [Abstract][Full Text] [Related]
11. Inactivation of cytochrome P450 2B1 by benzyl isothiocyanate, a chemopreventative agent from cruciferous vegetables.
Goosen TC; Kent UM; Brand L; Hollenberg PF
Chem Res Toxicol; 2000 Dec; 13(12):1349-59. PubMed ID: 11123978
[TBL] [Abstract][Full Text] [Related]
12. Selectivity and kinetics of inactivation of rabbit hepatic cytochromes P450 2B4 and 2B5 by N-aralkylated derivatives of 1-aminobenzotriazole.
Grimm SW; Bend JR; Halpert JR
Drug Metab Dispos; 1995 May; 23(5):577-83. PubMed ID: 7587934
[TBL] [Abstract][Full Text] [Related]
13. Identification of amino acid residues involved in the inactivation of cytochrome P450 2B1 by two acetylenic compounds: the role of three residues in nonsubstrate recognition Sites.
Von Weymarn LB; Sridar C; Hollenberg PF
J Pharmacol Exp Ther; 2004 Oct; 311(1):71-9. PubMed ID: 15178696
[TBL] [Abstract][Full Text] [Related]
14. Mechanism-based inactivation of cytochrome P450 2B1 by 7-ethynylcoumarin: verification of apo-P450 adduction by electrospray ion trap mass spectrometry.
Regal KA; Schrag ML; Kent UM; Wienkers LC; Hollenberg PF
Chem Res Toxicol; 2000 Apr; 13(4):262-70. PubMed ID: 10775326
[TBL] [Abstract][Full Text] [Related]
15. Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites.
Kent UM; Mills DE; Rajnarayanan RV; Alworth WL; Hollenberg PF
J Pharmacol Exp Ther; 2002 Feb; 300(2):549-58. PubMed ID: 11805216
[TBL] [Abstract][Full Text] [Related]
16. The functional role of threonine-205 in the mechanism-based inactivation of P450 2B1 by two ethynyl substrates: the importance of the F helix in catalysis.
Lin HL; Kent UM; Zhang H; Waskell L; Hollenberg PF
J Pharmacol Exp Ther; 2004 Dec; 311(3):855-63. PubMed ID: 15302894
[TBL] [Abstract][Full Text] [Related]
17. Mechanism-based inactivation of rat liver cytochrome P-450 2B1 by 2-methoxy-5-nitrobenzyl bromide.
Armstrong AP; Hollenberg PF
Drug Metab Dispos; 1999 Jun; 27(6):741-5. PubMed ID: 10348806
[TBL] [Abstract][Full Text] [Related]
18. Mechanism-based inactivation of cytochromes P450 2E1 and 2B1 by 5-phenyl-1-pentyne.
Roberts ES; Alworth WL; Hollenberg PF
Arch Biochem Biophys; 1998 Jun; 354(2):295-302. PubMed ID: 9637739
[TBL] [Abstract][Full Text] [Related]
19. Inactivation of cytochrome P450 2E1 by benzyl isothiocyanate.
Moreno RL; Kent UM; Hodge K; Hollenberg PF
Chem Res Toxicol; 1999 Jul; 12(7):582-7. PubMed ID: 10409397
[TBL] [Abstract][Full Text] [Related]
20. Inactivation of cytochrome P4502B1 by the monoamine oxidase inhibitors R-(-)-deprenyl and clorgyline.
Sharma U; Roberts ES; Hollenberg PF
Drug Metab Dispos; 1996 Jun; 24(6):669-75. PubMed ID: 8781784
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
