179 related articles for article (PubMed ID: 9171883)
21. Oxanosine Monophosphate Is a Covalent Inhibitor of Inosine 5'-Monophosphate Dehydrogenase.
Yu R; Kim Y; Maltseva N; Braunstein P; Joachimiak A; Hedstrom L
Chem Res Toxicol; 2019 Mar; 32(3):456-466. PubMed ID: 30746940
[TBL] [Abstract][Full Text] [Related]
22. IMPDH as a biological probe for RNA antiviral drug discovery: synthesis, enzymology, molecular docking, and antiviral activity of new ribonucleosides with surrogate bases.
Nair V; Ma X; Shu Q; Zhang F; Uchil V; Cherukupalli GR
Nucleosides Nucleotides Nucleic Acids; 2007; 26(6-7):651-4. PubMed ID: 18066873
[TBL] [Abstract][Full Text] [Related]
23. Assay method for monitoring the inhibitory effects of antimetabolites on the activity of inosinate dehydrogenase in intact human CEM lymphocytes.
Balzarini J; De Clercq E
Biochem J; 1992 Nov; 287 ( Pt 3)(Pt 3):785-90. PubMed ID: 1359876
[TBL] [Abstract][Full Text] [Related]
24. Biochemically directed therapy of leukemia with tiazofurin, a selective blocker of inosine 5'-phosphate dehydrogenase activity.
Tricot GJ; Jayaram HN; Lapis E; Natsumeda Y; Nichols CR; Kneebone P; Heerema N; Weber G; Hoffman R
Cancer Res; 1989 Jul; 49(13):3696-701. PubMed ID: 2567208
[TBL] [Abstract][Full Text] [Related]
25. Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogues. Synthesis, structure, and interactions with IMP dehydrogenase.
Gebeyehu G; Marquez VE; Van Cott A; Cooney DA; Kelley JA; Jayaram HN; Ahluwalia GS; Dion RL; Wilson YA; Johns DG
J Med Chem; 1985 Jan; 28(1):99-105. PubMed ID: 2856943
[TBL] [Abstract][Full Text] [Related]
26. Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase.
Yalowitz JA; Jayaram HN
Curr Med Chem; 2002 Apr; 9(7):749-58. PubMed ID: 11966438
[TBL] [Abstract][Full Text] [Related]
27. Eicar (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide). A novel potent inhibitor of inosinate dehydrogenase activity and guanylate biosynthesis.
Balzarini J; Karlsson A; Wang L; Bohman C; Horská K; Votruba I; Fridland A; Van Aerschot A; Herdewijn P; De Clercq E
J Biol Chem; 1993 Nov; 268(33):24591-8. PubMed ID: 7901217
[TBL] [Abstract][Full Text] [Related]
28. Cytotoxicity of a new IMP dehydrogenase inhibitor, benzamide riboside, to human myelogenous leukemia K562 cells.
Jayaram HN; Gharehbaghi K; Jayaram NH; Rieser J; Krohn K; Paull KD
Biochem Biophys Res Commun; 1992 Aug; 186(3):1600-6. PubMed ID: 1354960
[TBL] [Abstract][Full Text] [Related]
29. Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors.
Franchetti P; Cappellacci L; Pasqualini M; Petrelli R; Jayaprakasan V; Jayaram HN; Boyd DB; Jain MD; Grifantini M
Bioorg Med Chem; 2005 Mar; 13(6):2045-53. PubMed ID: 15727858
[TBL] [Abstract][Full Text] [Related]
30. The chemistry of nicotinamide adenine dinucleotide (NAD) analogues containing C-nucleosides related to nicotinamide riboside.
Pankiewicz KW; Watanabe KA; Lesiak-Watanabe K; Goldstein BM; Jayaram HN
Curr Med Chem; 2002 Apr; 9(7):733-41. PubMed ID: 11966436
[TBL] [Abstract][Full Text] [Related]
31. Synthesis of nonhydrolyzable analogues of thiazole-4-carboxamide and benzamide adenine dinucleotide containing fluorine atom at the C2' of adenine nucleoside: induction of K562 differentiation and inosine monophosphate dehydrogenase inhibitory activity.
Lesiak K; Watanabe KA; Majumdar A; Seidman M; Vanderveen K; Goldstein BM; Pankiewicz KW
J Med Chem; 1997 Aug; 40(16):2533-8. PubMed ID: 9258359
[TBL] [Abstract][Full Text] [Related]
32. Effects of the inhibitors of IMP dehydrogenase, tiazofurin and mycophenolic acid, on glycoprotein metabolism.
Sokoloski JA; Sartorelli AC
Mol Pharmacol; 1985 Dec; 28(6):567-73. PubMed ID: 2867464
[TBL] [Abstract][Full Text] [Related]
33. Induction of Tmolt4 leukemia cell death by 3,3-disubstituted-6,6-pentamethylene-1,5-diazabicyclo[3.1.0]hexane-2-4-diones: specificity for type II inosine 5'-monophasphate dehydrogenase.
Barnes BJ; Izydore RA; Eakin AE; Hall IH
J Pharmacol Exp Ther; 2001 Aug; 298(2):790-6. PubMed ID: 11454943
[TBL] [Abstract][Full Text] [Related]
34. IMP dehydrogenase and action of antimetabolites in human cultured blast cells.
Yamada Y; Goto H; Yoshino M; Ogasawara N
Biochim Biophys Acta; 1990 Mar; 1051(3):209-14. PubMed ID: 1968764
[TBL] [Abstract][Full Text] [Related]
35. Ribose-modified mizoribine analogues: synthesis and biological evaluation.
Franchetti P; Pasqualini M; Cappellacci L; Petrelli R; Vita P; Grifantini M
Nucleosides Nucleotides Nucleic Acids; 2005; 24(10-12):2023-7. PubMed ID: 16438062
[TBL] [Abstract][Full Text] [Related]
36. Modulation of nicotinamide adenine dinucleotide and poly(adenosine diphosphoribose) metabolism by the synthetic "C" nucleoside analogs, tiazofurin and selenazofurin. A new strategy for cancer chemotherapy.
Berger NA; Berger SJ; Catino DM; Petzold SJ; Robins RK
J Clin Invest; 1985 Feb; 75(2):702-9. PubMed ID: 3919063
[TBL] [Abstract][Full Text] [Related]
37. Molecular targets of guanine nucleotides in differentiation, proliferation and apoptosis.
Yalowitz JA; Jayaram HN
Anticancer Res; 2000; 20(4):2329-38. PubMed ID: 10953293
[TBL] [Abstract][Full Text] [Related]
38. Discovery of N-(2,3,5-triazoyl)mycophenolic amide and mycophenolic epoxyketone as novel inhibitors of human IMPDH.
Sunohara K; Mitsuhashi S; Shigetomi K; Ubukata M
Bioorg Med Chem Lett; 2013 Sep; 23(18):5140-4. PubMed ID: 23937979
[TBL] [Abstract][Full Text] [Related]
39. Selective inhibition of human Molt-4 leukemia type II inosine 5'-monophosphate dehydrogenase by the 1,5-diazabicyclo[3.1.0]hexane-2,4-diones.
Barnes BJ; Eakin AE; Izydore RA; Hall IH
Biochemistry; 2000 Nov; 39(45):13641-50. PubMed ID: 11076502
[TBL] [Abstract][Full Text] [Related]
40. Effects of the IMP-dehydrogenase inhibitor, Tiazofurin, in bcr-abl positive acute myelogenous leukemia. Part II. In vitro studies.
Wright DG; Boosalis M; Malek K; Waraska K
Leuk Res; 2004 Nov; 28(11):1137-43. PubMed ID: 15380336
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
