BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

41 related articles for article (PubMed ID: 9189770)

  • 1. Construction and biological characterization of an interleukin-12 fusion protein (Flexi-12): delivery to acute myeloid leukemic blasts using adeno-associated virus.
    Anderson R; Macdonald I; Corbett T; Hacking G; Lowdell MW; Prentice HG
    Hum Gene Ther; 1997 Jun; 8(9):1125-35. PubMed ID: 9189770
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Optimized expression and specific activity of IL-12 by directed molecular evolution.
    Leong SR; Chang JC; Ong R; Dawes G; Stemmer WP; Punnonen J
    Proc Natl Acad Sci U S A; 2003 Feb; 100(3):1163-8. PubMed ID: 12529500
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Riboswitch-controlled IL-12 gene therapy reduces hepatocellular cancer in mice.
    Düchs MJ; Kratzer RF; Vieyra-Garcia P; Strobel B; Schönberger T; Groß P; Aljayyoussi G; Gupta A; Lang I; Klein H; Morilla SM; Hopf S; Park J; Kreuz S; Klugmann M; Igney FH
    Front Immunol; 2024; 15():1360063. PubMed ID: 38558809
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Defining the Basal and Immunomodulatory Mediator-Induced Phosphoprotein Signature in Pediatric B Cell Acute Lymphoblastic Leukemia (B-ALL) Diagnostic Samples.
    Khanolkar A; Liu G; Simpson Schneider BM
    Int J Mol Sci; 2023 Sep; 24(18):. PubMed ID: 37762241
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The chemical biology of IL-12 production
    Koch PD; Pittet MJ; Weissleder R
    RSC Chem Biol; 2020 Oct; 1(4):166-176. PubMed ID: 34458756
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IL-12 reprograms CAR-expressing natural killer T cells to long-lived Th1-polarized cells with potent antitumor activity.
    Landoni E; Woodcock MG; Barragan G; Casirati G; Cinella V; Stucchi S; Flick LM; Withers TA; Hudson H; Casorati G; Dellabona P; Genovese P; Savoldo B; Metelitsa LS; Dotti G
    Nat Commun; 2024 Jan; 15(1):89. PubMed ID: 38167707
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nanoparticle-mediated tumor cell expression of mIL-12 via systemic gene delivery treats syngeneic models of murine lung cancers.
    Ahn HH; Carrington C; Hu Y; Liu HW; Ng C; Nam H; Park A; Stace C; West W; Mao HQ; Pomper MG; Ullman CG; Minn I
    Sci Rep; 2021 May; 11(1):9733. PubMed ID: 33958660
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.
    Glassman CR; Mathiharan YK; Jude KM; Su L; Panova O; Lupardus PJ; Spangler JB; Ely LK; Thomas C; Skiniotis G; Garcia KC
    Cell; 2021 Feb; 184(4):983-999.e24. PubMed ID: 33606986
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.
    Roybal KT; Williams JZ; Morsut L; Rupp LJ; Kolinko I; Choe JH; Walker WJ; McNally KA; Lim WA
    Cell; 2016 Oct; 167(2):419-432.e16. PubMed ID: 27693353
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma.
    Zhang L; Morgan RA; Beane JD; Zheng Z; Dudley ME; Kassim SH; Nahvi AV; Ngo LT; Sherry RM; Phan GQ; Hughes MS; Kammula US; Feldman SA; Toomey MA; Kerkar SP; Restifo NP; Yang JC; Rosenberg SA
    Clin Cancer Res; 2015 May; 21(10):2278-88. PubMed ID: 25695689
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production.
    Jalah R; Rosati M; Ganneru B; Pilkington GR; Valentin A; Kulkarni V; Bergamaschi C; Chowdhury B; Zhang GM; Beach RK; Alicea C; Broderick KE; Sardesai NY; Pavlakis GN; Felber BK
    J Biol Chem; 2013 Mar; 288(9):6763-76. PubMed ID: 23297419
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clinical evaluation of cellular immunotherapy in acute myeloid leukaemia.
    Smits EL; Lee C; Hardwick N; Brooks S; Van Tendeloo VF; Orchard K; Guinn BA
    Cancer Immunol Immunother; 2011 Jun; 60(6):757-69. PubMed ID: 21519825
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts.
    Kerkar SP; Muranski P; Kaiser A; Boni A; Sanchez-Perez L; Yu Z; Palmer DC; Reger RN; Borman ZA; Zhang L; Morgan RA; Gattinoni L; Rosenberg SA; Trinchieri G; Restifo NP
    Cancer Res; 2010 Sep; 70(17):6725-34. PubMed ID: 20647327
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cloning and characterization of an adenoviral vector for highly efficient and doxycycline-suppressible expression of bioactive human single-chain interleukin 12 in colon cancer.
    Wulff H; Krieger T; Krüger K; Stahmer I; Thaiss F; Schäfer H; Block A
    BMC Biotechnol; 2007 Jun; 7():35. PubMed ID: 17594499
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A vector expressing feline mature IL-18 fused to IL-1beta antagonist protein signal sequence is an effective adjuvant to a DNA vaccine for feline leukaemia virus.
    O'Donovan LH; McMonagle EL; Taylor S; Bain D; Pacitti AM; Golder MC; McDonald M; Hanlon L; Onions DE; Argyle DJ; Jarrett O; Nicolson L
    Vaccine; 2005 May; 23(29):3814-23. PubMed ID: 15893619
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An inducible caspase 9 safety switch for T-cell therapy.
    Straathof KC; Pulè MA; Yotnda P; Dotti G; Vanin EF; Brenner MK; Heslop HE; Spencer DM; Rooney CM
    Blood; 2005 Jun; 105(11):4247-54. PubMed ID: 15728125
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of recombinant adenovirus-mediated expression of IL-2 and IL-12 in human B lymphoma cells on co-cultured PBMC.
    Ebert O; Wilbert D; Buttgereit P; Ziske C; Flieger D; Schmidt-Wolf IG
    Genet Vaccines Ther; 2004 Oct; 2(1):15. PubMed ID: 15485577
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro co-stimulation with anti-CD28 synergizes with IL-12 in the generation of T cell immune responses to leukaemic cells; a strategy for ex-vivo generation of CTL for immunotherapy.
    Orleans-Lindsay JK; Deru A; Craig JI; Prentice HG; Lowdell MW
    Clin Exp Immunol; 2003 Sep; 133(3):467-75. PubMed ID: 12930376
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Improved antitumour immunity in murine neuroblastoma using a combination of IL-2 and IL-12.
    Siapati KE; Barker S; Kinnon C; Michalski A; Anderson R; Brickell P; Thrasher AJ; Hart SL
    Br J Cancer; 2003 May; 88(10):1641-8. PubMed ID: 12771934
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 3.