BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 9192639)

  • 1. Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines.
    Nielsen M; Kaltoft K; Nordahl M; Röpke C; Geisler C; Mustelin T; Dobson P; Svejgaard A; Odum N
    Proc Natl Acad Sci U S A; 1997 Jun; 94(13):6764-9. PubMed ID: 9192639
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells.
    Nielsen M; Kaestel CG; Eriksen KW; Woetmann A; Stokkedal T; Kaltoft K; Geisler C; Röpke C; Odum N
    Leukemia; 1999 May; 13(5):735-8. PubMed ID: 10374878
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Constitutive activation of STAT transcription factors in acute myelogenous leukemia.
    Spiekermann K; Biethahn S; Wilde S; Hiddemann W; Alves F
    Eur J Haematol; 2001 Aug; 67(2):63-71. PubMed ID: 11722592
    [TBL] [Abstract][Full Text] [Related]  

  • 4. JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.
    Wang LH; Kirken RA; Erwin RA; Yu CR; Farrar WL
    J Immunol; 1999 Apr; 162(7):3897-904. PubMed ID: 10201908
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells.
    Eriksen KW; Kaltoft K; Mikkelsen G; Nielsen M; Zhang Q; Geisler C; Nissen MH; Röpke C; Wasik MA; Odum N
    Leukemia; 2001 May; 15(5):787-93. PubMed ID: 11368440
    [TBL] [Abstract][Full Text] [Related]  

  • 6. STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma.
    Brender C; Nielsen M; Kaltoft K; Mikkelsen G; Zhang Q; Wasik M; Billestrup N; Odum N
    Blood; 2001 Feb; 97(4):1056-62. PubMed ID: 11159537
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells.
    Garcia R; Bowman TL; Niu G; Yu H; Minton S; Muro-Cacho CA; Cox CE; Falcone R; Fairclough R; Parsons S; Laudano A; Gazit A; Levitzki A; Kraker A; Jove R
    Oncogene; 2001 May; 20(20):2499-513. PubMed ID: 11420660
    [TBL] [Abstract][Full Text] [Related]  

  • 8. JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells.
    De Vos J; Jourdan M; Tarte K; Jasmin C; Klein B
    Br J Haematol; 2000 Jun; 109(4):823-8. PubMed ID: 10929036
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of signal transducer and activator of transcription 3 (STAT3) in gastrointestinal stromal tumors.
    Paner GP; Silberman S; Hartman G; Micetich KC; Aranha GV; Alkan S
    Anticancer Res; 2003; 23(3B):2253-60. PubMed ID: 12894500
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neuregulin-1 activates the JAK-STAT pathway and regulates lung epithelial cell proliferation.
    Liu J; Kern JA
    Am J Respir Cell Mol Biol; 2002 Sep; 27(3):306-13. PubMed ID: 12204892
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Blockade of constitutively activated Janus kinase/signal transducer and activator of transcription-3 pathway inhibits growth of human pancreatic cancer.
    Toyonaga T; Nakano K; Nagano M; Zhao G; Yamaguchi K; Kuroki S; Eguchi T; Chijiiwa K; Tsuneyoshi M; Tanaka M
    Cancer Lett; 2003 Nov; 201(1):107-16. PubMed ID: 14580692
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells.
    Burke WM; Jin X; Lin HJ; Huang M; Liu R; Reynolds RK; Lin J
    Oncogene; 2001 Nov; 20(55):7925-34. PubMed ID: 11753675
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system.
    Sriuranpong V; Park JI; Amornphimoltham P; Patel V; Nelkin BD; Gutkind JS
    Cancer Res; 2003 Jun; 63(11):2948-56. PubMed ID: 12782602
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells.
    Lundin Brockdorff J; Woetmann A; Mustelin T; Kaltoft K; Zhang Q; Wasik MA; Röpke C; Ødum N
    Cytokine; 2002 Nov; 20(4):141-7. PubMed ID: 12543077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of constitutive STAT3 activity sensitizes resistant non-Hodgkin's lymphoma and multiple myeloma to chemotherapeutic drug-mediated apoptosis.
    Alas S; Bonavida B
    Clin Cancer Res; 2003 Jan; 9(1):316-26. PubMed ID: 12538484
    [TBL] [Abstract][Full Text] [Related]  

  • 16. STAT3, but not ERKs, mediates the IL-6-induced proliferation of renal cancer cells, ACHN and 769P.
    Horiguchi A; Oya M; Marumo K; Murai M
    Kidney Int; 2002 Mar; 61(3):926-38. PubMed ID: 11849447
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation.
    Iwamoto T; Senga T; Naito Y; Matsuda S; Miyake Y; Yoshimura A; Hamaguchi M
    Oncogene; 2000 Sep; 19(41):4795-801. PubMed ID: 11032030
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tyrphostin B42 inhibits IL-12-induced tyrosine phosphorylation and activation of Janus kinase-2 and prevents experimental allergic encephalomyelitis.
    Bright JJ; Du C; Sriram S
    J Immunol; 1999 May; 162(10):6255-62. PubMed ID: 10229872
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.
    Blaskovich MA; Sun J; Cantor A; Turkson J; Jove R; Sebti SM
    Cancer Res; 2003 Mar; 63(6):1270-9. PubMed ID: 12649187
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IL-15 and IL-17F are differentially regulated and expressed in mycosis fungoides (MF).
    Willerslev-Olsen A; Litvinov IV; Fredholm SM; Petersen DL; Sibbesen NA; Gniadecki R; Zhang Q; Bonefeld CM; Wasik MA; Geisler C; Zhou Y; Woetmann A; Sasseville D; Krejsgaard T; Odum N
    Cell Cycle; 2014; 13(8):1306-12. PubMed ID: 24621498
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.