BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 9182583)

  • 1. Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH-terminal domain in a similar manner to TIMP-2.
    Bigg HF; Shi YE; Liu YE; Steffensen B; Overall CM
    J Biol Chem; 1997 Jun; 272(24):15496-500. PubMed ID: 9182583
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase.
    Bigg HF; Morrison CJ; Butler GS; Bogoyevitch MA; Wang Z; Soloway PD; Overall CM
    Cancer Res; 2001 May; 61(9):3610-8. PubMed ID: 11325829
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of the tissue inhibitor of metalloproteinases-2 (TIMP-2) binding site on the hemopexin carboxyl domain of human gelatinase A by site-directed mutagenesis. The hierarchical role in binding TIMP-2 of the unique cationic clusters of hemopexin modules III and IV.
    Overall CM; King AE; Sam DK; Ong AD; Lau TT; Wallon UM; DeClerck YA; Atherstone J
    J Biol Chem; 1999 Feb; 274(7):4421-9. PubMed ID: 9933646
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction between tissue inhibitor of metalloproteinases-2 and progelatinase A: immunoreactivity analyses.
    Fujimoto N; Ward RV; Shinya T; Iwata K; Yamashita K; Hayakawa T
    Biochem J; 1996 Feb; 313 ( Pt 3)(Pt 3):827-33. PubMed ID: 8611162
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cell surface-mediated activation of progelatinase A: demonstration of the involvement of the C-terminal domain of progelatinase A in cell surface binding and activation of progelatinase A by primary fibroblasts.
    Ward RV; Atkinson SJ; Reynolds JJ; Murphy G
    Biochem J; 1994 Nov; 304 ( Pt 1)(Pt 1):263-9. PubMed ID: 7998943
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The recombinant catalytic domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) induces activation of progelatinase A and progelatinase A complexed with TIMP-2.
    Lichte A; Kolkenbrock H; Tschesche H
    FEBS Lett; 1996 Nov; 397(2-3):277-82. PubMed ID: 8955363
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reactive site-modified tissue inhibitor of metalloproteinases-2 inhibits the cell-mediated activation of progelatinase A.
    Higashi S; Miyazaki K
    J Biol Chem; 1999 Apr; 274(15):10497-504. PubMed ID: 10187841
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.
    Will H; Atkinson SJ; Butler GS; Smith B; Murphy G
    J Biol Chem; 1996 Jul; 271(29):17119-23. PubMed ID: 8663332
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Domain interactions in the gelatinase A.TIMP-2.MT1-MMP activation complex. The ectodomain of the 44-kDa form of membrane type-1 matrix metalloproteinase does not modulate gelatinase A activation.
    Overall CM; Tam E; McQuibban GA; Morrison C; Wallon UM; Bigg HF; King AE; Roberts CR
    J Biol Chem; 2000 Dec; 275(50):39497-506. PubMed ID: 10991943
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of progelatinase A and progelatinase A/TIMP-2 complex by membrane type 2-matrix metalloproteinase.
    Kolkenbrock H; Hecker-Kia A; Orgel D; Ulbrich N; Will H
    Biol Chem; 1997 Feb; 378(2):71-6. PubMed ID: 9088534
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1.
    Ward RV; Hembry RM; Reynolds JJ; Murphy G
    Biochem J; 1991 Aug; 278 ( Pt 1)(Pt 1):179-87. PubMed ID: 1909113
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutation of the active site glutamic acid of human gelatinase A: effects on latency, catalysis, and the binding of tissue inhibitor of metalloproteinases-1.
    Crabbe T; Zucker S; Cockett MI; Willenbrock F; Tickle S; O'Connell JP; Scothern JM; Murphy G; Docherty AJ
    Biochemistry; 1994 May; 33(21):6684-90. PubMed ID: 7911325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human tissue inhibitor of metalloproteinases 3 interacts with both the N- and C-terminal domains of gelatinases A and B. Regulation by polyanions.
    Butler GS; Apte SS; Willenbrock F; Murphy G
    J Biol Chem; 1999 Apr; 274(16):10846-51. PubMed ID: 10196161
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of the autoactivation of human 72-kDa progelatinase by tissue inhibitor of metalloproteinases-2.
    Howard EW; Bullen EC; Banda MJ
    J Biol Chem; 1991 Jul; 266(20):13064-9. PubMed ID: 2071592
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2).
    Fridman R; Toth M; Peña D; Mobashery S
    Cancer Res; 1995 Jun; 55(12):2548-55. PubMed ID: 7780967
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The hemopexin-like domain (C domain) of human gelatinase A (matrix metalloproteinase-2) requires Ca2+ for fibronectin and heparin binding. Binding properties of recombinant gelatinase A C domain to extracellular matrix and basement membrane components.
    Wallon UM; Overall CM
    J Biol Chem; 1997 Mar; 272(11):7473-81. PubMed ID: 9054449
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human progelatinase A can be activated by autolysis at a rate that is concentration-dependent and enhanced by heparin bound to the C-terminal domain.
    Crabbe T; Ioannou C; Docherty AJ
    Eur J Biochem; 1993 Dec; 218(2):431-8. PubMed ID: 8269931
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sequence motifs of tissue inhibitor of metalloproteinases 2 (TIMP-2) determining progelatinase A (proMMP-2) binding and activation by membrane-type metalloproteinase 1 (MT1-MMP).
    Worley JR; Thompkins PB; Lee MH; Hutton M; Soloway P; Edwards DR; Murphy G; Knäuper V
    Biochem J; 2003 Jun; 372(Pt 3):799-809. PubMed ID: 12630911
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Membrane-type-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases.
    Butler GS; Will H; Atkinson SJ; Murphy G
    Eur J Biochem; 1997 Mar; 244(2):653-7. PubMed ID: 9119036
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The complex between a tissue inhibitor of metalloproteinases (TIMP-2) and 72-kDa progelatinase is a metalloproteinase inhibitor.
    Kolkenbrock H; Orgel D; Hecker-Kia A; Noack W; Ulbrich N
    Eur J Biochem; 1991 Jun; 198(3):775-81. PubMed ID: 1646720
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.