These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 9190287)

  • 1. FR900482, a close cousin of mitomycin C that exploits mitosene-based DNA cross-linking.
    Williams RM; Rajski SR; Rollins SB
    Chem Biol; 1997 Feb; 4(2):127-37. PubMed ID: 9190287
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FR900482 class of anti-tumor drugs cross-links oncoprotein HMG I/Y to DNA in vivo.
    Beckerbauer L; Tepe JJ; Cullison J; Reeves R; Williams RM
    Chem Biol; 2000 Oct; 7(10):805-12. PubMed ID: 11033083
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interstrand cross-linking of DNA by FK317 and its deacetylated metabolites FR70496 and FR157471.
    Williams RM; Ducept P
    Biochemistry; 2003 Dec; 42(49):14696-701. PubMed ID: 14661983
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The mitomycin bioreductive antitumor agents: cross-linking and alkylation of DNA as the molecular basis of their activity.
    Tomasz M; Palom Y
    Pharmacol Ther; 1997; 76(1-3):73-87. PubMed ID: 9535170
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Monoalkylation of DNA by reductively activated FR66979.
    Paz MM; Sigurdsson ST; Hopkins PB
    Bioorg Med Chem; 2000 Jan; 8(1):173-9. PubMed ID: 10968276
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reductive alkylation of DNA by mitomycin A, a mitomycin with high redox potential.
    McGuinness BF; Lipman R; Goldstein J; Nakanishi K; Tomasz M
    Biochemistry; 1991 Jul; 30(26):6444-53. PubMed ID: 1905153
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C.
    Suresh Kumar G; Lipman R; Cummings J; Tomasz M
    Biochemistry; 1997 Nov; 36(46):14128-36. PubMed ID: 9369485
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity.
    Paz MM; Das TA; Tomasz M
    Bioorg Med Chem; 1999 Dec; 7(12):2713-26. PubMed ID: 10658576
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Studies related to antitumor antibiotics. Part V. Reactions of mitomycin C with DNA examined by ethidium fluorescence assay.
    Lown JW; Begleiter A; Johnson D; Morgan AR
    Can J Biochem; 1976 Feb; 54(2):110-9. PubMed ID: 4201
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective activation of mitomycin A by thiols to form DNA cross-links and monoadducts: biochemical basis for the modulation of mitomycin cytotoxicity by the quinone redox potential.
    Paz MM; Das A; Palom Y; He QY; Tomasz M
    J Med Chem; 2001 Aug; 44(17):2834-42. PubMed ID: 11495594
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation.
    Maliepaard M; de Mol NJ; Tomasz M; Gargiulo D; Janssen LH; van Duynhoven JP; van Velzen EJ; Verboom W; Reinhoudt DN
    Biochemistry; 1997 Jul; 36(30):9211-20. PubMed ID: 9230054
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Relative toxicities of DNA cross-links and monoadducts: new insights from studies of decarbamoyl mitomycin C and mitomycin C.
    Palom Y; Suresh Kumar G; Tang LQ; Paz MM; Musser SM; Rockwell S; Tomasz M
    Chem Res Toxicol; 2002 Nov; 15(11):1398-406. PubMed ID: 12437330
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Isolation and structure of an intrastrand cross-link adduct of mitomycin C and DNA.
    Bizanek R; McGuinness BF; Nakanishi K; Tomasz M
    Biochemistry; 1992 Mar; 31(12):3084-91. PubMed ID: 1554696
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of glutathione on alkylation and cross-linking of DNA by mitomycin C. Isolation of a ternary glutathione-mitomycin-DNA adduct.
    Sharma M; He QY; Tomasz M
    Chem Res Toxicol; 1994; 7(3):401-7. PubMed ID: 8075372
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reductive activation of potential antitumor mitosene compounds.
    Maliepaard M; de Mol NJ; Janssen LH; Hoogvliet JC; van der Neut W; Verboom W; Reinhoudt DN
    J Med Chem; 1993 Jul; 36(15):2091-7. PubMed ID: 8340912
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insight Into Factors Governing Formation, Synthesis and Stereochemical Configuration of DNA Adducts Formed by Mitomycins.
    Paz MM; Champeil E
    Chem Rec; 2023 Jan; 23(1):e202200193. PubMed ID: 36251922
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Orientation isomers of the mitomycin C interstrand cross-link in non-self-complementary DNA. Differential effect of the two isomers on restriction endonuclease cleavage at a nearby site.
    Kumar S; Johnson WS; Tomasz M
    Biochemistry; 1993 Feb; 32(5):1364-72. PubMed ID: 8448145
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and function modification of DNA by mitomycin C. Mechanism of the DNA sequence specificity of mitomycins.
    Gargiulo D; Kumar GS; Musser SS; Tomasz M
    Nucleic Acids Symp Ser; 1995; (34):169-70. PubMed ID: 8841606
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chemical modification of DNA with muta-carcinogens. III. Reductive alkylation of DNA with mitomycin C.
    Hashimoto Y; Shudo K
    Environ Health Perspect; 1985 Oct; 62():219-22. PubMed ID: 3936706
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and DNA cross-linking of a phototriggered FR900482 mitosene progenitor.
    Judd TC; Williams RM
    Org Lett; 2002 Oct; 4(21):3711-4. PubMed ID: 12375925
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.