BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

83 related articles for article (PubMed ID: 9178891)

  • 1. Determining mutational fingerprints at the human p53 locus with a yeast functional assay: a new tool for molecular epidemiology.
    Inga A; Iannone R; Monti P; Molina F; Bolognesi M; Abbondandolo A; Iggo R; Fronza G
    Oncogene; 1997 Mar; 14(11):1307-13. PubMed ID: 9178891
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutational fingerprint induced by the antineoplastic drug chloroethyl-cyclohexyl-nitrosourea in mammalian cells.
    Inga A; Iannone R; Campomenosi P; Molina F; Menichini P; Abbondandolo A; Fronza G
    Cancer Res; 1995 Oct; 55(20):4658-63. PubMed ID: 7553645
    [TBL] [Abstract][Full Text] [Related]  

  • 3. N-(2-chloroethyl)-N-nitrosourea tethered to lexitropsin induces minor groove lesions at the p53 cDNA that are more cytotoxic than mutagenic.
    Inga A; Chen FX; Monti P; Aprile A; Campomenosi P; Menichini P; Ottaggio L; Viaggi S; Abbondandolo A; Gold B; Fronza G
    Cancer Res; 1999 Feb; 59(3):689-95. PubMed ID: 9973219
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutation spectra analysis suggests that N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea-induced lesions are subject to transcription-coupled repair in Escherichia coli.
    Iannone R; Inga A; Luque-Romero FL; Menichini P; Abbondandolo A; Abril N; Pueyo C; Fronza G
    Mol Carcinog; 1997 May; 19(1):39-45. PubMed ID: 9180927
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potassium diazoacetate-induced p53 mutations in vitro in relation to formation of O6-carboxymethyl- and O6-methyl-2'-deoxyguanosine DNA adducts: relevance for gastrointestinal cancer.
    Gottschalg E; Scott GB; Burns PA; Shuker DE
    Carcinogenesis; 2007 Feb; 28(2):356-62. PubMed ID: 16926174
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer.
    Inga A; Scott G; Monti P; Aprile A; Abbondandolo A; Burns PA; Fronza G
    Carcinogenesis; 1998 May; 19(5):741-6. PubMed ID: 9635858
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel human p53 mutations that are toxic to yeast can enhance transactivation of specific promoters and reactivate tumor p53 mutants.
    Inga A; Resnick MA
    Oncogene; 2001 Jun; 20(26):3409-19. PubMed ID: 11423991
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay.
    Inga A; Monti P; Fronza G; Darden T; Resnick MA
    Oncogene; 2001 Jan; 20(4):501-13. PubMed ID: 11313981
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UV-induced mutagenesis of human p53: analysis using a double-selection method in yeast.
    Moshinsky DJ; Wogan GN
    Environ Mol Mutagen; 2000; 35(1):31-8. PubMed ID: 10692225
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional analysis of chemically-induced mutations at the flounder TP53 locus, the FACIM assay.
    Cachot J; Couteau J; Frébourg T; Leboulenger F; Flaman JM
    Mutat Res; 2004 Aug; 552(1-2):51-60. PubMed ID: 15288541
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Establishment of mouse p53 yeast functional assay and evaluation of its detectability of p53 gene mutation].
    Tsunematsu I
    Hokkaido Igaku Zasshi; 1999 Jul; 74(4):301-14. PubMed ID: 10480037
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analysis of p53 status in human cell lines using a functional assay in yeast: detection of new non-sense p53 mutation in codon 124.
    Smardová J; Pavlová S; Svitáková M; Grochová D; Ravcuková B
    Oncol Rep; 2005 Oct; 14(4):901-7. PubMed ID: 16142349
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Analysis of transcript mutations due to transcriptional slippage in rat p53 tumor suppressor gene with the use of yeast functional assay].
    Ba Y
    Hokkaido Igaku Zasshi; 1999 May; 74(3):173-88. PubMed ID: 10422562
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements.
    Campomenosi P; Monti P; Aprile A; Abbondandolo A; Frebourg T; Gold B; Crook T; Inga A; Resnick MA; Iggo R; Fronza G
    Oncogene; 2001 Jun; 20(27):3573-9. PubMed ID: 11429705
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutational signature of the proximate bladder carcinogen N-hydroxy-4-acetylaminobiphenyl: inconsistency with the p53 mutational spectrum in bladder cancer.
    Besaratinia A; Bates SE; Pfeifer GP
    Cancer Res; 2002 Aug; 62(15):4331-8. PubMed ID: 12154037
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release.
    Röhn TA; Wagenknecht B; Roth W; Naumann U; Gulbins E; Krammer PH; Walczak H; Weller M
    Oncogene; 2001 Jul; 20(31):4128-37. PubMed ID: 11464279
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acetaldehyde-induced mutational pattern in the tumour suppressor gene TP53 analysed by use of a functional assay, the FASAY (functional analysis of separated alleles in yeast).
    Paget V; Lechevrel M; Sichel F
    Mutat Res; 2008 Mar; 652(1):12-9. PubMed ID: 18242117
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tumour p53 mutations exhibit promoter selective dominance over wild type p53.
    Monti P; Campomenosi P; Ciribilli Y; Iannone R; Inga A; Abbondandolo A; Resnick MA; Fronza G
    Oncogene; 2002 Mar; 21(11):1641-8. PubMed ID: 11896595
    [TBL] [Abstract][Full Text] [Related]  

  • 19. UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin.
    Luo JL; Tong WM; Yoon JH; Hergenhahn M; Koomagi R; Yang Q; Galendo D; Pfeifer GP; Wang ZQ; Hollstein M
    Cancer Res; 2001 Nov; 61(22):8158-63. PubMed ID: 11719445
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of 5-methylcytosine in sunlight-induced mutagenesis.
    You YH; Li C; Pfeifer GP
    J Mol Biol; 1999 Oct; 293(3):493-503. PubMed ID: 10543945
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.