BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

83 related articles for article (PubMed ID: 9171876)

  • 1. Anesthetic activity of novel water-soluble 2 beta-morpholinyl steroids and their modulatory effects at GABAA receptors.
    Anderson A; Boyd AC; Byford A; Campbell AC; Gemmell DK; Hamilton NM; Hill DR; Hill-Venning C; Lambert JJ; Maidment MS; May V; Marshall RJ; Peters JA; Rees DC; Stevenson D; Sundaram H
    J Med Chem; 1997 May; 40(11):1668-81. PubMed ID: 9171876
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The anaesthetic action and modulation of GABAA receptor activity by the novel water-soluble aminosteroid Org 20599.
    Hill-Venning C; Peters JA; Callachan H; Lambert JJ; Gemmell DK; Anderson A; Byford A; Hamilton N; Hill DR; Marshall RJ; Campbell AC
    Neuropharmacology; 1996; 35(9-10):1209-22. PubMed ID: 9014136
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulation by general anaesthetics of rat GABAA receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells.
    Davies PA; Kirkness EF; Hales TG
    Br J Pharmacol; 1997 Mar; 120(5):899-909. PubMed ID: 9138697
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Steroid modulation of the GABAA receptor complex: electrophysiological studies.
    Lambert JJ; Peters JA; Sturgess NC; Hales TG
    Ciba Found Symp; 1990; 153():56-71; discussion 71-82. PubMed ID: 1963400
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
    Zeng CM; Manion BD; Benz A; Evers AS; Zorumski CF; Mennerick S; Covey DF
    J Med Chem; 2005 Apr; 48(8):3051-9. PubMed ID: 15828844
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates.
    Turner DM; Ransom RW; Yang JS; Olsen RW
    J Pharmacol Exp Ther; 1989 Mar; 248(3):960-6. PubMed ID: 2539464
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The actions of endogenous and synthetic pregnane steroids on GABAA receptors.
    Hill-Venning C; Lambert JJ; Peters JA; Hales TG; Gill C; Callachan H; Sturgess NC
    Adv Biochem Psychopharmacol; 1992; 47():93-102. PubMed ID: 1324591
    [No Abstract]   [Full Text] [Related]  

  • 8. Correlation of neuroactive steroid modulation of [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding and gamma-aminobutyric acidA receptor function.
    Hawkinson JE; Kimbrough CL; Belelli D; Lambert JJ; Purdy RH; Lan NC
    Mol Pharmacol; 1994 Nov; 46(5):977-85. PubMed ID: 7969089
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 3 alpha-Hydroxy-3 beta-(phenylethynyl)-5 beta-pregnan-20-ones: synthesis and pharmacological activity of neuroactive steroids with high affinity for GABAA receptors.
    Upasani RB; Yang KC; Acosta-Burruel M; Konkoy CS; McLellan JA; Woodward RM; Lan NC; Carter RB; Hawkinson JE
    J Med Chem; 1997 Jan; 40(1):73-84. PubMed ID: 9016330
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neurosteroid analogues. 9. Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
    Jiang X; Manion BD; Benz A; Rath NP; Evers AS; Zorumski CF; Mennerick S; Covey DF
    J Med Chem; 2003 Dec; 46(25):5334-48. PubMed ID: 14640542
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3 alpha-Hydroxy-3 beta-trifluoromethyl-5 alpha-pregnan-20-one (Co 2-1970): a partial agonist at the neuroactive steroid site of the gamma-aminobutyric acidA receptor.
    Hawkinson JE; Drewe JA; Kimbrough CL; Chen JS; Hogenkamp DJ; Lan NC; Gee KW; Shen KZ; Whittemore ER; Woodward RM
    Mol Pharmacol; 1996 May; 49(5):897-906. PubMed ID: 8622640
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conformationally constrained anesthetic steroids that modulate GABA(A) receptors.
    Anderson A; Boyd AC; Clark JK; Fielding L; Gemmell DK; Hamilton NM; Maidment MS; May V; McGuire R; McPhail P; Sansbury FH; Sundaram H; Taylor R
    J Med Chem; 2000 Nov; 43(22):4118-25. PubMed ID: 11063608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regional gamma-aminobutyric acid sensitivity of t-butylbicyclophosphoro[35S]thionate binding depends on gamma-aminobutyric acidA receptor alpha subunit.
    Korpi ER; Lüddens H
    Mol Pharmacol; 1993 Jul; 44(1):87-92. PubMed ID: 8393526
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bicycloorthocarboxylate convulsants. Potent GABAA receptor antagonists.
    Casida JE; Palmer CJ; Cole LM
    Mol Pharmacol; 1985 Sep; 28(3):246-53. PubMed ID: 2993847
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action.
    Gee KW; Bolger MB; Brinton RE; Coirini H; McEwen BS
    J Pharmacol Exp Ther; 1988 Aug; 246(2):803-12. PubMed ID: 2841455
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enantioselectivity of pregnanolone-induced gamma-aminobutyric acid(A) receptor modulation and anesthesia.
    Covey DF; Nathan D; Kalkbrenner M; Nilsson KR; Hu Y; Zorumski CF; Evers AS
    J Pharmacol Exp Ther; 2000 Jun; 293(3):1009-16. PubMed ID: 10869405
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The interaction of anaesthetic steroids with recombinant glycine and GABAA receptors.
    Weir CJ; Ling AT; Belelli D; Wildsmith JA; Peters JA; Lambert JJ
    Br J Anaesth; 2004 May; 92(5):704-11. PubMed ID: 15033889
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regional variation in steroid anesthetic modulation of [35S]TBPS binding to gamma-aminobutyric acidA receptors in rat brain.
    Sapp DW; Witte U; Turner DM; Longoni B; Kokka N; Olsen RW
    J Pharmacol Exp Ther; 1992 Aug; 262(2):801-8. PubMed ID: 1323664
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex.
    Harrison NL; Majewska MD; Harrington JW; Barker JL
    J Pharmacol Exp Ther; 1987 Apr; 241(1):346-53. PubMed ID: 3033209
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors.
    Hawkinson JE; Acosta-Burruel M; Yang KC; Hogenkamp DJ; Chen JS; Lan NC; Drewe JA; Whittemore ER; Woodward RM; Carter RB; Upasani RB
    J Pharmacol Exp Ther; 1998 Oct; 287(1):198-207. PubMed ID: 9765338
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.