BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 9178166)

  • 1. Transgenic animal models of familial amyotrophic lateral sclerosis.
    Gurney ME
    J Neurol; 1997 May; 244 Suppl 2():S15-20. PubMed ID: 9178166
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pathogenic mechanisms in familial amyotrophic lateral sclerosis due to mutation of Cu, Zn superoxide dismutase.
    Gurney ME; Cutting FB; Zhai P; Andrus PK; Hall ED
    Pathol Biol (Paris); 1996 Jan; 44(1):51-6. PubMed ID: 8734301
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The use of transgenic mouse models of amyotrophic lateral sclerosis in preclinical drug studies.
    Gurney ME
    J Neurol Sci; 1997 Oct; 152 Suppl 1():S67-73. PubMed ID: 9419057
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Familial amyotrophic lateral sclerosis and mutations in the Cu/Zn superoxide dismutase gene].
    Nakano R
    Rinsho Shinkeigaku; 1995 Dec; 35(12):1546-8. PubMed ID: 8752459
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis.
    Facchinetti F; Sasaki M; Cutting FB; Zhai P; MacDonald JE; Reif D; Beal MF; Huang PL; Dawson TM; Gurney ME; Dawson VL
    Neuroscience; 1999; 90(4):1483-92. PubMed ID: 10338314
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease.
    Mourelatos Z; Gonatas NK; Stieber A; Gurney ME; Dal Canto MC
    Proc Natl Acad Sci U S A; 1996 May; 93(11):5472-7. PubMed ID: 8643599
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A low expressor line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase (SOD1) gene develops pathological changes that most closely resemble those in human amyotrophic lateral sclerosis.
    Dal Canto MC; Gurney ME
    Acta Neuropathol; 1997 Jun; 93(6):537-50. PubMed ID: 9194892
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetics of amyotrophic lateral sclerosis.
    Siddique T; Deng HX
    Hum Mol Genet; 1996; 5 Spec No():1465-70. PubMed ID: 8875253
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis.
    Ripps ME; Huntley GW; Hof PR; Morrison JH; Gordon JW
    Proc Natl Acad Sci U S A; 1995 Jan; 92(3):689-93. PubMed ID: 7846037
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
    Gurney ME; Pu H; Chiu AY; Dal Canto MC; Polchow CY; Alexander DD; Caliendo J; Hentati A; Kwon YW; Deng HX
    Science; 1994 Jun; 264(5166):1772-5. PubMed ID: 8209258
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS).
    Dal Canto MC; Gurney ME
    Brain Res; 1995 Apr; 676(1):25-40. PubMed ID: 7796176
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential effects of mutant SOD1 on protein structure of skeletal muscle and spinal cord of familial amyotrophic lateral sclerosis: role of chaperone network.
    Wei R; Bhattacharya A; Hamilton RT; Jernigan AL; Chaudhuri AR
    Biochem Biophys Res Commun; 2013 Aug; 438(1):218-23. PubMed ID: 23886956
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis.
    Andreassen OA; Dedeoglu A; Klivenyi P; Beal MF; Bush AI
    Neuroreport; 2000 Aug; 11(11):2491-3. PubMed ID: 10943709
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis.
    Poon HF; Hensley K; Thongboonkerd V; Merchant ML; Lynn BC; Pierce WM; Klein JB; Calabrese V; Butterfield DA
    Free Radic Biol Med; 2005 Aug; 39(4):453-62. PubMed ID: 16043017
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease.
    Tu PH; Gurney ME; Julien JP; Lee VM; Trojanowski JQ
    Lab Invest; 1997 Apr; 76(4):441-56. PubMed ID: 9111507
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis.
    Almer G; Vukosavic S; Romero N; Przedborski S
    J Neurochem; 1999 Jun; 72(6):2415-25. PubMed ID: 10349851
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutant SOD1 mediated pathogenesis of Amyotrophic Lateral Sclerosis.
    Kaur SJ; McKeown SR; Rashid S
    Gene; 2016 Feb; 577(2):109-18. PubMed ID: 26657039
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Superoxide dismutase-1 (SOD-1) gene mutation-dependent mechanisms of neural degeneration in amyotrophic lateral sclerosis].
    Iłzecka J
    Neurol Neurochir Pol; 2001; 35(3):461-9. PubMed ID: 11732268
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Amyotrophic lateral sclerosis: recent insights from transgenic animal models with SOD1 mutations].
    Aoki M
    Rinsho Shinkeigaku; 2004 Nov; 44(11):788-91. PubMed ID: 15651292
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.